Structural brain alterations in older adults exposed to early-life adversity

2021 ◽  
pp. 105272
Author(s):  
Marie-Laure Ancelin ◽  
Isabelle Carriere ◽  
Sylvaine Artero ◽  
Jerome J Maller ◽  
Chantal Meslin ◽  
...  
2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 924-924
Author(s):  
Janae Briggs ◽  
Stephanie Child

Abstract Early life adversity (ELA) is associated with poor health through social and economic pathways. ELA also shapes cognitive and emotional development, including self-perception, social attachment and mental well-being. As such, ELA may shape later life health through social relationships, yet few studies have examined these associations. Data from the UC Berkeley Social Network Study were used to examine ELA measured retrospectively and current personal network characteristics among young (21-30 years) and older adults (50-70 years). ELA was operationalized as a summary of six experiences occurring before age 18 (e.g., parents’ divorce/separation, violence/drug use in the home, etc.). Personal network characteristics included objective measures, such as the number of ties who provide or receive various types of support, and subjective assessments about the adequacy of support received. Multivariate regression models adjusted for gender, race/ethnicity, and level of education. Among young adults, ELA was associated with more ties who rely upon the ego for support (b=0.15, 95% CI: 0.02, 0.28, p=0.02). Among older adults, ELA was associated with more ties named as either an advisor (b=0.14, 95% CI: 0.04, 0.21, p=0.02) or difficult/demanding (b=0.12, 95% CI: 0.04, 0.21, p<0.01). Furthermore, ELA was associated with less confidence in family support available (b= -0.09, 95% CI: -0.16, -0.03, p<0.01) and fewer emotionally close family members (b= -0.18, 95% CI: -0.32, -0.03, p=0.02) among older adults. In conclusion, clear differences emerged in network characteristics by exposure to ELA, particularly among older adults. The findings highlight potential pathways through which ELA patterns later life health.


2006 ◽  
Vol 33 (S 1) ◽  
Author(s):  
S. Schnaudigel ◽  
C. Preul ◽  
H.J. Mentzel ◽  
O.W. Witte ◽  
M. Tittgemeyer ◽  
...  

2019 ◽  
Author(s):  
Mary Elizabeth Zinn ◽  
Edward Huntley ◽  
Daniel Keating

Introduction. Early life adversity (ELA) can result in negative health-outcomes, including psychopathology. Evidence suggests that adolescence is a critical developmental period for processing ELA. Identity formation, which is crucial to this developmental period, may moderate the effect between ELA and psychopathology. One potential moderating variable associated with identity formation is Prospective Self, a latent construct comprised of future-oriented attitudes and behaviors.Methods. Participants are from the first wave of an ongoing longitudinal study designed to characterize behavioral and cognitive correlates of risk behavior trajectories. A community sample of 10th and 12th grade adolescents (N = 2017, 55% female) were recruited from nine public school districts across eight Southeastern Michigan counties in the United States. Data were collected in schools during school hours or after school via self-report, computer-administered surveys. Structural equation modeling was used in the present study to assess Prospective Self as a latent construct and to evaluate the relationship between ELA, psychopathology, and Prospective Self.Results. Preliminary findings indicated a satisfactory fit for the construct Prospective Self. The predicted negative associations between Prospective Self and psychopathology were found and evidence of moderation was observed for externalizing behavior problems, such that the effects of ELA were lower for individuals with higher levels of Prospective Self. Conclusion. These results support the role of Prospective Self in conferring resilience against externalizing behavior problems associated with ELA among adolescents. Keywords: Adolescence, Adverse Childhood Experiences, Psychopathology, Self-concept, Adolescent Health, Early Life Adversity


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