In vitro synergic efficacy of the combination of Nystatin with the essential oils of Origanum vulgare and Pelargonium graveolens against some Candida species

Phytomedicine ◽  
2009 ◽  
Vol 16 (10) ◽  
pp. 972-975 ◽  
Author(s):  
Antonio Rosato ◽  
Cesare Vitali ◽  
Monica Piarulli ◽  
Manuela Mazzotta ◽  
Maria Pia Argentieri ◽  
...  
Keyword(s):  
Essential Oils ◽  
Candida Species ◽  
Origanum Vulgare ◽  
Pelargonium Graveolens

In vitro anthelmintic activity of Pimienta dioica and Origanum vulgare essential oils on gastrointestinal nematodes from sheep and cattle

2021 ◽  
Author(s):  
Gerardo Jiménez-Penago ◽  
Roberto González-Garduño ◽  
Luciano Martínez-Bolaños ◽  
Ema Maldonado-Siman ◽  
Alvar A. Cruz-Tamayo ◽  
...  
Keyword(s):  
Essential Oils ◽  
Anthelmintic Activity ◽  
Gastrointestinal Nematodes ◽  
Origanum Vulgare

scholarly journals Chemical Characterization and Antidiabetic Activity of Essential Oils from Pelargonium graveolens Leaves

2021 ◽  
Vol 9 (1) ◽  
pp. 109-113
Author(s):  
Javed Ahamad ◽  
Subasini Uthirapathy
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Chemical Constituents ◽  
Chemical Characterization ◽  
Study Finding ◽  
Antidiabetic Activity ◽  
Chemical Components ◽  
Diabetic Patients ◽  
Pelargonium Graveolens

Pelargonium graveolens (Geranium) is a source of the finest quality of fragrance and its essential oils are used as antibacterial, and antifungal agents. The aim of the current research is to determine chemical constituents in the essential oil of P. graveolens by GC-MS and evaluate its antidiabetic activity via α-glucosidase inhibition assay. The chemical composition of P. graveolens essential oil was determined by GC/MS and its antidiabetic activity was assessed through inhibition of α-glucosidase enzyme in in-vitro models. GC-MS analysis determines 36 chemical components in the essential oil of P. graveolens leaves, and citronellyl isovalerate (10.41 %), menthol (9.61 %), linalool (8.63 %), p-menthone (6.31 %), and geranyl tiglate (4.99 %) were recorded as major constituents. The essential oil of P. graveolens leaves showed concentration dependant inhibition of α-glucosidase enzyme ranging from 28.13±1.41 to 74.24±2.53 µg/mL for concentration ranging from 31.25 to 1000 µg/mL. The IC50 values for of P. graveolens and acarbose were found as 93.72±4.76 and 80.4±2.17 µg/mL, respectively against the α-glucosidase enzyme. The study finding explores the chemical components of P. graveolens growing in the Iraqi Kurdistan region and scientifically supported its possible use in diabetic patients for controlling postprandial hyperglycemia.

scholarly journals Modulatory effect of Syzygium aromaticum and Pelargonium graveolens on oxidative stress and inflammation

2018 ◽  
Author(s):  
Ilias Marmouzi ◽  
El Mostafa Karym ◽  
Rachid Alami ◽  
Meryem El Jemli ◽  
Mourad Kharbach ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Essential Oils ◽  
Toxic Effect ◽  
Tetrahymena Pyriformis ◽  
Syzygium Aromaticum ◽  
Minimal Risk ◽  
Pelargonium Graveolens ◽  
Anti Inflammatory

AbstractBackgroundTherapy combination is defined as disease treatment with two or more medication to acheive efficacy with lower doses or lower toxicity. Regarding its reported toxicities and efficacy, the Essential Oils (EOs) from Syzygium aromaticum (SA) and Pelargonium graveolens (PG) were combined for in vitro and in vivo assays and toxicities.MethodsThe Essential Oils and mixture were tested for in vivo/in vitro antioxidant and anti-inflammatory activities. The assays included the animal model of acute inflammation (carrageenan model), the protective effect on H2O2/Sodium nitroprissude induced stress in Tetrahymena pyriformis, and the in vitro antioxidant assays.ResultsThe chemical analysis of the investigated Oils has lead to the identification of Eugenol (74.06%), Caryophyllene (11.52%) and Carvacrol acetate (7.82%) as the major element in SA; while PG was much higher in Citronellol (30.77%), 10-epi-γ-Eudesmol (22.59%), and Geraniol (13.95%). In our pharmacological screening of samples, both Oils demonstrated good antioxidant effects. In vivo investigation of the antioxidant activity in the protozoa model (T. pyriformis) demonstrated a lesser toxic effect of EOs mixture with no significant differences when oxidative stress markers and antioxidant enzymes (MDA, SOD and CAT) were evaluated. On the other hand the in vivo model of inflammatory response to carrageenan demonstrated a good inhibitory potential of both EOs. The EOs Mixture demonstrated equivalent bioactivity with lower toxic effect and minimal risk for each compound.ConclusionsThe results from this study indicate that EOs mixture from SA and PG demonstrated promising modulatory antioxidant/anti-inflammatory effect, which suggest an efficient association for therapy.

In vitro compatibility of Pimpinella anisum and Origanum vulgare essential oils with nematophagous fungi and their effects against Nacobbus aberrans

2020 ◽  
Vol 93 (4) ◽  
pp. 1381-1395
Author(s):  
Ana Laura Sosa ◽  
Natalia Soledad Girardi ◽  
Laura Cristina Rosso ◽  
Fabricio Salusso ◽  
Miriam Graciela Etcheverry ◽  
...  
Keyword(s):  
Essential Oils ◽  
Nematophagous Fungi ◽  
Origanum Vulgare ◽  
Pimpinella Anisum ◽  
Nacobbus Aberrans

scholarly journals Essential oils against Candida spp: in vitro antifungal activity of Origanum vulgare

2013 ◽  
Vol 7 (20) ◽  
pp. 2245-2250 ◽  
Author(s):  
Brum Cleff Marlete ◽  
Madrid Isabel ◽  
Raquel Meinerz Ana ◽  
Carlos Arauacute jo Meireles Maacute rio ◽  
Roberto Braga de Mello Joatilde o ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Essential Oils ◽  
Origanum Vulgare ◽  
Candida Spp ◽  
In Vitro Antifungal Activity

scholarly journals Efficacy and residual effect of Illicium verum (star anise) and Pelargonium graveolens (rose geranium) essential oil on cat fleas Ctenocephalides felis felis

2021 ◽  
Vol 30 (4) ◽  
Author(s):  
Juliana Pereira Freitas ◽  
Ingrid Lins Raquel de Jesus ◽  
Jéssica Karoline de Oliveira Chaves ◽  
Isabela Scalioni Gijsen ◽  
Diefrey Ribeiro Campos ◽  
...  
Keyword(s):  
Essential Oils ◽  
Insecticidal Activity ◽  
Residual Effect ◽  
Ctenocephalides Felis ◽  
Major Constituent ◽  
Pelargonium Graveolens ◽  
Ctenocephalides Felis Felis ◽  
Star Anise ◽  
Illicium Verum

Abstract The essential oils (EOs) of Illicium verum and Pelargonium graveolens were evaluated for lethality, inhibition of development and residual efficacy against the flea Ctenocephalides felis felis. Their chemical composition was characterized by means of gas chromatography with a flame ionization and mass spectrometry detection. Mortality at different immature stages and among adult fleas was measured through in vitro filter paper tests at different concentrations of EOs. The chemical characterization of I. verum volatile oil showed that E-anethole (79.96%) was the major constituent, while the major compounds in P. graveolens were citronellol (29.67%) and geraniol (14.85%). Insecticidal activity against both immature and adult flea stages were observed. The EO of I. verum had insecticidal activity for approximately 18 days, while the EO activity of P. graveolens lasted for 13 days. The pulicidal activity of I. verum remained above 70% for up to 9 days, while the activity of P. graveolens was 41.7% for up to 2 days. Essential oils, especially that of I. verum, showed insecticidal activity for flea control at different life cycle stages and have potential for the development of ectoparasiticides (biopesticides) for veterinary use.

scholarly journals Corrigendum: Stojkovic D, Glamoclija J, Ciric A, Nikolic M, Ristic M, Siljegovic J, Sokovic M. Investigation on antibacterial synergism of Origanum vulgare and Thymus vulgaris essential oils. Arch biol sci. 2013;65(2):639-43. DOI: 10.2298/ABS1302639S

2015 ◽  
Vol 67 (4) ◽  
pp. 1441-1441
Author(s):  
E Editorial
Keyword(s):  
Essential Oils ◽  
In Vitro Model ◽  
Medicinal Herbs ◽  
Thymus Vulgaris ◽  
Antibacterial Effects ◽  
Origanum Vulgare ◽  
Vitro Model ◽  
Font Color

The authors of the above-referenced article have requested a corrigendum to it. The article should include the following reference: Sokovic, M., Glamoclija, J., Marin, D.P., Brkic, D., and L. J. L. D. van Griensven (2010) Antibacterial Effects of the Essential Oils of Commonly Consumed Medicinal Herbs Using an In Vitro Model. Molecules. 15(11), 7532-7546. <br><br><font color="red"><b> Link to the corrected article <u><a href="http://dx.doi.org/10.2298/ABS1302639S">10.2298/ABS1302639S</a></b></u>

scholarly journals In vitro Inhibitory Action of the Essential Oils of Origanum Vulgare and Rosmarinus Officinalis against Aspergillus Fumigatus

2021 ◽  
Vol 8 (03) ◽  
pp. e143-e152
Author(s):  
Antonia Carolina Melo Monteiro ◽  
Aminata Doucoure Drame ◽  
Francisca Melo Nascimento ◽  
Ana Luisa Miranda-Vilela ◽  
Alexandre Vasconcelos Lima ◽  
...  
Keyword(s):  
Essential Oils ◽  
Aspergillus Fumigatus ◽  
Inhibitory Action ◽  
Rosmarinus Officinalis ◽  
Disk Diffusion ◽  
In Vivo Studies ◽  
Origanum Vulgare ◽  
Agar Dilution

Abstract Aspergillus fumigatus is the main etiological agent of aspergillosis. Considering azole antifungal drug resistance in A. fumigatus, which compromises treatment, new alternatives are needed. Among them, essential oils (EOs) can be an alternative treatment, having shown positive results in inhibiting phytopathogenic fungi in vitro. We aimed to determine the in vitro antifungal activity of Origanum vulgare L. subsp. hirtum (Link) (oregano) and Rosmarinus officinalis L. (rosemary) EOs alone and in association (O. vulgare+R. officinalis) against A. fumigatus. EOs were analyzed by gas chromatography (GC-FID and GC/MS systems), and analyses showed that the major components of O. vulgare EO were carvacrol (67.8%), p-cymene (14.8%), and thymol (3.9%); for R. officinalis, they were the monoterpenes 1,8-cineole (49.1%), camphor (18.1%) and α-pinene (8.1). For biological assays, five EO concentrations, 0.2; 0.4; 0.6; 0.8 and 1.0%, were used in disk diffusion and agar dilution tests for 21 days. In disk diffusion, O. vulgare EO alone and in association (O. vulgare+R. officinalis) showed fungicidal activity at all concentrations. In agar dilution, inhibitory action was demonstrated from 0.6% for O. vulgare EO and in association (O. vulgare+R. officinalis). R. officinalis EO at 1.0% showed no fungal growth, determining the minimum inhibitory concentration (MIC). The present study demonstrated inhibitory actions of O. vulgare and R. officinalis EOs in A. fumigatus. GC analyses corroborated the literature regarding their antibacterial and antifungal effects. However, further in vitro and in vivo studies are needed to evaluate EOs as alternative antifungals for treating aspergillosis.

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