scholarly journals Effects of brisk walking on autonomic nervous system reactivation in nursing home residents. Additional effects of transcutaneous vagus nerve stimulation

2016 ◽  
Vol 59 ◽  
pp. e57-e58 ◽  
Author(s):  
Jérémy Raffin ◽  
Jean-Claude Barthelemy ◽  
Philippe Terrat ◽  
Marie-Christine Diana ◽  
Emilie Achour ◽  
...  
Keyword(s):  
Nervous System ◽  
Nursing Home ◽  
Autonomic Nervous System ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Nursing Home Residents ◽  
Brisk Walking ◽  
Autonomic Nervous ◽  
Transcutaneous Vagus Nerve Stimulation

scholarly journals Brain Functional Mechanisms Determining the Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Primary Insomnia

2021 ◽  
Vol 15 ◽  
Author(s):  
Xiao Wu ◽  
Yue Zhang ◽  
Wen-ting Luo ◽  
Run-ru Mai ◽  
Xiao-yan Hou ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Vagus Nerve ◽  
Neuronal Activity ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Autonomic Nervous ◽  
Group A ◽  
Spontaneous Neuronal Activity ◽  
Group B

Transcutaneous auricular vagus nerve stimulation (taVNS) has been reported to be effective in the treatment of primary insomnia (PI); however, its efficacy varies considerably across individuals for reasons that are unclear. In order to clarify the underlying mechanisms, this study investigated the effects of taVNS on spontaneous neuronal activity and autonomic nervous system function by functional magnetic resonance imaging (fMRI) and measurement of heart rate variability (HRV), respectively, in patients with PI. Forty patients with PI were divided into effective (group A) and ineffective (group B) groups based on their response to taVNS as determined by Pittsburgh Sleep Quality Index score reduction rate (group A ≥ 25% and group B < 25%). Spontaneous neuronal activity was measured by fractional amplitude of low-frequency fluctuations (fALFF) and HRV values and was compared between the two groups as well as before vs after taVNS. We then analyzed the correlations among efficacy of taVNS for 4 weeks, the fALFF and HRV values during continuous taVNS state. The results showed that the HRV parameter values (i.e., root mean square of successive differences, percentage of adjacent NN intervals differing by >50 ms, and high frequency) of group A were higher than those of group B during continuous taVNS state. In the fMRI scan, the fALFF values of the right cerebellum, right medial superior frontal gyrus, and bilateral supplementary motor area—which belong to the sensorimotor network (SMN)—were lower in group A than in group B during continuous taVNS state. The correlation analysis revealed that the efficacy of continuous taVNS and HRV and fALFF values were interrelated. These findings demonstrate that differential regulation of the SMN by the autonomic nervous system may be responsible for inter-individual variations in the efficacy of taVNS and suggest that HRV and fALFF are potential biomarkers for predicting PI patients’ response to taVNS treatment.

scholarly journals Effects of acute transcutaneous vagus nerve stimulation on emotion recognition in adolescent depression

2019 ◽  
pp. 1-10 ◽  
Author(s):  
Julian Koenig ◽  
Peter Parzer ◽  
Niklas Haigis ◽  
Jasmin Liebemann ◽  
Tamara Jung ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Vagus Nerve ◽  
Emotion Recognition ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
System Function ◽  
Autonomic Nervous System Function ◽  
Transcutaneous Vagus Nerve Stimulation ◽  
Nervous System Function

Abstract Background Transcutaneous vagus nerve stimulation (tVNS) is a promising therapeutic option for major depressive disorder (MDD) in adults. Alternative third-line treatments for MDD in adolescents are scarce. Here we aimed to assess the effects of acute tVNS on emotion recognition in adolescents with MDD. Methods Adolescents (14–17 years) with MDD (n = 33) and non-depressed controls (n = 30) received tVNS or sham-stimulation in a cross-sectional, case–control, within-subject cross-randomized controlled trial, while performing different tasks assessing emotion recognition. Correct responses, response times, and errors of omission and commission on three different computerized emotion recognition tasks were assessed as main outcomes. Simultaneous recordings of electrocardiography and electro dermal activity, as well as sampling of saliva for the determination of α-amylase, were used to quantify the effects on autonomic nervous system function. Results tVNS had no effect on the recognition of gradually or static expressed emotions but altered response inhibition on the emotional Go/NoGo-task. Specifically, tVNS increased the likelihood of omitting a response toward sad target-stimuli in adolescents with MDD, while decreasing errors (independent of the target emotion) in controls. Effects of acute tVNS on autonomic nervous system function were found in non-depressed controls only. Conclusions Acute tVNS alters the recognition of briefly presented facial expressions of negative valence in adolescents with MDD while generally increasing emotion recognition in controls. tVNS seems to specifically alter early visual processing of stimuli of negative emotional valence in MDD. These findings suggest a potential therapeutic benefit of tVNS in adolescent MDD that requires further evaluation within clinical trials.

scholarly journals Effects of brisk walking on autonomic nervous system reactivation in nursing home residents

2018 ◽  
Vol 61 ◽  
pp. e62
Author(s):  
J. Raffin ◽  
J.C. Barthélémy ◽  
T. Busso ◽  
P. Calmels ◽  
L. Féasson ◽  
...  
Keyword(s):  
Nervous System ◽  
Nursing Home ◽  
Autonomic Nervous System ◽  
Nursing Home Residents ◽  
Brisk Walking ◽  
Autonomic Nervous

Noradrenergic interactions via autonomic nervous system: a promising target for extinction-based exposure therapy?

2013 ◽  
Vol 110 (11) ◽  
pp. 2507-2510 ◽  
Author(s):  
Gürsel Çalışkan ◽  
Anne Albrecht
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Biol Psychiatry ◽  
Extinction Learning ◽  
System A ◽  
Promising Target ◽  
Repetitive Exposure

Fearful associations can be replaced by neutral associations through repetitive exposure of an individual to the fearful situation without the aversive component. Recently, Peña and colleagues (Peña DF, Engineer ND, McIntyre CK. Biol Psychiatry 73: 1071–1077, 2013) demonstrated that pairing activation of noradrenergic (NA) pathways through vagus nerve stimulation (VNS) with extinction learning accelerates consolidation of extinction memories in rats. Their findings stress the importance of activating the NA system through VNS in treatment of anxiety disorders such as PTSD or phobia.

Effect of Transcutaneous Vagus Nerve Stimulation in Dysphagia After Lateral Medullary Infarction: A Case Report

2019 ◽  
Vol 28 (4) ◽  
pp. 1381-1387
Author(s):  
Ying Yuan ◽  
Jie Wang ◽  
Dongyu Wu ◽  
Dahua Zhang ◽  
Weiqun Song
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Rating Scale ◽  
Tube Feeding ◽  
Nasogastric Feeding ◽  
Lateral Medullary Infarction ◽  
Severe Dysphagia ◽  
Transcutaneous Vagus Nerve Stimulation ◽  
Medullary Infarction

Purpose Severe dysphagia with weak pharyngeal peristalsis after dorsal lateral medullary infarction (LMI) requires long-term tube feeding. However, no study is currently available on therapeutic effectiveness in severe dysphagia caused by nuclear damage of vagus nerve after dorsal LMI. The purpose of the present investigation was to explore the potential of transcutaneous vagus nerve stimulation (tVNS) to improve severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Method We assessed the efficacy of 6-week tVNS in a 28-year-old woman presented with persisting severe dysphagia after dorsal LMI who had been on nasogastric feeding for 6 months. tVNS was applied for 20 min twice a day, 5 days a week, for 6 weeks. The outcome measures included saliva spitted, Swallow Function Scoring System, Functional Oral Intake Scale, Clinical Assessment of Dysphagia With Wallenberg Syndrome, Yale Pharyngeal Residue Severity Rating Scale, and upper esophagus X-ray examination. Results After tVNS, the patient was advanced to a full oral diet without head rotation or spitting. No saliva residue was found in the valleculae and pyriform sinuses. Contrast medium freely passed through the upper esophageal sphincter. Conclusion Our findings suggest that tVNS might provide a useful means for recovery of severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Supplemental Material https://doi.org/10.23641/asha.9755438

scholarly journals Transcutaneous Vagus Nerve Stimulation is Associated with Lower Mechanical Ventilation and Mortality in COVID-19 Patients

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Nemechek P ◽  
Antonelli G ◽  
Braida A
Keyword(s):  
Mechanical Ventilation ◽  
Respiratory Failure ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Safety And Efficacy ◽  
Transcutaneous Vagus Nerve Stimulation

Objective: Evaluate the safety and efficacy of transcutaneous vagus nerve stimulation in preventing respiratory failure and improving survival in hospitalized COVID-19 patients.

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