A water-soluble molecular probe with aggregation-induced emission for discriminative detection of Al3+ and Pb2+ and imaging in seedling root of Arabidopsis

A new water-soluble ligand bearing a tetrasulfonated calix[4]arene was constructed for ratiometric detection of Al3+ based on an aggregation-induced fluorescence enhancement mechanism.

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SYNTHESIS AND PROPERTY OF A WATER-SOLUBLE AGGREGATION-INDUCED EMISSION ENHANCEMENT CONJUGATED POLYMER

Acta Polymerica Sinica ◽

10.3724/sp.j.1105.2012.11322 ◽

2012 ◽

Vol 012 (4) ◽

pp. 453-461 ◽

Cited By ~ 7

Author(s):

Yanmei WU ◽

Jianbing SHI ◽

Bin TONG ◽

Junge ZHI ◽

Yuping DONG

Keyword(s):

Conjugated Polymer ◽

Water Soluble ◽

Aggregation Induced Emission ◽

Emission Enhancement

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A water-soluble two-dimensional supramolecular organic framework with aggregation-induced emission for DNA affinity and live-cell imaging

Journal of Materials Chemistry B ◽

10.1039/c8tb03206h ◽

2019 ◽

Vol 7 (9) ◽

pp. 1435-1441 ◽

Cited By ~ 13

Author(s):

Hui Liu ◽

Zhaohui Zhang ◽

Yingjie Zhao ◽

Yongxin Zhou ◽

Bo Xue ◽

...

Keyword(s):

Live Cell Imaging ◽

Cell Imaging ◽

Live Cell ◽

Water Soluble ◽

Two Dimensional ◽

Aggregation Induced Emission ◽

Organic Framework

A water-soluble two-dimensional supramolecular organic framework (2D SOF) with AIE effect was prepared and exhibited excellent live-cell imaging behavior.

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Sensitive Water-Soluble Fluorescent Probe Based on Umpolung and Aggregation-Induced Emission Strategies for Selective Detection of Hg2+ in Living Cells and Zebrafish

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.8b06895 ◽

2019 ◽

Vol 67 (8) ◽

pp. 2377-2383 ◽

Cited By ~ 16

Author(s):

Tang Gao ◽

Xueyan Huang ◽

Shuai Huang ◽

Jie Dong ◽

Kai Yuan ◽

...

Keyword(s):

Fluorescent Probe ◽

Living Cells ◽

Water Soluble ◽

Selective Detection ◽

Aggregation Induced Emission

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Aggregation-Induced Emission of Water-Soluble Tetraphenylethene Derivatives at Polarized Liquid|Liquid Interfaces

Langmuir ◽

10.1021/acs.langmuir.0c01962 ◽

2020 ◽

Vol 36 (35) ◽

pp. 10597-10605

Author(s):

Makoto Nabara ◽

Sho Yamamoto ◽

Yoshio Nishiyama ◽

Hirohisa Nagatani

Keyword(s):

Water Soluble ◽

Liquid Interfaces ◽

Aggregation Induced Emission

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Fast Broad-Spectrum Staining and Photodynamic Inhibition of Pathogenic Microorganisms by a Water-Soluble Aggregation-Induced Emission Photosensitizer

Frontiers in Chemistry ◽

10.3389/fchem.2021.755419 ◽

2021 ◽

Vol 9 ◽

Author(s):

Qi Zhou ◽

Xiaoming Lyu ◽

Bing Cao ◽

Xueping Liu ◽

Jing Liu ◽

...

Keyword(s):

Fluorescent Imaging ◽

Water Soluble ◽

Pathogenic Microorganisms ◽

Photodynamic Treatment ◽

Aggregation Induced Emission ◽

E Coli ◽

Imaging Detection ◽

Positively Charged

Pathogenic microorganisms pose great challenges to public health, which is constantly urgent to develop extra strategies for the fast staining and efficient treatments. In addition, once bacteria form stubborn biofilm, extracellular polymeric substance (EPS) within biofilm can act as protective barriers to prevent external damage and inward diffusion of traditional antibiotics, which makes it frequently develop drug-resistant ones and even hard to treat. Therefore, it is imperative to develop more efficient methods for the imaging/detection and efficient inhibition of pathogenic microorganisms. Here, a water-soluble aggregation-induced emission (AIE)-active photosensitizer TPA-PyOH was employed for fast imaging and photodynamic treatment of several typical pathogens, such as S. aureus, methicillin-resistant Staphylococcus aureus, L. monocytogenes, C. albicans, and E. coli. TPA-PyOH was non-fluorescent in water, upon incubation with pathogen, positively charged TPA-PyOH rapidly adhered to pathogenic membrane, thus the molecular motion of TPA-PyOH was restricted to exhibit AIE-active fluorescence for turn-on imaging with minimal background. Upon further white light irradiation, efficient reactive oxygen species (ROS) was in-situ generated to damage the membrane and inhibit the pathogen eventually. Furthermore, S. aureus biofilm could be suppressed in vitro. Thus, water-soluble TPA-PyOH was a potent AIE-active photosensitizer for fast fluorescent imaging with minimal background and photodynamic inhibition of pathogenic microorganisms.

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