Preparation of long-lasting antibacterial wound dressing through diffusion of cationic-liposome-encapsulated polyhexamethylene biguanide

2021 ◽  
pp. 105092
Author(s):  
Elnaz Ahani ◽  
Majid Montazer ◽  
Ali Mianehro ◽  
Nasrin Samadi ◽  
Tayebeh Toliyat ◽  
...  
Keyword(s):  
Wound Dressing ◽  
Cationic Liposome ◽  
Polyhexamethylene Biguanide ◽  
Through Diffusion

Evaluation of the Sorption Properties of a Self-Adhesive Hydrogel Wound Dressing

2019 ◽  
Vol 821 ◽  
pp. 10-16
Author(s):  
Javier Kristina Mutya ◽  
Nadura Riscia ◽  
Jim Clarence Rengel ◽  
Terence Tumolva
Keyword(s):  
Layer Thickness ◽  
Diffusion Coefficients ◽  
Wound Dressing ◽  
Adhesive Layer ◽  
Sorption Properties ◽  
Hydroxyethyl Cellulose ◽  
Swelling Kinetics ◽  
Hydrogel Formulation ◽  
Through Diffusion

A novel self-adhesive wound dressing product was developed using a hydroxyethyl cellulose (HEC) hydrogel layered with a TAPE-gelatin bioadhesive. This wound dressing was then evaluated for its sorption properties through diffusion and swelling tests, and the parameters analyzed were hydrogel formulation, wound dressing thickness and adhesive layer thickness. Results showed that the wound dressing produced using 6% NaOH/5% thiourea in the crosslinking solution, with 2.5 mm hydrogel thickness, and 0.2 mm TAPE-gelatin thickness had the highest water absorbed. Lastly, analysis on swelling kinetics based on a previous study was conducted to determine the diffusion coefficients for the composite wound dressing.

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