scholarly journals Agaricus blazei Murrill Mushroom: A Review on the Prevention and Treatment of Cancer

Author(s):  
Amanda Gollo Bertollo ◽  
Maiqueli Eduarda Dama Mingoti ◽  
Marcos Eduardo Plissari ◽  
Graciele Betti ◽  
Walter Antônio Roman Junior ◽  
...  
2019 ◽  
pp. 46-49
Author(s):  
Xiang Li Pei Xu ◽  
Wen-Quan Huang ◽  
Rui Li

Agaricus blazei Murill (ABM) also known as Brazilian mushroom, originated in Brazil and Peru, is a kind of edible and medicinal fungus. It is neutral in nature and sweet in taste, distributed in heart, lung, liver and kidney channels. It has high nutritional value and medical efficacy and is rich in protein, polysaccharides, vitamins, minerals and unsaturated fatty acids. Its pharmacological ingredients mainly include nucleic acid, exogenous lectin, sterols, fatty acids and polysaccharides. It also has the effect of anti-cancer, anti-tumor, immune regulation, anti-inflammatory activity, protection of liver and kidney, treatment of diabetes, antioxidant activity, anti-fatigue effect, prevention and treatment of leukemia, asthma, and radiation injury. It can strengthen health and promote hematopoiesis. With the improvement of people’s living standards and the advancement of science and technology, many diseases already have better treatments and the average life expectancy is greatly extended. With the development of food industry, medicine and other related industries, some foods with unique medicinal effects and values such as glossy ganoderma, cordyceps sinensis and Agaricus blazei Murill have been re-recognized and used. The use of these pharmacological foods for disease prevention and treatment has become a trend. For example, the nutrients of relevant foods are extracted to make health-care products and patients are given corresponding solution to assist their treatments. Some progress has been made in realizing the pharmacological effects and dietary applications of Agaricus blazei Murill. This paper will analyze and summarize the results of current researches of pharmacological effect and application in dietotherapy of Agaricus blazei Murill, which is helpful to improve people’s understanding of its medicinal effects and to provide rich experience in dietary therapy and experimental basis. With the further research on the pharmacological effects of Agaricus blazei Murill, it will be more widely used in food therapy.


1989 ◽  
Vol 20 (1) ◽  
pp. 102-107 ◽  
Author(s):  
Joel C. Kahane ◽  
Robert Mayo

In this paper we argue for the aggressive management of voice disorders. Aggressive management includes early identification, prevention, and treatment of voice disorders. The argument for aggressive management is supported by current incidence trends, laryngologists' expectations, and the benefits of prevention programs.


1998 ◽  
Vol 1 (5) ◽  
pp. 166-174 ◽  
Author(s):  
Evelyn R Hermes De Santis ◽  
Betsy S Laumeister ◽  
Vidhu Bansal ◽  
Vandana Kataria ◽  
Preeti Loomba ◽  
...  

2004 ◽  
Vol 74 (1) ◽  
pp. 74-85 ◽  
Author(s):  
Liu ◽  
Russell ◽  
Smith ◽  
Bronson ◽  
Milbury ◽  
...  

Because reactive oxygen species have been implicated as mediators of inflammatory bowel disease (IBD), we evaluated the potential preventive and therapeutic effects of two dietary antioxidants, glutathione (GSH) and coenzyme Q10 (CoQ10) on dextran sulfate sodium (DSS)-induced colitis in mice. Fifty female 8-wk old Swiss-Webster mice were randomly assigned to 4 groups for a pre-treatment 'prevention' study: (1) GSH (1% of diet); (2) CoQ10 (200 mg/kg/d); (3) DSS only (3% of drinking water); (4) control (no treatment). The mice in groups 1 and 2 were fed with GSH or CoQ10 for 21 wks, and the mice in groups 1, 2 and 3 were provided DSS from wk 7 for 4 cycles (1 cycle = 1 wk DSS followed by 2-wk water). Another 50 mice were randomly assigned to 4 groups for a 21-wk 'treatment' study where the mice in groups 1, 2, and 3 were administered DSS for 6 cycles (18 wks) to induce colitis. GSH and CoQ10 were added from wk 7 until the completion of the protocol. Loose stools and hemocult positivity were modestly but significantly reduced with GSH or CoQ10 at several periods during the intervention in both the prevention and treatment studies. In contrast, histological evaluation revealed increases in colonic dysplasia and ulceration with GSH or CoQ10. Thus, in this mouse model, GSH and CoQ10 appear to have a beneficial effect on acute signs of IBD, but may have an adverse impact on the chronic pathophysiology of the disease. Further studies using additional animal models are required to determine whether GSH or CoQ10 provide a favorable or unfavorable benefit:risk ratio in the prevention or treatment of IBD.


Author(s):  
Bernd Schulte ◽  
Christina Lindemann ◽  
Angela Buchholz ◽  
Anke Rosahl ◽  
Martin Härter ◽  
...  

Abstract. Background: The German Guideline on Screening, Diagnosis and Treatment of Alcohol Use Disorders aims to increase the uptake of evidence-based interventions for the early identification, diagnosis, prevention and treatment of alcohol-related disorders in relevant healthcare settings. To date, dissemination has not been accompanied by a guideline implementation strategy. The aim of this study is to develop tailored guideline implementation strategies and to field-test these in relevant medical and psycho-social settings in the city of Bremen, Germany. Methods: The study will conduct an impact and needs assessment of healthcare provision for alcohol use orders in Bremen, drawing on a range of secondary and primary data to: evaluate existing healthcare services; model the potential impact of improved care on public health outcomes; and identify potential barriers and facilitators to implementing evidence-based guidelines. Community advisory boards will be established for the selection of single-component or multi-faceted guideline implementation strategies. The tailoring approach considers guideline, provider and organizational factors shaping implementation. In field tests quality outcome indicators of the delivery of evidence-based interventions will be evaluated accompanied by a process evaluation to examine patient, provider and organizational factors. Outlook: This project will support the translation of guideline recommendations for the identification, prevention and treatment of AUD in routine practice and therefore contributes to the reduction of alcohol-related burden in Germany. The project is running since October 2017 and will provide its main outcomes by end of 2020. Project results will be published in scientific journals and presented at national and international conferences.


Sign in / Sign up

Export Citation Format

Share Document