MIA PaCa-2 pancreas cancer cell line – Phenotypic and genotypic characterization

Pancreatology ◽  
2012 ◽  
Vol 12 (6) ◽  
pp. 547
Author(s):  
R. Gradiz ◽  
L. Carvalho ◽  
H. Silva ◽  
R.J. Nobre ◽  
M.F. Botelho ◽  
...  
Pancreatology ◽  
2012 ◽  
Vol 12 (6) ◽  
pp. 548
Author(s):  
R. Gradiz ◽  
A.M. Abrantes ◽  
A.C. Mamede ◽  
M.F. Botelho ◽  
A. Mota-Pinto

2004 ◽  
Vol 59 (7-8) ◽  
pp. 523-527 ◽  
Author(s):  
Steinthor Sigurdsson ◽  
Helga M. Ögmundsdottir ◽  
Sigmundur Gudbjarnason

AbstractThe aim of this work was to study the antiproliferative effect of a tincture from fruits of Angelica archangelica and the active components using the human pancreas cancer cell line PANC-1 as a model. Significant dose-dependent antiproliferative activity was observed in the tincture with an EC50 value of 28.6 μg/ml. Strong antiproliferative activity resulted from the two most abundant furanocoumarins in the tincture, imperatorin and xanthotoxin. The contribution of terpenes to this activity was insignificant. Imperatorin and xanthotoxin proved to be highly antiproliferative, with EC50 values of 2.7 μg/ml and 3.7 μg/ml, respectively, equivalent to 10 and 17 μm. The results indicate that furanocoumarins account for most of the antiproliferative activity of the tincture.


1998 ◽  
Vol 31 (10) ◽  
pp. 2181-2181
Author(s):  
Yukihiko Hashimoto ◽  
Haruhiko Inufusa ◽  
Toshiyuki Adachi ◽  
Sadao Funai ◽  
Tsukasa Wakano ◽  
...  

Biotherapy ◽  
1993 ◽  
Vol 6 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Hiroyuki Kawami ◽  
Kazuhiro Yoshida ◽  
Yoshiyuki Yamaguchi ◽  
Toshiaki Saeki ◽  
Tetsuya Toge

2001 ◽  
Vol 120 (5) ◽  
pp. A336-A336
Author(s):  
M SHIMADA ◽  
A ANDOH ◽  
Y ARAKI ◽  
Y FUJIYAMA ◽  
T BAMBA

2006 ◽  
Vol 175 (4S) ◽  
pp. 201-201 ◽  
Author(s):  
Isao Hara ◽  
Junya Furukawa ◽  
Kazuki Yamanaka ◽  
Yuji Yamada ◽  
Masato Fujisawa

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