Progressive circuit resistance training improves inflammatory biomarkers and insulin resistance in obese men

Objective: The overweight-related health problems among adolescents are obvious. Resistance training is recognized as a safe and efficacious exercise modality to have health-promoting effects in overweight adolescents. This study aimed to assess the efficacy of circuit resistance training (CRT) in improving inflammatory status, insulin resistance and body composition in overweight male adolescents. Materials and Methods: Twenty overweight adolescent boys (aged: 18.5 (±1), weight: 81.1 (±4.5), body mass index: 27.7 (±0.7)) completed this study. The participants were randomly and equally divided into two groups of control (CG; n=10) and circuit resistance training (CRT; n=10). The CG did their daily routine activities and the CRT group performed its training protocol 3 days a week for 6 weeks. Body composition components and serum variables were measured a day before and after the study. Insulin resistance index was measured by HOMA-IR. Results: The subjects in the CG showed significantly increased changes compared with pre-training values. Moreover, significant changes were found fort the changes of BW ( P -value= 0.005), BMI ( P -value= 0.001) and BF% ( P -value= 0.003) between groups. Conclusion: This study suggested that although six weeks of CRT failed to induce meaningful anti-inflammatory cytokine responses, and to improve body composition and HOMA-IR in overweight adolescent boys, but had protective effects on inflammatory status, HOMA-IR and body composition and prevented them from being deteriorated

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The Effect of Circuit Resistance Training on Plasma Levels of Amino acids, Alpha-hydroxybutyrate, Mannose, and Urinary Levels of Glycine Conjugated Adducts in Obese Adolescent Boys

Applied Physiology Nutrition and Metabolism ◽

10.1139/apnm-2020-0171 ◽

2020 ◽

Author(s):

Seyed Ali Rasooli ◽

Rozita Fathi ◽

Farhad Ahmadi-Kani Golzar ◽

Masoumeh Baghersalimi

Keyword(s):

Insulin Resistance ◽

Amino Acids ◽

Resistance Training ◽

Plasma Levels ◽

Control Group ◽

Adolescent Boys ◽

Obese Adolescent ◽

Urinary Levels ◽

Circuit Resistance Training ◽

Circuit Resistance

Few studies have examined the improving effects of exercise on the association between metabolites of impaired protein metabolism and insulin resistance in obese children. Therefore, this study aims to investigate the effect of circuit resistance training (CRT) on plasma levels of amino acids, alpha-hydroxybutyrate (α-HB), mannose, and urinary levels of glycine conjugated adducts in obese adolescent boys. Forty obese adolescent boys (BMI above the 95th percentile) with an age range of 14-17 were randomly divided into CRT group (n= 20) and control group (n= 20). The CRT program (3 times/week, 70-80% of 1 repetition maximum) was performed for 8 weeks. The results indicated that the body composition and plasma levels of glucose, insulin resistance, valine, mannose, lysine and the sum of branched-chain amino acids (BCAAs) were decreased due to CRT. The plasma levels of asparagine, glycine, serine, and urinary levels of glycine conjugated adduct also increased in the CRT group. Although α-HB level decreased during CRT, it had no significant difference from that of the control group. It can be concluded that the improvement in obesity complications including insulin resistance in obese adolescent boys after CRT may be due to decrease in plasma levels of mannose and BCAAs and increase urinary metabolites. Novelty Bullets: • CRT improves glucose metabolism and insulin resistance in obese adolescent boys. • CRT decreases plasma levels of mannose and BCAAs and normalizes other amino acids. • CRT increases urinary levels of glycine conjugated adducts.

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The effects of circuit resistance training on plasma progranulin level, insulin resistance and body composition in obese men

Hormone Molecular Biology and Clinical Investigation ◽

10.1515/hmbci-2019-0050 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Alireza Safarzade ◽

Hamid Alizadeh ◽

Zainab Bastani

Keyword(s):

Insulin Resistance ◽

Body Composition ◽

Resistance Training ◽

Body Mass ◽

Training Session ◽

Training Group ◽

Control Group ◽

Model Assessment ◽

Circuit Resistance Training ◽

Circuit Resistance

AbstractBackgroundProgranulin (PGRN) is implicated in obesity and insulin resistance (IR). The aim of this study was to evaluate the effects of 8 weeks of circuit resistance training (CRT) on plasma PGRN, IR and body composition in obese men.Materials and methodsTwenty-eight healthy obese men [age: 36 ± 7.7 years, body weight (BW): 96.4 ± 15.6 kg, body mass index (BMI): 32.4 ± 4.5 kg/m2] completed the study. Subjects were randomly assigned to two groups of control and training. Subjects in the training group underwent training for 8 weeks, 3 times a week. Blood samples and anthropometric characteristics were taken before the commencement of the exercise protocol and 72 h after the last training session. The homeostatic model assessment of insulin resistance (HOMA-IR) was used to measure IR.ResultsBW, BF%, BMI, waist-hip ratio (WHR), HOMA-IR and plasma PGRN levels except lean body mass (LBM) were significantly reduced in the training group (p < 0.05). Additionally, except for LBM, subjects in the training group had significantly decreased BW, BF%, BMI, WHR, HOMA-IR and plasma PGRN levels compared to changes in those in the control group (p < 0.05). Significant correlations were found between the changes in plasma PGRN and the changes in insulin, HOMA-IR and BMI (p < 0.05).ConclusionsThe findings showed that 8 weeks of CRT improved body composition and IR which were accompanied by reduced plasma PGRN levels. This study suggests that CRT has the potential for obese individuals to counteract obesity-associated health impairments.

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The effect of 12 weeks of circuit resistance training course on some of the inflammatory factors in obese non-alcoholic fatty liver men

Journal of Shahid Sadoughi University of Medical Sciences ◽

10.18502/ssu.v27i1.870 ◽

2019 ◽

Author(s):

Gholamreza Salvand ◽

Masoud Nikbakht ◽

Saeed Shakerian

Keyword(s):

Insulin Resistance ◽

Resistance Training ◽

Fatty Liver ◽

Serum Levels ◽

T Test ◽

Control Group ◽

Alcoholic Fatty Liver ◽

Training Course ◽

Circuit Resistance Training ◽

Circuit Resistance

Introdution: Non-alcoholic fatty liver disease (NFALD) is a disease associated with metabolic syndrome and lifestyle. The purpose of the present study was to investigate the effect of 12 weeks of circuit resistance training course on interleukin-17 (IL-17) levels, 70 kDa thermal shock protein (HSP70), insulin resistance and serum levels of alanine aminotransferase (ALT), as well as aspartate aminotransferase (AST). Method: In this clinical trial study, 30 males with NFALD were selected through targeted sampling and were randomly assigned to one of two groups of practice and control intervention. The training program included 12 weeks of resistive training and 3 training sessions per week, which was performed as periodic circuit resistance training. Before eating breakfast, blood sampling was done one day before the start of training and 3 days after the last training session. For statistical analysis, paired t-test was used to compare intra-group data. Independent t-test was used for comparison between groups. Data were used via the SPSS v 22 software. The significance was defined as P≤0.05. Results: After the training course, compared to the control group a significant decrease was observed in weight (P = 0.008), BMI (P = 0.006), body fat percentage (P <0.001), insulin resistance (P <0.001), HSP70 (P <0.001), IL-17 (P <0.001), serum levels of ALT (P <0.001) and AST (P <0.001) enzymes. Conclusion: Regarding the results of this study, circuit resistance training has an effective role in improving the liver function in NFALD patients by reducing insulin resistance and levels of inflammatory cytokines, this method of resistance training can be useful in the treatment of these patients.

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Home-Based Circuit Resistance Training to Overcome Barriers to Exercise for People With Spinal Cord Injury

Journal of Neurologic Physical Therapy ◽

10.1097/npt.0b013e31829247a9 ◽

2013 ◽

Vol 37 (2) ◽

pp. 65-71 ◽

Cited By ~ 7

Author(s):

Elizabeth Sasso ◽

Deborah Backus

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Resistance Training ◽

Home Based ◽

Cord Injury ◽

Barriers To Exercise ◽

Circuit Resistance Training ◽

Circuit Resistance

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Circuit resistance training improved endothelial dysfunction in obese aged women

Nutrición Hospitalaria ◽

10.20960/nh.17 ◽

2016 ◽

Vol 33 (1) ◽

Author(s):

Ignacio Rosety ◽

María Teresa Pery ◽

Jesús Rosety ◽

Natalia García ◽

María Antonia Rodríguez-Pareja ◽

...

Keyword(s):

Resistance Training ◽

Endothelial Dysfunction ◽

Circuit Resistance Training ◽

Circuit Resistance

Introducción: recientes estudios han confirmado que el entrenamiento de fuerza en circuito podría reducir la masa grasa visceral en mujeres mayores obesas. Para seguir avanzando en esta línea de trabajo, nos propusimos determinar su impacto en marcadores de disfunción endotelial.Material y método: participaron voluntariamente 48 mujeres (70-75 años) con obesidad procedentes de la comunidad. De ellas, 24 fueron asignadas aleatoriamente al grupo experimental para desarrollar un programa de entrenamiento de fuerza en circuito de 6 estaciones durante 12 semanas con 3 sesiones/semana. Los marcadores de disfunción endotelial ensayados fueron: endotelina-1, molécula de adhesión intercelular-1 (ICAM-1) y molécula de citoadhesión vascular-1 (VCAM-1). Asimismo se evaluó su influencia en un test funcional para población mayor como el de sentarse levantarse en 30 segundos. Este protocolo fue aprobado por un comité de ética institucional. Resultados: tras completar el programa de intervención se observó un descenso significativo de los niveles plasmáticos de entotelina-1 (2,28 ± 0,7 vs. 1,98 ± 1,1 pg/ml; p = 0,019; d = 0,67) e ICAM-1 (290 ± 69 vs. 255 ± 76 ng/ml; p = 0,004; d = 0,92). También mejoró significativamente la puntuación del test funcional (18,7 ± 3,1 vs. 23,0 ± 3,6 repeticiones; p = 0,019; d = 0,98). Por el contrario, no se observaron cambios en el grupo control.Conclusión: el entrenamiento de fuerza en circuito mejora la disfunción endotelial presente en mujeres mayores obesas. Futuros estudios siguen siendo necesarios para consolidar su aplicación en clínica.

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