scholarly journals Two-years persistence of anal high-risk HPV infections in women living with HIV, results from the EVVA study

2018 ◽  
Vol 5 ◽  
pp. S12
Author(s):  
Alexandra de Pokomandy ◽  
Alexandra de Pokomandy ◽  
Bernard Lessard ◽  
Marie-Hélène Mayrand ◽  
Louise Charest ◽  
...  
Keyword(s):  
High Risk ◽  
Women Living With Hiv ◽  
High Risk Hpv ◽  
Living With Hiv

scholarly journals Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Gad Murenzi ◽  
Patrick Tuyisenge ◽  
Faustin Kanyabwisha ◽  
Athanase Munyaneza ◽  
Benjamin Muhoza ◽  
...  
Keyword(s):  
High Risk ◽  
Significant Proportion ◽  
Women Living With Hiv ◽  
Screening Study ◽  
Hpv Types ◽  
The Mean ◽  
Nested Analysis ◽  
High Risk Hpv ◽  
Living With Hiv ◽  
Hrhpv Type

Abstract Background Persistent infection with high-risk human papillomavirus (hrHPV) is a critical step in cervical carcinogenesis. We report on type-specific hrHPV persistence, clearance and incidence among screen-positive Rwandan women living with HIV (WLWH). Methods This was a nested analysis from a large cervical cancer screening study of ~ 5000 Rwandan WLWH. Women who tested positive for hrHPV and/or visual inspection with acetic acid were referred to colposcopy. For a subset of women (n = 298) who were ≥ 6 months delayed in receiving colposcopy, we tested their screening and colposcopy visit specimens using the AmpFire HPV genotyping assay that tests 14 hrHPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) individually. Results The mean, median (interquartile range [IQR]) and range of time between the screening and colposcopy visits were 644, 650 (490–820.5) and 197–1161 days, respectively. Mean, median (IQR) and range of age at the screening visit were 38, 37 (34–43) and 30–54 years, respectively. Two-hundred eighty-three (95.0%) had CD4 count (cells per mm3) data available at baseline with mean, median (IQR) and range of 592, 513 (346–717) and 0–7290, respectively. Two-hundred thirty-five WLWH were positive for at least one hrHPV type at the screening visit, of whom 50.2% had at least one HPV type-specific infection persist; 37.2% of all HPV infections detected at the screening visit persisted. Compared to all other HPV types in aggregate, HPV16 (vs. non-HPV16 types) (47.7%, p = 0.03) and HPV33 (vs. non-HPV33 types) (56.7%, p = 0.03) were significantly more likely, and HPV39 (vs. non-HPV39 types) (6.7%, p = 0.01), HPV51 (vs. non-HPV51 types) (15.6%, p < 0.01), and HPV66 (vs. non-HPV66 types (17.9%, p = 0.04) were significantly less likely, to persist. Lower CD4 counts were associated with having any persistent hrHPV infection (ptrend = 0.04) and multiple persistent hrHPV infections (ptrend = 0.04). Conclusion There is a significant proportion of WLWH with persistent hrHPV infection, emphasizing the need to vaccinate them against HPV prior to becoming sexually active.

scholarly journals High‐risk HPV positivity is a long‐term risk factor for recurrence after cervical excision procedure in women living with HIV

2021 ◽  
Author(s):  
Alberto Agarossi ◽  
Giovanni Delli Carpini ◽  
Francesco Sopracordevole ◽  
Matteo Serri ◽  
Luca Giannella ◽  
...  
Keyword(s):  
Risk Factor ◽  
High Risk ◽  
Women Living With Hiv ◽  
High Risk Hpv ◽  
Living With Hiv ◽  
Risk Factor For Recurrence

scholarly journals High-risk human papillomavirus and cervical lesions among women living with HIV/AIDS in Brazilian Amazon, Brazil

2015 ◽  
Vol 19 (6) ◽  
pp. 557-562 ◽  
Author(s):  
Leila da Silva ◽  
Angélica Miranda ◽  
Rosieny Batalha ◽  
Luiz Ferreira ◽  
Mayara Santos ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Brazilian Amazon ◽  
Cervical Lesions ◽  
Women Living With Hiv ◽  
Living With Hiv ◽  
Hiv Aids

scholarly journals Prevalence and distribution of cervical high-risk human papillomavirus and cytological abnormalities in women living with HIV in Denmark – the SHADE

BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Kristina Thorsteinsson ◽  
Merete Storgaard ◽  
Terese L. Katzenstein ◽  
Steen Ladelund ◽  
Frederikke Falkencrone Rønsholt ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Women Living With Hiv ◽  
Cytological Abnormalities ◽  
Living With Hiv

scholarly journals The Dark Side of Female HIV Patient Care: Sexual and Reproductive Health Risks in Pre- and Post-Clinical Treatments

2018 ◽  
Vol 7 (11) ◽  
pp. 402 ◽  
Author(s):  
Thu Khuat ◽  
Thu Do ◽  
Van Nguyen ◽  
Xuan Vu ◽  
Phuong Nguyen ◽  
...  
Keyword(s):  
Health Care ◽  
High Risk ◽  
Reproductive Health ◽  
Sexual And Reproductive Health ◽  
Hiv Care ◽  
High Risk Population ◽  
People Living With Hiv ◽  
Women Living With Hiv ◽  
Women And Girls ◽  
Living With Hiv

This study examines the pre- and post-clinical issues in human immunodeficiency virus (HIV) care and treatment for women and girls of high-risk population groups—namely sex workers, injecting drug users, women living with HIV, primary sexual partners of people living with HIV, adolescent girls who are children of these groups, and migrant young girls and women—in five provinces and cities in Vietnam. Through a sample of 241 surveyed participants and 48 respondents for in-depth interviews and 32 respondents in the focus group discussions, the study identifies multiple barriers that keep these groups from receiving the proper health care that is well within their human rights. Most respondents rated HIV testing as easily accessible, yet only 18.9% of the surveyed women living with HIV disclosed their infection status, while 37.8% gave no information at the most recent prenatal care visit. The level of knowledge and proper practices of sexual and reproductive health (SRH) care also remains limited. Meanwhile, modern birth control methods have yet to be widely adopted among these populations: only 30.7% of respondents reported using condoms when having sex with their husband. This increases the risks of unwanted pregnancy and abortion, as well as vulnerability to sexually transmitted infections (STIs) and HIV transmission. On the other hand, HIV-related stigma and discrimination at health care settings are still pervasive, which create significant barriers for patients to access proper care services. Based on these results, six recommendations to improve SRH status of women and girls of populations at high risk are put forward.

scholarly journals Intensification of antiretroviral treatment with raltegravir for pregnant women living with HIV at high risk of vertical transmission

2018 ◽  
Vol 4 (2) ◽  
pp. 61-65 ◽  
Author(s):  
Thanyawee Puthanakit ◽  
Nattawan Thepnarong ◽  
Surasith Chaithongwongwatthana ◽  
Suvaporn Anugulruengkitt ◽  
Orawan Anunsittichai ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Vertical Transmission ◽  
Antiretroviral Treatment ◽  
Women Living With Hiv ◽  
Living With Hiv

scholarly journals Twelve-Year Trend in the Prevalence of High-Risk Human Papillomavirus Infection Among Rwandan Women Living With HIV

2020 ◽  
Vol 222 (1) ◽  
pp. 74-81 ◽  
Author(s):  
Gad Murenzi ◽  
Faustin Kanyabwisha ◽  
Anthere Murangwa ◽  
Gallican Kubwimana ◽  
Leon Mutesa ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Hiv Care ◽  
Cd4 Counts ◽  
Women Living With Hiv ◽  
Cell Counts ◽  
Hpv Test ◽  
Living With Hiv ◽  
Cd4 Cell ◽  
Over Time

Abstract Background We examined the trend in prevalence of high-risk human papillomavirus (hrHPV) cervical infection among Rwandan women living with HIV (WLWH) over 12 years. Methods Prevalence of cervical hrHPV DNA was measured in 3 studies at 3 different time periods in 3 different groups of WLWH using 3 different but comparable hrHPV tests: a MY09/MY11 PCR test in 2005 (RWISA; n = 497), careHPV in 2009–2010 (HPV Demonstration; n = 1242), and Xpert HPV test in 2016–2018 (U54; n = 4734). Prevalences were adjusted for age and CD4 cell count. Results HrHPV prevalence decreased over time from 42.5% to 32.2% to 26.5% (P &lt; .001). CD4 cell counts improved over time (Ptrend &lt;.001) so that the percentage of WLWH with CD4 counts of ≥500 cells/μL increased from 7.7% in 2005 to 42.2% in 2009–2010 and 61.1% in 2016–2018. Thus, after adjustment for differences in CD4 counts and age, hrHPV prevalences were more similar over time: 32.6% for RWISA, 30.6% for HPV Demonstration, and 27.1% for U54 (P = .007). Conclusions Prevalence of hrHPV among WLWH has decreased over the past decade, most likely the result of improved immune reconstitution due to better HIV care and management in Rwanda.

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