Development of bacterial cellulose incorporating silk sericin, polyhexamethylene biguanide, and glycerin with enhanced physical properties and antibacterial activities for wound dressing application

A novel bacterial cellulose (BC) composite (carboxymethylated-bacterial cellulose, CM-BC) was synthesized by Acetobacter xylinum by adding water-soluble carboxymethylated cellulose (CMC) in the culture medium. FTIR results showed that CM-BC is obtained by the incorporation of CMC in the network of BC. Water-holding capacity and water vapor transmission rates (WVTR) of CM-BC and BC are determined. The WVTR of CM-BC is comparable to that of BC, but the water-holding capacity of CM-BC is improved compared with BC. Tensile strengths measurement results showed that the fracture stress of CM-BC is higher than that of BC, indicating that CM-BC have more potential wound dressing applications than BC.

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Investigation of Nano Bacterial Cellulose Coated by Sesamum Oil for Wound Dressing Application

Procedia Materials Science ◽

10.1016/j.mspro.2015.11.109 ◽

2015 ◽

Vol 11 ◽

pp. 212-216 ◽

Cited By ~ 4

Author(s):

A. Meftahi ◽

D. Nasrolahi ◽

V. Babaeipour ◽

S. Alibakhshi ◽

S. Shahbazi

Keyword(s):

Bacterial Cellulose ◽

Wound Dressing

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A handy skin wound dressing prepared by alginate and cationic nanofibrillated cellulose derived from solid residues of herbs

BioResources ◽

10.15376/biores.16.3.5926-5946 ◽

2021 ◽

Vol 16 (3) ◽

pp. 5926-5946

Author(s):

Ting Jiang ◽

Xiaoyan Feng ◽

Rui Xu ◽

Sheng Dong ◽

Meiyan Wu ◽

...

Keyword(s):

Wound Dressing ◽

Cost Effective ◽

Nanofibrillated Cellulose ◽

Antibacterial Activities ◽

Skin Wound ◽

Natural Medicine ◽

Nanofibrous Structure ◽

New Strategy ◽

Physical Interactions ◽

Dressing Materials

Large amounts of solid residues are generated after extraction of active ingredients from herbs for the production of natural medicine, but the residues have not been well utilized. In this work, cationic nanofibrillated cellulose (CCNF) was prepared from the solid residues of Astragali Radix by etherification and homogenization. The CCNF was mixed with sodium alginate (SA) to create a hydrogel dressing by physical interactions between CCNF and SA without any addition of cross-linker. The CCNF-SA dressing exhibited moderate viscosity, good moisture-maintaining property, great antibacterial activities, good cytocompatibility, and clear acceleration of wound healing on rats. Furthermore, this CCNF-SA dressing with nanofibrous structure had moderate air permeability. Therefore, the CCNF-SA hydrogel could be used potentially as a skin wound dressing. Development of cost-effective and bioactive wound dressing materials is of crucial importance to reduce the burden on patients and healthcare systems. Also, this work provides a new strategy for valorization of the solid residues of herbs.

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A Study of the Preparation of Silk Sericin/Chitosan Composite Film for Future Wound Dressing Applications

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.804.179 ◽

2015 ◽

Vol 804 ◽

pp. 179-182 ◽

Cited By ~ 3

Author(s):

Piyapong Pankaew ◽

Pattarinee Klumdoung ◽

Kittisakchai Naemchanthara

Keyword(s):

Composite Film ◽

Wound Dressing ◽

Composite Films ◽

Fine Powder ◽

Silk Sericin ◽

Vis Spectroscopy ◽

Silk Worm ◽

Bombyx Mori Silk ◽

Film Development ◽

Chitosan Composite

Silk sericin/chitosan composite films were successfully prepared for possible future wound dressing applications. To prepare the chitosan, shrimp shells were first washed and finely ground to obtain a fine powder before extracting the chitosan using a chemical reaction method. The sericin was extracted from Thai raw cocoons of Bombyx mori silk worm via boiling and drying. To prepare the silk sericin/chitosan composite films, the silk sericin and chitosan solutions with varying volume ratios were mixed in a magnetic stirrer for 30 minutes. They were then dropped on to a plastic mold. The sample was dried at a temperature of 50 °C. The prepared composite films were characterized using UV-VIS spectroscopy, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). The results from our studies could provide a method for future composite film development.

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