scholarly journals The relationship of DSM-IV pathological gambling to compulsive buying and other possible spectrum disorders: Results from the Iowa PG family study

2015 ◽  
Vol 226 (1) ◽  
pp. 273-276 ◽  
Author(s):  
Donald W. Black ◽  
William Coryell ◽  
Raymond Crowe ◽  
Martha Shaw ◽  
Brett McCormick ◽  
...  
Keyword(s):  
Pathological Gambling ◽  
Family Study ◽  
Compulsive Buying ◽  
Dsm Iv ◽  
Spectrum Disorders ◽  
Relationship Of ◽  
The Relationship

The relationship of obsessive–compulsive disorder to possible spectrum disorders: results from a family study

2000 ◽  
Vol 48 (4) ◽  
pp. 287-293 ◽  
Author(s):  
O.Joseph Bienvenu ◽  
Jack F Samuels ◽  
Mark A Riddle ◽  
Rudolf Hoehn-Saric ◽  
Kung-Yee Liang ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Family Study ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Spectrum Disorders ◽  
Relationship Of ◽  
The Relationship

scholarly journals Autism Profiles of Males With Fragile X Syndrome

2008 ◽  
Vol 113 (6) ◽  
pp. 427-438 ◽  
Author(s):  
Susan W. Harris ◽  
David Hessl ◽  
Beth Goodlin-Jones ◽  
Jessica Ferranti ◽  
Susan Bacalman ◽  
...  
Keyword(s):  
Fragile X Syndrome ◽  
Fragile X ◽  
Autism Diagnosis ◽  
Cgg Repeat ◽  
Molecular Features ◽  
Fmr1 Mrna ◽  
Two Measures ◽  
Dsm Iv ◽  
Relationship Of ◽  
The Relationship

Abstract Autism, which is common in individuals with fragile X syndrome, is often difficult to diagnose. We compared the diagnostic classifications of two measures for autism diagnosis, the ADOS and the ADI-R, in addition to the DSM-IV-TR in 63 males with this syndrome. Overall, 30% of the subjects met criteria for autistic disorder and 30% met criteria for PDD-NOS. The classifications on the ADOS and DSM-IV-TR were most similar, whereas the ADI-R classified subjects as autistic much more frequently. We further investigated the relationship of both FMRP and FMR1 mRNA to symptoms of autism in this cohort and found no significant relationship between the measures of autism and molecular features, including FMRP, FMR1 mRNA, and CGG repeat number.

scholarly journals Hemoglobin L Ferrara in a Jewish Family Associated with a Hemolytic State in the Propositus

Blood ◽  
1969 ◽  
Vol 34 (2) ◽  
pp. 157-165 ◽  
Author(s):  
RONALD L. NAGEL ◽  
HELEN M. RANNEY ◽  
THOMAS B. BRADLEY ◽  
ALAN JACOBS ◽  
LINDA UDEM
Keyword(s):  
Family Study ◽  
Simultaneous Occurrence ◽  
Red Cell ◽  
Jewish Family ◽  
Sh Groups ◽  
Red Cell Enzymes ◽  
Abnormal Hemoglobin ◽  
Relationship Of ◽  
The Relationship ◽  
Cell Defect

Abstract A Jewish family in which Hb L Ferrara (α247 Asp → Gly β2) occurred is reported. Studies of some of the properties of this hemoglobin demonstrated that its oxygen equilibria, number of readily reactive-SH groups, and spectro-photometric tyrosine titration were indistinguishable from Hb A. Nevertheless, Hb LF was more unstable than Hb A at 55 C. The propositus had accelerated blood destruction although six other heterozygotes for Hb LF did not. A second defect in red cell enzymes or red cell lipids of the propositus was not demonstrable with the technics used but the possibility that the simultaneous occurrence of Hb LF and an otherwise "silent" red cell defect may lead to a hemolytic state remains an attractive explanation. The data provided by this family study did not permit a definite conclusion about the relationship of clinically evident hemolysis in the propositus to the presence of the abnormal hemoglobin.

scholarly journals The relationship of DSM-IV personality disorders to nicotine dependence-results from a national survey

2010 ◽  
Vol 108 (1-2) ◽  
pp. 141-145 ◽  
Author(s):  
Attila J. Pulay ◽  
Frederick S. Stinson ◽  
W. June Ruan ◽  
Sharon M. Smith ◽  
Roger P. Pickering ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Nicotine Dependence ◽  
National Survey ◽  
Dsm Iv ◽  
Relationship Of ◽  
The Relationship

The relationship of personality traits to substance abuse in patients with bipolar disorder

2007 ◽  
Vol 22 (5) ◽  
pp. 305-308 ◽  
Author(s):  
Gonzalo Haro ◽  
Joseph R. Calabrese ◽  
Christina Larsson ◽  
Edwin R. Shirley ◽  
Eva Martín ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Substance Abuse ◽  
Personality Traits ◽  
Multinomial Logistic Regression ◽  
Novelty Seeking ◽  
Related Disorder ◽  
History Of ◽  
Dsm Iv ◽  
Relationship Of ◽  
The Relationship

AbstractPurposeThe aim of this study is to determine if personality traits contribute to the likelihood of substance abuse in Bipolar Disorder (BD).Subjects/materials and methodsFifty-nine patients meeting DSM-IV criteria for BD: 20 without any history of Substance Related Disorder (SRD), 21 with a lifetime history of SRD but without current SRD, and 18 with current SRD. Patients filled out the TCI, the differences were analyzed by ANOVA and the likelihood was obtained by Multinomial Logistic Regression.ResultsOnly Novelty Seeking (NS) is statistically different between the groups. Patients with BD with current SRD have higher rates in NS than those with past SRD, and those without a history of SRD. NS was confirmed as a predicting variable, both to current SRD (OR [CI 95%] = 1.039/1.351; p = 0.011) and past SRD (OR [CI 95%] = 1.004/1.277; p = 0.042) on patients with BD.DiscussionThe results shown would appear to confirm the relationship of NS with the SRD, so long as there is no clear evidence that indicates the association of NS with BD.ConclusionsThere appears a greater predisposition to develop SRD in those patients with a higher degree of NS. The use of the Cloninger's TCI could be used in BD to determine the risk of developing an SRD. Early detection might help improve prognosis.

scholarly journals The psychoses: Cluster 3 of the proposed meta-structure for DSM-V and ICD-11

2009 ◽  
Vol 39 (12) ◽  
pp. 2025-2042 ◽  
Author(s):  
W. T. Carpenter ◽  
J. R. Bustillo ◽  
G. K. Thaker ◽  
J. van Os ◽  
R. F. Krueger ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Psychotic Disorders ◽  
Task Force ◽  
Neural Substrates ◽  
Schizotypal Personality ◽  
Dsm V ◽  
Dsm Iv ◽  
Few Data ◽  
Relationship Of ◽  
The Relationship

BackgroundIn an effort to group mental disorders on the basis of etiology, five clusters have been proposed. Here we consider the validity of the cluster comprising selected psychotic and related disorders.MethodA group of diagnostic entities classified under schizophrenia and other psychotic disorders in DSM-IV-TR were assigned to this cluster and the bordering disorders, bipolar (BD) and schizotypal personality disorders (SPD), were included. We then reviewed the literature in relation to 11 validating criteria proposed by the DSM-V Task Force Study Group.ResultsRelevant comparisons on the 11 spectrum criteria are rare for the included disorders except for schizophrenia and the two border conditions, BD and SPD. The core psychosis group is congruent at the level of shared psychotic psychopathology and response to antipsychotic medication. BD and SPD are exceptions in that psychosis is not typical in BD-II disorder and frank psychosis is excluded in SPD. There is modest similarity between schizophrenia and BD relating to risk factors, neural substrates, cognition and endophenotypes, but key differences are noted. There is greater support for a spectrum relationship of SPD and schizophrenia. Antecedent temperament, an important validator for other groupings, has received little empirical study in the various psychotic disorders.ConclusionsThe DSM-IV-TR grouping of psychotic disorders is supported by tradition and shared psychopathology, but few data exist across these diagnoses relating to the 11 spectrum criteria. The case for including BD is modest, and the relationship of BD to other mood disorders is addressed elsewhere. Evidence is stronger for inclusion of SPD, but the relationship with other personality disorders along the 11 criteria is not addressed and the absence of psychosis presents a conceptual problem. There are no data along the 11 spectrum criteria that are decisive for a cluster based on etiology, and inclusion of BD and SPD is questionable.

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