A review on the relationship of mast cells and macrophages in breast cancer — Can herbs or natural products facilitate their anti-tumor effects?

2020 ◽  
pp. 105321
Author(s):  
Leilei Gou ◽  
Grace Gar-Lee Yue ◽  
Pema Tenzin Puno ◽  
Clara Bik-San Lau
Author(s):  
J.R. Pfeiffer ◽  
J.C. Seagrave ◽  
C. Wofsy ◽  
J.M. Oliver

In RBL-2H3 rat leukemic mast cells, crosslinking IgE-receptor complexes with anti-IgE antibody leads to degranulation. Receptor crosslinking also stimulates the redistribution of receptors on the cell surface, a process that can be observed by labeling the anti-IgE with 15 nm protein A-gold particles as described in Stump et al. (1989), followed by back-scattered electron imaging (BEI) in the scanning electron microscope. We report that anti-IgE binding stimulates the redistribution of IgE-receptor complexes at 37“C from a dispersed topography (singlets and doublets; S/D) to distributions dominated sequentially by short chains, small clusters and large aggregates of crosslinked receptors. These patterns can be observed (Figure 1), quantified (Figure 2) and analyzed statistically. Cells incubated with 1 μg/ml anti-IgE, a concentration that stimulates maximum net secretion, redistribute receptors as far as chains and small clusters during a 15 min incubation period. At 3 and 10 μg/ml anti-IgE, net secretion is reduced and the majority of receptors redistribute rapidly into clusters and large aggregates.


2021 ◽  
pp. 1-5
Author(s):  
Ayu Ratuati Setiawan ◽  
Feny Tunjungsari ◽  
Mochamad Aleq Sander

BACKGROUND: Cancer is a disease caused by abnormal growth of body cells that turn malignant and continue to grow uncontrollably. One of the treatments for breast cancer is mastectomy. The quickness of decision-making determines the survival rate of prognosis patients. OBJECTIVE: This study aimed to determine the relationship of self-acceptance with decision-making duration in cancer patients to perform a mastectomy. METHODS: An analytic observation method with cross-sectional design. The samples were taken by purposive sampling method with 50 samples of breast cancer patients. Data collected include age, last level of education, marital status, profession, stage of cancer during mastectomy, self-acceptance score, and decision-making duration to perform a mastectomy. RESULTS: The data analyzed with the Kruskal–Wallis test. The test showed the relationship of self-acceptance (p = 0.027) with decision-making duration in breast cancer patients to perform a mastectomy. CONCLUSION: In Conclusion, there is a relationship of self-acceptance with decision-making duration in breast cancer patients to perform a mastectomy.


Surgery Today ◽  
1992 ◽  
Vol 22 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Atsuo Tsuchiya ◽  
Mitsuhiro Nihei ◽  
Yoshiro Ando ◽  
Shinichi Suzuki ◽  
Izo Kimijima ◽  
...  

2018 ◽  
Vol 19 (4) ◽  
pp. 348-353
Author(s):  
Christina Kudach ◽  
Colleen Dunwoody ◽  
Susan Wesmiller

1992 ◽  
Vol 45 (5) ◽  
pp. 473-485 ◽  
Author(s):  
Patricia A. Ganz ◽  
J.Jack Lee ◽  
Myung-Shin Sim ◽  
Margaret L. Polinsky ◽  
C.Anne Coscarelli Schag

2019 ◽  
Vol 235 ◽  
pp. 181-189
Author(s):  
Sarah Rayne ◽  
Kathryn Schnippel ◽  
Surbhi Grover ◽  
Kirstin Fearnhead ◽  
Deirdre Kruger ◽  
...  

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