Effects of testosterone on cognition in young adult male rhesus monkeys

2009 ◽  
Vol 98 (5) ◽  
pp. 524-531 ◽  
Author(s):  
Agnès Lacreuse ◽  
Margaret R. Chiavetta ◽  
Ashley-Ann C. Shirai ◽  
Jerrold S. Meyer ◽  
Daniel R. Grow
1973 ◽  
Vol 7 (3) ◽  
pp. 297-303 ◽  
Author(s):  
G. J. Wolcott ◽  
J. A. Valentine ◽  
R. D. Cebul

20 healthy young adult male rhesus monkeys were bled 3 times a week in an attempt to induce an anaemia and a depletion of iron stores. A mean haemoglobin of 6·1 g/100 ml and a haematocrit of 23% were obtained by 30 days. The iron saturation had fallen to a level of 11% and the reticulocyte response to 4·6%. Of note was the short period required to induce these haematological changes, and the minimal impact on the animals.


2021 ◽  
Vol 22 ◽  
pp. 100975
Author(s):  
Ellen Duncan ◽  
Suneet Bhansali ◽  
Ee Tein Tay

Author(s):  
Asma Alonazi ◽  
Shahnaz Hasan ◽  
Shahnawaz Anwer ◽  
Azfar Jamal ◽  
Suhel Parvez ◽  
...  

This study compares the effects of electromyographic-biofeedback (EMG-BF)-guided isometric quadriceps strengthening with patellar taping and isometric exercise alone in patellofemoral pain syndrome (PFPS) among young adult male athletes. Sixty young adult male athletes with PFPS participated in the study. Participants were randomly divided into two groups: (1) EMG-BF-guided isometric exercise training with patellar taping (experimental group, n = 30), and (2) sham EMG-BF training with an isometric exercise program (control group, n = 30). Participants conducted their respective exercise programs for five days per week across four weeks. Study outcomes were pain (measured by the visual analog scale), functional disability (measured by the Kujala Anterior Knee Pain scale), and quadriceps strength (measured by an ISOMOVE dynamometer). Measurements were taken at baseline, Week 2, Week 4, and during a follow-up at Week 6. The experimental group demonstrated significantly lower VAS score at Weeks 2 and 4 compared to that of the control group (p = 0.008 and 0.0005, respectively). The score remained significantly lower at the Week 6 follow-up compared to the control group (p = 0.0005). There were no differences in knee function at Weeks 2 and 4 between the two groups (p = 0.086 and 0.171, respectively); however, the experimental group showed significantly better knee function at Week 6 compared to the control group (p = 0.002). There were no differences in quadriceps strength at Week 2 between the two groups (p = 0.259); however, the experimental group demonstrated significantly higher quadriceps strength at Weeks 4 and 6 compared to the control group (p = 0.0008). Four weeks of EMG-BF supplementation training with patellar taping demonstrated significant improvements in pain intensity, functional disability, and quadriceps muscle strength in young adult male athletes with PFPS.


1966 ◽  
Vol 9 (2) ◽  
pp. 194-207 ◽  
Author(s):  
Eugene B. Cooper

Interrelationships among client progress in stuttering therapy, the nature of the affect interchange between client and clinician, and certain personality characteristics of both client and clinician were studied. Sixteen young adult male stutterers and their 11 graduate student clinicians served as subjects. Results support observations that the clinicians' and clients' personalities are significant variables in the stuttering therapy situation, support observations that important similarities exist between stuttering therapy and psychotherapy, and suggest that it is more accurate to note stages in the therapeutic relationship, rather than to characterize the relationship as if it were the same throughout therapy.


2013 ◽  
Vol 229 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Emily E. Roguski ◽  
Hao Chen ◽  
Burt M. Sharp ◽  
Shannon G. Matta

1980 ◽  
Vol 93 (3) ◽  
pp. 287-293 ◽  
Author(s):  
E. Jean Wickings ◽  
E. Nieschlag

Abstract. Adult male rhesus monkeys are aggressive animals and very difficult to handle. Hence experimental manipulations necessarily involve the use of restraint procedures, either chemical or physical, which may influence endocrine functions. Therefore, the effects of ketamine anaesthesia on basal hormone levels and on the pituitary response to LRH and TRH were investigated in 4 adult male rhesus monkeys. Values were compared to those obtained from the same animals restrained in primate chairs for approximately 48 h, a procedure to which they had been accustomed to over the preceding 6 months. Serum cortisol levels under anaesthesia were at all times lower than in conscious monkeys, but increased after 2 h to values twice as high as measured initially. Serum testosterone concentrations were not significantly different on the two occasions, but levels under anaesthesia were slightly higher initially than in the conscious monkeys, and decreased gradually over the 3 h test period. Initial prolactin levels were lower in the anaesthetized monkeys, and increased 2–3-fold after 90 min; values at 3 h were not significantly different from those in conscious monkeys. Intravenous TRH elicited a similar response in prolactin on both occasions, maximum values occurring after 15–30 min and returning to basal levels after 3 h. The maximum values attained and the area under the response curves were higher under anaesthesia. LRH stimulation resulted in a 15- and 30-fold increase in serum levels of biologically active LH, with and without anaesthesia, respectively. Basal levels were not significantly different on the two occasions. The area under the LH response curve was higher in 3 of the 4 monkeys without anaesthesia. The extent to which results in conscious monkeys are affected by stress is difficult to assess. Since neither handling technique allows for the collection of 'true' basal data, it is paramount to standardize and define the conditions under which experiments, and even routine blood sampling, are performed in male rhesus monkeys.


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