scholarly journals How different domains of quality of life are associated with latent dimensions of mental health measured by GHQ-12

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Fatemeh Nouri ◽  
Awat Feizi ◽  
Hamidreza Roohafza ◽  
Masoumeh Sadeghi ◽  
Nizal Sarrafzadegan

Abstract Background and objectives A short form of the General Health Questionnaire (GHQ-12) is a useful screening instrument for assessing mental health. Furthermore, Quality of life (QoL) is a critical treatment outcome in many clinical and health care research settings. This study aimed to reassess the dimensionality of GHQ-12 using Multidimensional Graded Response Model (MGRM) and evaluate how its extracted dimensions are associated with the QoL's domains. Methods Isfahan Cohort Study 2 (ICS2) is a population-based, ongoing prospective cohort study among adults aged 35 years and older who were free of cardiovascular diseases (CVDs) at the beginning of the study in 2013. A total of 1316 participants, all living in urban and rural areas of Isfahan and Najafabad, Iran was completed the GHQ-12 and WHO QoL-brief version at baseline. Five competing MGRMs with different latent structures were specified for GHQ-12. Factor scores derived from the best fitted model were used to associate with various domains of QoL. Results: The Three-Dimensional model for GHQ-12 was the best-fitted model explaining the Social Function (SF), Self Confidence (SC), and Anxiety/Depression (A/D) as three correlated yet different latent dimensions of mental health. Our findings in full adjusted multivariate regression models showed that a one-SD increase in dimensions of SC and SF was associated with a 38- to 48%-SD and 27- to 38%-SD increase in the domains scores of QoL, respectively. Moreover, for each one‐SD increase in score of A/D dimension, the domains scores of QoL decreased by 29- to 40%-SD. The highest to the lowest standardized coefficients for all latent dimensions of mental health were respectively related to the psychological, physical health, social relationships, and environmental condition domains of QoL. Furthermore, SC, A/D, and SF dimensions of GHQ-12 showed the highest to the lowest degree of association with all domains of QoL. Conclusions Our findings confirm that the GHQ-12 as a multidimensional rather than unitary instrument measures distinct dimensions of mental health. Furthermore, all aspects of QoL changed when the intensity of latent dimensions of mental health increased. Moreover, the psychological domain of QoL is the most affected by all latent dimensions of mental health, followed by physical health, social relationships, and environmental condition domains. It seems that in an attempt to full recovery as assessed by improved QoL outcomes, treatment of clinical symptoms may not be sufficient. Identifying and differentiating the structures of mental health in each community as well as implementing intervention programs aimed at focusing on specific dimensions may help in the prevention of further deterioration of mental health and improved QoL in the community.

2022 ◽  
Vol 21 (1) ◽  
pp. 90-95
Author(s):  
Md Abdul Qader ◽  
AKM Abu Mottaleb ◽  
Naznin Akter Shetu ◽  
Raonokosh Salehin Khan ◽  
Tanjima Ahad Nisha ◽  
...  

Objectives: Assessment of health related quality of life (HRQOL) is an essential part of evaluation of end stage renal disease (ESRD) as we have conducted this study on haemodialysis patients to see the HRQOL and to asses and compare the parameters which influence physical and mental health. Materials and Methods: This was a single centre study on haemodialysis patients using Short Form 36 (SF-36) of Kidney Disease Quality of Life (KDQOL). All the eight domains of HRQOL were assessed individually as well as summary scores for mental health (MCS Mental composite summary) and physical health (PCS Physical composite summary) were also evaluated. The questionnaire was completed by patient themselves and the clinical data was extracted from the medical records with prior consent from the patient. Results and discussion: The study participants showed a female predominance of 66% with a lower PCS and MCS scores among female participants in comparison to their male counterparts. Overall summary scores showed a lower PCS (38.71±8.15) than MCS (42.79±11.6) which reflects better mental health than physical health in the study population. A multiple regression analysis showed, the presence of residual renal function (β= -0.421, p= 0.02), duration of dialysis (β= 0.405, p= 0.03) and haemoglobin less than 12g/dL (β= 0.379, p= 0.02) were significant predictors of MCS. Conclusion: HRQOL in haemodialysis patients are influenced by socio-demographic as well as clinical parameters. In our population, kidney disease affects physical health more than mental health and the reasons are multifactorial. Bangladesh Journal of Medical Science Vol. 21(1) 2022 Page : 90-95


2020 ◽  
Vol 16 (2) ◽  
pp. 132-137
Author(s):  
Mohammad Vafaee-Shahi ◽  
Mehrnoosh Purfallah ◽  
Elham Shirazi ◽  
Samileh Noorbakhsh

Background & Aim: Attention deficit hyperactivity disorder (ADHD) is the most common mental health disorder among young children that affects the mothers’ lifestyles The aim of the present study was to consider the quality of life in Iranian mothers with ADHD children. Objective: In this comparative study, we compared the quality of life between mothers of ADHD children and mothers of normal children. Methods: In this descriptive study (2018-2019), a total of 75 mothers with ADHD children and 75 mothers with normal children, who were referred to referral educational hospital (Rasoul Hospital; Tehran, Iran) were evaluated. ADHD criteria were assessed by means of the SNAP-IV questionnaire, while the quality of life was evaluated by the SF-36 questionnaire. All data were analyzed by SPSS software. The environmental, mental, social physical, health and quality of life were compared between 2 groups. Results: The economic situation of mothers with normal children was average (73.3%) to good (16%), while in mothers with ADHD children the economic situation was average (45.3%) to poor (37.3%). Mothers’ employment in normal children group was 41.3%, but it was 14.6% in mothers with ADHD children. A significant difference was reported between two groups in the mean of environmental health score (p <0.05), social relationships (p <0.05), mental health (p <0.05), physical health (p <0.01) and quality of life (p <0.01). The mean score of environmental health, social relationships, mental health, physical health and quality of life in ADHD mothers was significantly lower than mothers with normal children. Conclusion: The difficulties in the management of ADHD children negatively affect the quality of mothers’ lifestyles. Therefore, preventive, educational and therapeutic interventions are recommended to improve the mental health and the quality of life of mothers.


2020 ◽  
Vol 7 (3) ◽  
pp. 991-997
Author(s):  
Maria Kilikova

Introduction: The quality of a women's life is very closely related to their health. Oncogynecological disease brings substantial changes into their life that women need to adapt to them. As determination of quality of life is in nurse competence, the quality of life in women with diagnosed oncogynecological illness and surgical treatment has been described in the paper. Aim: The aim of the paper was to examine cancer's influence on the quality of life based on physical health, survival, social relationships, and the environmental domains. Methods: The sample consisted of 84 female respondents with surgical treatment of oncogynecological disease and the patients fulfilled the standardized WHOQOL-BREF questionnaire. Results: The results have shown that patients experienced significant reductions in the quality of life in regard to physical and mental health. Social and environmental domain were significantly less affected. Conclusions: The oncogynecoogical diseases significantly affect quality of life in all four investigated domains, but to a different extent. These findings emphasize an individual approach that takes into account not only the nursing aspect but also the ability to respond to a variety of other related factors that affect the quality of women with oncogynecological disease.


Author(s):  
Zouhour Samlani ◽  
Yassine Lemfadli ◽  
Adil Ait Errami ◽  
Sofia Oubaha ◽  
Khadija Krati

Introduction:The majority of epidemiological reports focus on confirmed cases of COVID-19. In this study, we aim to assess the health and well-being of adults not infected with Covid-19 after two months of quarantine in Morocco.Materials and methods:Two months after the declaration of quarantine in Morocco following the Covid-19 epidemic, we carried out a descriptive cross-sectional study of 279 Moroccan citizens. We used the Short Form Health Survey (SF-12) as a determinant of quality of life, which is based on eight dimensions of health. The data were collected using an electronic questionnaire distributed online. The participants also indicated their socio-demographic data, their knowledge and practices regarding the Covid-19 pandemic and whether they had chronic health problems.Results:The quality of life of all participants was moderately disrupted during the Covid-19 pandemic with a mental health score (MCS) of 34.49 (&plusmn; 6.44) and a physical health score (PCS) of 36.10 (&plusmn; 5.82). Participants with chronic diseases scored lower with 29.28 (&plusmn; 1.23) in mental health (MCS) and 32.51 (&plusmn; 7.14) in physical health (PCS). The seriousness of COVID-19 has an impact on the quality of life and health well-being of people and this impact is more marked in patients with chronic health problems.Conclusion: Our results confirm the need to pay attention to the health of people who have not been infected with the virus. Our results also point out that uninfected people with chronic illnesses may be more likely to have well-being problems due to quarantine restrictions.


2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S415-S415 ◽  
Author(s):  
Evan Tzanis ◽  
Surya Chitra ◽  
Marla Curran ◽  
Paul McGovern ◽  
Jordan Hinahara ◽  
...  

Abstract Background The appearance of multidrug-resistant Gram-positive bacteria is a major challenge in clinical care. Omadacycline is the first aminomethylcycline antibiotic (semisynthetic compounds related to tetracyclines) in late-stage clinical development for acute bacterial skin and skin structure infections (ABSSSI), and demonstrates potent in vitro activity against many pathogens. Methods Seven hundred thirty-five patients were enrolled in the OASIS-2 randomized controlled trial comparing omadacycline and linezolid for the treatment of adult subjects with ABSSSI known or suspected to be due to a Gram-positive pathogen, with 368 and 367 enrolled in each group, respectively. Subjects completed the 36-Item Short Form Health Survey Version 2 (SF-36v2), a validated questionnaire on physical and mental health, at both screening and post-treatment evaluation. Results of the SF-36v2 were analyzed in accordance with established norm-based standards for the survey (Ware 2000) for the intention-to-treat population. Results Subjects who received omadacycline experienced a 3.25 point mean improvement in overall physical health (P &lt; 0.001, Figure 1) and reported significant improvements across all but one component parameter of overall physical and mental health, including physical functioning, bodily pain, role physical, vitality, role emotional, mental health, and social functioning (Figure 2). In contrast, while overall physical health improved for subjects who received linezolid, the improvement in vitality, role emotional, mental health, and general health was not significant (Figure 2). Although omadacycline achieved greater increase from baseline than linezolid across all domains analyzed, the difference in scores was not statistically significant at the P &lt; 0.05 level (Figure 1). Conclusion Omadacycline provides significant improvement in the physical component of quality of life over baseline for adult subjects with ABSSSI known or suspected to be due to a Gram-positive pathogen. Although the OASIS-2 trial was neither designed nor powered to measure differences in quality of life following treatment, trends identified in this analysis merit further investigation. References 1. Ware JE. SF-36 Health Survey Update. SPINE 2000; 25(24); 3130–3139. Disclosures E. Tzanis, Paratek Pharmaceuticals: Employee, Salary. M. Curran, Paratek Pharmaceuticals: Employee, Salary. P. McGovern, Paratek Pharmaceuticals: Employee, Salary. J. Hinahara, Paratek Pharmaceuticals: Consultant, Consulting fee. T. Goss, Paratek Pharmaceuticals: Consultant, Consulting fee.


2015 ◽  
Vol 4 (3) ◽  
pp. 13-16 ◽  
Author(s):  
R K Mehta ◽  
S Subedi ◽  
S Bohora

Globally, diabetes is ranked as the 4th leading cause of death in terms of disease and places a huge strain on public health funding. Quality of life (QOL) is an important and understudied topic in the diabetes. Most studies reports that quality of life among people with diabetes is worse than QOL in general population. Thus, this study is aimed to assess health related quality of life of diabetic patients. We conducted a hospital- based non experimental prospective study. Total 50 diabetic patients were enrolled in this study by using purposive sampling technique. Short-Form 36 questionnaire was used to assess the QOL of diabetic patients. Among 50 respondents, 27 were female and 23 were male. In physical health, 56% respondents had obtained score above 50, 2% respondents had obtained score 50 and 42% respondents had obtained score below 50.Similarly, in mental health, 56% respondents had obtained score above 50 and 44% respondents had obtained score below50. This result indicates that majority of respondents (56%) had better QOL. It concludes that majority (56%) of respondents had better QOL in both physical and mental health and in physical health 2% had average QOL and 42% had poor QOL and in mental health 44% had poor QOL. So, the family, physician, nurses and policy makers can use this finding to identify and implement appropriate interventions for better management and ultimately improving QOL of diabetic patients.DOI: http://dx.doi.org/10.3126/jcmc.v4i3.11933Journal of Chitwan Medical College 2014; 4(3): 13-16 


2021 ◽  
Vol 9 (E) ◽  
pp. 645-652
Author(s):  
Agustina Arundina Triharja Tejoyuwono ◽  
Rangga Putra Nugraha ◽  
Faisal Kholid Fahdi

BACKGROUND: The spread of Coronavirus Disease 2019 (COVID-19) disease which has not been balanced with effective protocols can create mental health problems which could affect the quality of life; as of today, there is not any research that examines the influence of both factors. AIM: This study purpose was to analyze the mental health status on the quality of life amongst medicine students during COVID-19 period. METHODS: This is a cross-sectional survey on 361 students from Faculty of Medicine Tanjungpura University. This study was conducted from June 2019 to November 2020 by spreading Depression Anxiety Stress Scale questionnaire and a WHOQOL-BREF questionnaire through online. The data analysis was administered using Kruskal–Wallis statistics. RESULT: The students’ mental health status was dominantly on the normal category with depression domain by 323 students (89.5%), anxiety domain by 311 students (86.1%), and stress domain by 343 students (95%). The quality of life measurement was in category medium in all domains which are physical health (88.6%), psychological health (92.5%), social relationships (50.7%), and environment (78.7%). There was significant effect of mental health status of depression and anxiety toward the aspect of physical health, psychological health, and social relationships (p < 0.05). Stress significantly influenced all domains of quality of life, and there was no significant effect of mental health status domain depression (p = 0.051) and anxiety (p = 0.881) toward the environment aspect. CONCLUSION: Students’ mental health status in this research belongs to the category normal with moderate level in quality of life. To compare, there was a significant effect of mental health status toward the quality of life domains. The good application of self-coping mechanisms and the social encouragement from the environment is suitable intervention strategies during the pandemic COVID-19 period.


2020 ◽  
Vol 77 (2) ◽  
pp. 158-164
Author(s):  
Branka Gvozdic ◽  
Dragica Milenkovic-Petronic ◽  
Nebojsa Ladjevic ◽  
Aleksandar Vuksanovic ◽  
Otas Durutovic

Background/Aim. Urolithiasis is one of the most common urological illnesses with a continual rise in incidence and prevalence in the population. Its pathogenesis is multifactorial; hence, its consequences are serious problems that can significantly impact the quality of life of patients. In the last years, operational modes of urolithiasis treatment had undergone evolution changes towards minimally invasive treatment techniques aimed at improving its efficacy and patients' life quality. The aim of the study was to examine and evaluate the quality of life of the patients with urolithiasis depending on the applied treatment method. Methods. This research was designed as a panel study ? a combination of a cross-sectional and cohort study. The sample included patients with urolithiasis treated with extracorporeal shock wave lithotripsy (ESWL) or ureteroscopic lithotripsy (Lithoclast). The research was carried during one year period and 100 respondents met the inclusion criteria. They were divided into two equal groups considering the applied method of the stone disintegration: the Lithoclast group (URSL) and the ESWL group. The instrument used for measuring the quality of life was Short Form (SF) 36 questionnaire. It was administrated to the patients immediately before the operation and one month after the operation. Results. The statistical analysis of the scores obtained preoperationally on the SF 36 questionnaire revealed the decrease in the quality of life of patients with urolithiasis in almost all dimensions of life. The statistically relevant difference in preoperative SF scores between the two groups of patients was not established except in the domain of the role of physical health and the domain of mental health. In the domain of the role of physical health, the Lithoclast group had a statistically significant higher score than the ESWL group, but in the domain of mental health, the ESWL group had a statistically significant higher score than the Lithoclast group. The postoperative statistical analysis of SF questionnaire and the examination of the impact of the treatment mode on the quality of life showed that the use of the Lithoclast method resulted in the much higher, statistically significant score at SF36 questionnaires regarding several life dimensions than the ESWL method. The application of the ESWL method even resulted in the decrease in the postoperational score for some life dimensions. Conclusion. The assessment of the quality of life is an adequate tool for the evaluation of treatment modes in the clinical practice. By using the SF 36 questionnaire in this study, we established that the ureteroscopic lithotripsy (the Lithoclast method) is a method that postoperatively results in much higher and statistically significant improvement of the quality of life of patients with urolithiasis in several health domains than the ESWL method.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zeng-Rong Luo ◽  
Dong-Shan Liao ◽  
Liang-Wan Chen

Abstract Background To compare postoperative sexual dysfunction (SD) and quality of life (QOL) in Type A Aortic Dissection (AAD) Patients of Different Ages. Methods From January 2018 to December 2019, 204 AAD postoperative survivors in Union Hospital of Fujian Medical University were selected and were divided into young group (less than 50 years old) and elderly group (more than 50 years old). We evaluated SD according to the male International Erectile Dysfunction Index (IIEF-5) and female sexual function index (FSFI). The Short Form 12 Health Survey Questionnaire (SF-12) and Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) were used to investigate the QOL, Quick Inventory Depressive Symptomatology-Self Report (QIDS-SR) and the Beck Depression Inventory-II (BDI-II) to investigate depressive symptoms. Results One hundred seventy-five patients completed all the questionnaire (85.8%). The total SD prevalence rate was 38.9% (68 cases), with 27.4% of the young (20 cases) and 47.1% of the elderly (48 cases). The age of non-SD and SD patients was 49.0 ± 11.5 and 56.9 ± 10.8 years, respectively (P = 0.03). Compared with non-SD patients, the total physical health of SD patients was significantly worse (P = 0.04), however, the mental health was not significantly worse (P = 0.77); the depressive symptoms did not expressed a significant difference between the SD and non-SD groups (QIDS-SR P = 0.15, BDI-II P = 0.06). Total physical health scores in the young SD group did not show significant better than elderly SD group (P = 0.24), however, total mental health scores showed significantly worse (P = 0.04), depressive symptoms scores were significantly higher (QIDS-SR P = 0.03, BDI-II P = 0.04). Conclusion The postoperative AAD SD prevalence of elderly is higher than that of young, and the total physical health of SD patients is poorer than those without SD patients. The young SD patients did not show a significant higher physical health scores than the elderly SD patients, instead, the young SD patients were more psychologically affected than the elderly SD patients, whose mental health was worse, and depression symptoms were more obvious, suggesting that the factors affecting the QOL of postoperative SD patients are related to physical factors, but the young postoperative SD patients mainly affected by psychological factors.


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