scholarly journals Probe-based confocal laser endomicroscopy of the respiratory tract: A data consistency analysis

2013 ◽  
Vol 107 (8) ◽  
pp. 1234-1240 ◽  
Author(s):  
J. Yserbyt ◽  
C. Dooms ◽  
M. Decramer ◽  
G.M. Verleden
2021 ◽  
Vol 3 (2) ◽  
pp. 20-25
Author(s):  
Anna G. Sotnikova ◽  
Alexander V. Averyanov ◽  
Tamara A. Turusina ◽  
Victor N. Lesnyak ◽  
Dmitry V. Sazonov ◽  
...  

The case of a rare lung disease - alveolar proteinosis diagnosed with advanced technologies, including confocal laser endomicroscopy of respiratory tract (alveoscopy) is presented. After confirming the diagnosis the patient undewent high volume bronchoalveolar lavage of both lungs with positive clinical and radiologic dynamics.


2011 ◽  
Vol 2 (4) ◽  
pp. 5-12
Author(s):  
Alexander V. Averyanov ◽  
Olesya V. Danilevskaya ◽  
Dmitry V. Sazonov ◽  
Oleg P. Kuzovlev ◽  
Fedor G. Zabozlaev ◽  
...  

We have described the principle and method of confocal laser endomicroscopy using the system Cellvizio lung probe Alveoflex (Mauna Kea Technologies, France) to study the distal lower respiratory tract in real time. Acynoscopy has been performed in 25 patients aged from 24 to 75 years with different lung pathology. The problems associated with using of this technology and its potential practical applications are discussed.


Thorax ◽  
2017 ◽  
Vol 73 (2) ◽  
pp. 188-190 ◽  
Author(s):  
J Yserbyt ◽  
C Dooms ◽  
W Janssens ◽  
G M Verleden

Probe-based confocal laser endomicroscopy (pCLE) was performed in 15 patients with emphysema and 15 healthy subjects to visualise small airways in a direct and dynamic way. Morphometry shows that the median cross-sectional area of the alveolar openings at the level of the alveolar ducts is significantly larger in emphysema (7.2×104 µm2) as compared with healthy subjects (5.2×104 µm2) (p=0.0002). Normalised autofluorescence intensity histograms show a decrease in median autofluorescence intensity (mAFI) in emphysema (p=0.001). mAFI correlates well with Tiffeneau index (r=0.66, p=0.007, 95% CI 0.21 to 0.88). Autofluorescence intensity in emphysema correlates with corresponding data of CT-based quantification. pCLE-based morphometry and autofluorescence intensity analysis in emphysema is able to detect regional changes inside the ‘quiet zone’.Trial registration numberResults, NCT01204970.


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