Biobased green method to synthesise palladium and iron nanoparticles using Terminalia chebula aqueous extract

Author(s):  
Kesarla Mohan Kumar ◽  
Badal Kumar Mandal ◽  
Koppala Siva Kumar ◽  
Pamanji Sreedhara Reddy ◽  
Bojja Sreedhar
Phytomedicine ◽  
2004 ◽  
Vol 11 (6) ◽  
pp. 530-538 ◽  
Author(s):  
G.H. Naik ◽  
K.I. Priyadarsini ◽  
D.B. Naik ◽  
R. Gangabhagirathi ◽  
H. Mohan

2012 ◽  
Vol 38 (2) ◽  
pp. 204-214 ◽  
Author(s):  
S. Tayal ◽  
S. Duggal ◽  
P. Bandyopadhyay ◽  
A. Aggarwal ◽  
S. Tandon ◽  
...  

2021 ◽  
pp. 75-79
Author(s):  
Asha D. V. Bensy ◽  
G. Johnsi Christobel

Marine macroalgae produce numerous bioactive compounds with potential pharmacological properties. In this study, macroalga was collected from the Gulf of Mannar, India and identified as, Turbinaria conoides (J. Agardh). The aqueous extract of T. conoides was used to synthesize iron nanoparticles (NPs). The synthesized iron NPs were characterized by X –ray diffraction analysis, Scanning Electron Microscopy, and Transmission Electron Microscopy. The synthesized NPs showed potent activity against DLD1 and HeLa cell lines.


2014 ◽  
Vol 15 (3) ◽  
pp. 278-282 ◽  
Author(s):  
Sushma S Nayak ◽  
Sharda C Metgud ◽  
Uday Kumar Bolmal

ABSTRACT Aim Many weapons are available in the arsenal of a dental professional to combat dental caries, which is almost ubiquitously present. From a public health perspective, most of these weapons are far from being an ideal drug. Hence, there is a demand for better and effective antibacterial agents. This factor stimulated the process of the present study. The aim of the study was to determine the effect of ethanol extract of Terminalia chebula on Streptococcus mutans. Materials and methods Dried ripe fruits of Terminalia chebula were procured and powdered. Physical tests were done to estimate purity of the fruit powder. Hydroethanolic and aqueous extracts were prepared according to standard procedures. Minimum inhibitory concentration of the extracts was determined by tube dilution method and confirmed by agar dilution method. The effect of the hydroethanolic extract on sucrose induced adhesion, glucan-induced aggregation and on glycolysis of Streptococcus mutans was also assessed. Preservative, gelling agent and sweetener were added in suitable quantities to the ethanol extract, and mouthrinse was formulated. Minimum inhibitory concentration of the formulation was also determined. Results Yield was better in case of aqueous extract. The Minimum inhibitory concentration of hydroethanolic extract was determined to be 2.5%. Minimum inhibitory concentration of the aqueous extract was determined to be 10%. Hydroethanolic extract of Terminalia chebula (2.5%) inhibited sucrose induced adherence and aggregation of Streptococcus mutans in vitro. Conclusion The mouthrinse formulated from ethanol extract of Terminalia chebula demonstrated substantial antibacterial activity and could be used as an effective anticaries agent. Clinical Significance Terminalia chebula mouthrinse can be effectively used in clinical practice as an anticaries mouthrinse with additional benefit being that it is safe and economical. How to cite this article Nayak SS, Ankola AV, Metgud SC, Bolmal UK. An in vitro Study to determine the Effect of Terminalia chebula Extract and Its Formulation on Streptococcus mutans. J Contemp Dent Pract 2014;15(3):278-282.


2012 ◽  
Vol 1 (8) ◽  
pp. 217-220 ◽  
Author(s):  
BE Ravi Shankara ◽  
YL Ramachandra ◽  
S Sundara Rajan ◽  
J Preetham ◽  
PS Sujan Ganapathy

The leaf galls of Terminalia chebula is used widely as Karkatasringi in south Indian markets. Karkatashringi is an important crude drug employed in various indigenous systems of medicine against several diseases and the drug has diverse medicinal properties. The present study was carried out to understand the antimicrobial activity of various extracts. The antibacterial activity of T. chebula (leaf gall) was evaluated against ten bacterial strains including Gram-positive and Gram-negative bacteria using the agar-well diffusion method. Among the two extracts tested, the ethanol extract presented the best results against all the bacteria while aqueous extract showed moderate inhibition of the microbial growth. Each extract is unique against different microorganisms; Staphylococcus aureus was more susceptible to both extract among the tested organisms, whereas Serratia marcescens and Proteus mirabilis were less susceptible for ethanol and aqueous extract respectively. The inhibitory effect of the extracts was compared with standard antibiotic Ciprofloxacin.DOI: http://dx.doi.org/10.3329/icpj.v1i8.11254 International Current Pharmaceutical Journal 2012, 1(8): 217-220 


Author(s):  
Yadong Zhou ◽  
Fafu Dou ◽  
Tahani Awad Alahmadi ◽  
Sulaiman Ali Alharbi ◽  
Milton Wainwright

IntroductionThe preparation and formulation of new chemotherapeutic supplements and drugs with remarkable effects for the treatment of cancer are in the priority of both developing and developed countries. Recently, iron nanoparticles have been used as modern chemotherapeutic drugs for the treatment of several cancers such as leukemia, lung cancer, breast cancer, prostate cancer, etc. In the present study, iron nanoparticles were green-synthesized using the aqueous extract of Alhagi sparsifolia leaf aqueous extract.Material and methodsThe synthesized FeNPs were characterized by analytical techniques including SEM, TEM, UV-Vis., and FT-IR. The anti-human colorectal carcinoma activity of FeNPs was evaluated using MTT assay. In the cellular and molecular part of the recent study, the treated cells with FeNPs were assessed by MTT assay for 48h about the cytotoxicity and anti-human colorectal carcinoma properties on normal (HUVEC) and colorectal carcinoma cell lines i.e. HT-29, HCT 116, HCT-8, and Ramos.2G6.4C10.ResultsThe nanoparticles were formed in a spherical shape in the average size of 47.24 nm. In the antioxidant test, the IC50 of FeNPs and BHT against DPPH free radicals were 161 and 134 µg/mL, respectively. The viability of malignant colorectal cell line reduced dose-dependently in the presence of FeNPs. The IC50 of FeNPs were 250, 293, 276, and 344 µg/mL against HT-29, HCT 116, HCT-8, and Ramos.2G6.4C10 cell lines, respectively.ConclusionsAfter clinical study, iron nanoparticles containing Alhagi sparsifolia leaf aqueous extract may be used to formulate a new chemotherapeutic drug or supplement to treat the several types of human colorectal carcinoma.


2007 ◽  
Vol 18 (4) ◽  
pp. 152 ◽  
Author(s):  
A Velmurugan ◽  
Usha Carounanidy ◽  
R Satyanarayanan

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