HPLC-DAD phytochemical profiles of Thymus cariensis and T. cilicicus with antioxidant, cytotoxic, anticholinesterase, anti-urease, anti-tyrosinase, and antidiabetic activities

Abstract Phytochemical profiles of essential oil (EO), fatty acids, and n-hexane (CAH), diethyl ether (CAD), ethyl acetate (CAE) and methanol extracts (CAM) of Cota altissima L. J. Gay (syn. Anthemis altissima L.) were investigated as well as their antioxidant, anti-inflammatory, antidiabetic and antimicrobial activites. The essential oil was characterized by the content of acetophenone (35.8%) and β-caryophyllene (10.3%) by GC-MS/FID. Linoleic and oleic acid were found as main fatty acids. The major constituents of the extracts were found to be 5-caffeoylquinic acid, 3,5-dicaffeoylquinic acid, isorhamnetin glucoside, quercetin and quercetin glucoside by LC-MS/MS. Antioxidant activities of the extracts were determined by scavenging of DPPH and ABTS free radicals. Also, the inhibitory effects on lipoxygenase and α-glucosidase enzymes were determined. Antimicrobial activity was evaluated against Gram positive, Gram negative bacteria and yeast pathogens. CAM showed the highest antioxidant activity against DPPH and ABTS radicals with IC50 values of 126.60 and 144.40 μg/mL, respectively. In the anti-inflammatory activity, CAE demonstrated the highest antilipoxygenase activity with an IC50 value of 105.40 μg/mL, whereas, CAD showed the best inhibition of α-glucosidase with an IC50 value of 396.40 μg/mL in the antidiabetic activity. CAH was effective against Staphylococcus aureus at MIC = 312.5 µg/mL. This is the first report on antidiabetic, anti-inflammatory and antimicrobial activities of different extracts of C. altissima.

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The Brown Seaweeds of Scotland, Their Importance and Applications

Environments ◽

10.3390/environments8060059 ◽

2021 ◽

Vol 8 (6) ◽

pp. 59

Author(s):

Omar Al-Dulaimi ◽

Mostafa E. Rateb ◽

Andrew S. Hursthouse ◽

Gary Thomson ◽

Mohammed Yaseen

Keyword(s):

Waste Treatment ◽

Biological Activities ◽

Chemical Diversity ◽

Great Opportunity ◽

Brown Seaweeds ◽

Extraction And Separation ◽

The Status ◽

Potential Applications ◽

The Uk ◽

Phytochemical Profiles

More than 50% of the UK coastline is situated in Scotland under legislative jurisdiction; therefore, there is a great opportunity for regionally focused economic development by the rational use of sustainable marine bio-sources. We review the importance of seaweeds in general, and more specifically, wrack brown seaweeds which are washed from the sea and accumulated in the wrack zone and their economic impact. Rules and regulations governing the harvesting of seaweed, potential sites for harvesting, along with the status of industrial application are discussed. We describe extraction and separation methods of natural products from these seaweeds along with their phytochemical profiles. Many potential applications for these derivatives exist in agriculture, energy, nutrition, biomaterials, waste treatment (composting), pharmaceuticals, cosmetics and other applications. The chemical diversity of the natural compounds present in these seaweeds is an opportunity to further investigate a range of chemical scaffolds, evaluate their biological activities, and develop them for better pharmaceutical or biotechnological applications. The key message is the significant opportunity for the development of high value products from a seaweed processing industry in Scotland, based on a sustainable resource, and locally regulated.

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Influence of Moderate to High Salinity on the Phytochemical Profiles of Two Salinity-Tolerant Spinach Genotypes

ACS Food Science & Technology ◽

10.1021/acsfoodscitech.0c00034 ◽

2021 ◽

Author(s):

Fakir Shahidullah Tareq ◽

Raghavendhar R. Kotha ◽

Jorge F. S. Ferreira ◽

Devinder Sandhu ◽

Devanand L. Luthria

Keyword(s):

High Salinity ◽

Phytochemical Profiles

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Wild pink bayberry fruit: the effect of in vitro gastrointestinal digestion on phytochemical profiles, and antioxidant and antiproliferative activities

Food & Function ◽

10.1039/d0fo02370a ◽

2021 ◽

Author(s):

Wen Xia ◽

Yanyun Lin ◽

Ersheng Gong ◽

Tong Li ◽

Fengli Lian ◽

...

Keyword(s):

Dietary Supplement ◽

Antiproliferative Activity ◽

Gastrointestinal Digestion ◽

In Vitro Gastrointestinal Digestion ◽

Phytochemical Profiles ◽

Antiproliferative Activities

In general, pink bayberry cultivar, a vital source of polyphenols, showed strong antiproliferative activity after digestion at the end of the intestinal and colon steps, which can be considered as a dietary supplement.

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Comparative assessment of phytochemical profiles and antioxidant properties of Tunisian and Egyptian anise (Pimpinella anisum L.) seeds

Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology ◽

10.1080/11263504.2017.1403394 ◽

2017 ◽

Vol 152 (5) ◽

pp. 971-978 ◽

Cited By ~ 11

Author(s):

I. Bettaieb Rebey ◽

S. Bourgou ◽

W. Aidi Wannes ◽

I. Hamrouni Selami ◽

M. Saidani Tounsi ◽

...

Keyword(s):

Antioxidant Properties ◽

Comparative Assessment ◽

Pimpinella Anisum ◽

Phytochemical Profiles

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A Review on Cistus sp.: Phytochemical and Antimicrobial Activities

Plants ◽

10.3390/plants10061214 ◽

2021 ◽

Vol 10 (6) ◽

pp. 1214

Author(s):

Imane Zalegh ◽

Mohamed Akssira ◽

Mohammed Bourhia ◽

Fouad Mellouki ◽

Naima Rhallabi ◽

...

Keyword(s):

Infectious Diseases ◽

Essential Oils ◽

Mediterranean Sea ◽

Scientific Literature ◽

Antimicrobial Activities ◽

Mechanisms Of Action ◽

Pharmacological Activities ◽

Global View ◽

Chemical Profiles ◽

Phytochemical Profiles

Resistance to drugs is reaching alarming levels and is placing human health at risk. With the lack of new antimicrobials drugs, infectious diseases are becoming harder to treat. Hence, there is an increasing awareness of active phytochemicals with therapeutic functions. The tremendous research interest on the Cistus L. genus includes numerous plants used in traditional medicine by people living around the Mediterranean Sea, also resulted in some interesting discoveries and written literature. This review aimed at gathering scientific literature about Cistus species, describing phytochemical profiles and the various pharmacological activities. We also extensively reviewed the antimicrobial activities, including antiviral, antiparasitic, antifungal, and antibacterial potentials of Essential Oils (EO), raw extracts as well as isolated compounds. Mechanisms of action along with methods used are also investigated in this review. Considering the findings of the Cistus species extracts, this genus offers an adequate reserve of active phytochemicals since many have been used to create drugs. Therefore, this review work can serve society by providing a global view on Cistus L. sp. regarding pharmacological potentials and their chemical profiles.

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