Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

BackgroundEarly detection programmes aim to reduce the duration of untreated psychosis (DUP) by public education and by prompt access to treatment via active outreach detection teams.AimsTo determine whether those with first-episode psychosis in an early detection healthcare area with existing referral channels differ from those who access care via detection teams.MethodThose with first-episode psychosis recruited via detection teams were compared with those accessing treatment via conventional channels, at baseline and after 3 months of acute treatment.ResultsPatients recruited via detection teams are younger males with a longer DUP a less dramatic symptom picture and better functioning; however they recover more slowly, and have more symptoms at 3-month follow-up.ConclusionsAfter establishing low threshold active case-seeking detection teams, we found clear differences between those patients entering treatment via detection teams v. those obtaining treatment via the usual channels. Such profiling may be informative for early detection service development.

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Victims and Perpetrators of Child Sexual Abuse: Abusive Contact and Penetration Experiences

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18189593 ◽

2021 ◽

Vol 18 (18) ◽

pp. 9593

Author(s):

Marta Ferragut ◽

Margarita Ortiz-Tallo ◽

Maria J. Blanca

Keyword(s):

Gender Differences ◽

Sexual Abuse ◽

Child Sexual Abuse ◽

Early Detection ◽

Physical Contact ◽

First Episode ◽

Future Research ◽

Male Victims ◽

Research And Practice ◽

Female Perpetrator

Child sexual abuse (CSA) includes abusive contact experiences, which habitually impact the victim’s whole life. This study aims to analyze the characteristics of six CSA experiences with physical contact, including penetration, in a representative sample of the Spanish population. Participants were 1071 Spanish adults (53% males; Mage: 45.37) who completed the Child Sexual Abuse Experiences Questionnaire. The victim’s age at the first episode, the perpetrator’s characteristics, and the number of times that each experience occurred were analyzed, taking into account gender differences. Results were reported for every experience independently. The most prevalent age at the first experience was from 6 years old onwards, but with differences in some experiences. The abuses usually happened more than once, committed by the same person. The most prevalent perpetrator is a male, although a female perpetrator is more prevalent in male victims. Most of the abuses were committed by an adult acquaintance, a strange adult, and other minors, with some gender differences. The implications of the results concerning every CSA experience are discussed, highlighting their value for future research and practice, the design of preventive programs, and early detection of CSA.

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Prediction and Early Detection of First-Episode Psychosis

Handbook of Schizophrenia Spectrum Disorders, Volume II ◽

10.1007/978-94-007-0831-0_9 ◽

2011 ◽

pp. 207-267 ◽

Cited By ~ 3

Author(s):

Frauke Schultze-Lutter ◽

Chantal Michel ◽

Stephan Ruhrmann ◽

Joachim Klosterkötter ◽

Benno G. Schimmelmann

Keyword(s):

Early Detection ◽

First Episode Psychosis ◽

First Episode ◽

Episode Psychosis

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Symptomatic Remission and Cognitive Impairment in First-Episode Schizophrenia

The Journal of Clinical Psychiatry ◽

10.4088/jcp.13m08355 ◽

2013 ◽

Vol 74 (11) ◽

pp. e1046-e1053 ◽

Cited By ~ 20

Author(s):

Wing Chung Chang ◽

Christy Lai Ming Hui ◽

Gloria Hoi Yan Wong ◽

Sherry Kit Wa Chan ◽

Edwin Ho Ming Lee ◽

...

Keyword(s):

Cognitive Impairment ◽

First Episode ◽

Symptomatic Remission ◽

First Episode Schizophrenia

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FC5E THE IMPACT OF AN EARLY DETECTION TEAM (LEO CAT) AND GP EDUCATION IN FIRST EPISODE PSYCHOSIS

Schizophrenia Research ◽

10.1016/s0920-9964(06)70122-0 ◽

2006 ◽

Vol 86 ◽

pp. S41 ◽

Cited By ~ 2

Author(s):

P. Power ◽

N. Reynolds ◽

H. Fisher ◽

E. Iacoponi ◽

P. Garety ◽

...

Keyword(s):

Early Detection ◽

First Episode Psychosis ◽

First Episode ◽

Episode Psychosis ◽

The Impact

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History of offending behavior in first episode psychosis patients: A marker of specific clinical needs and a call for early detection strategies among young offenders

Schizophrenia Research ◽

10.1016/j.schres.2014.09.078 ◽

2015 ◽

Vol 161 (2-3) ◽

pp. 163-168 ◽

Cited By ~ 14

Author(s):

Régis Marion-Veyron ◽

Martin Lambert ◽

Sue M. Cotton ◽

Benno G. Schimmelmann ◽

Bruno Gravier ◽

...

Keyword(s):

Early Detection ◽

First Episode Psychosis ◽

First Episode ◽

Young Offenders ◽

Offending Behavior ◽

Episode Psychosis ◽

History Of ◽

Detection Strategies

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Early symptom progression rate is related to ALS outcome: A prospective population-based study

Neurology ◽

10.1212/wnl.59.12.2012-a ◽

2002 ◽

Vol 59 (12) ◽

pp. 2012-2013 ◽

Cited By ~ 6

Author(s):

M. Turner ◽

A. Al-Chalabi ◽

A. Chio ◽

G. Mora

Keyword(s):

Population Based ◽

Progression Rate ◽

Population Based Study ◽

Early Symptom ◽

Symptom Progression

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Psychosocial functioning in relation to symptomatic remission: A longitudinal study of first episode schizophrenia

European Psychiatry ◽

10.1016/j.eurpsy.2015.08.001 ◽

2015 ◽

Vol 30 (8) ◽

pp. 907-913 ◽

Cited By ~ 15

Author(s):

K. Jaracz ◽

K. Górna ◽

J. Kiejda ◽

B. Grabowska-Fudala ◽

J. Jaracz ◽

...

Keyword(s):

Social Functioning ◽

Psychosocial Functioning ◽

Early Stage ◽

First Episode ◽

Term Outcome ◽

Long Term Outcome ◽

Poor Outcome ◽

Remission Status ◽

Symptomatic Remission

AbstractObjectivesThe aims of the study were: (1) to evaluate longitudinally symptomatic remission in first-episode (FE) schizophrenia, (2) to describe symptoms, social functioning and quality of life (Qol) in relation to remission status, and (3) to determine the long-term outcome of schizophrenia and its early predictors.MethodsSixty-four patients were assessed 1 month after a first hospitalization (T1), 12 months (T2), 4–6 years (T3), and 7–11 years (T4) after T1. The patients were allocated to three remission groups according to their remission status over the whole observation period, e.g. stable remission (SR), unstable remission (UR) and non-remission (NR). The PANSS, Social Functioning Scale and WHOQoL were used to evaluate the patients’ psychosocial functioning levels, symptomatic and functional remissions and satisfying QoL. A good outcome was defined as meeting, simultaneously, the criteria of symptomatic and functional remissions and satisfying QoL at T4, while failure to meet all of these criteria was defined as a poor outcome.ResultsAmong them, 17.2% patients were in stable remission, 57.8% in unstable remission and 25.0% were unremitted at all time points. The SR group had lower levels of psychopathological symptoms and reported better social functioning and QoL than the NR group. During the follow-up, the symptoms increased, social functioning slightly improved and QoL did not change. At T4, 53% of the sample had a poor outcome, which was independently predicted by the longer duration of untreated psychosis and a lack of satisfying QoL at T1.ConclusionsOur results demonstrate that: (1) the long-term course in schizophrenia is heterogeneous and that three illness trajectories exist, (2) social functioning and QoL are only partially connected with symptomatic remission (3), the risk of a poor outcome may potentially be reduced by appropriate interventions at an early stage of the illness.

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Initiatives to shorten duration of untreated psychosis: systematic review

The British Journal of Psychiatry ◽

10.1192/bjp.bp.109.075622 ◽

2011 ◽

Vol 198 (4) ◽

pp. 256-263 ◽

Cited By ~ 94

Author(s):

Brynmor Lloyd-Evans ◽

Michelle Crosby ◽

Sarah Stockton ◽

Stephen Pilling ◽

Lorna Hobbs ◽

...

Keyword(s):

Systematic Review ◽

Early Detection ◽

Public Awareness ◽

National Level ◽

First Episode ◽

Duration Of Untreated Psychosis ◽

Early Intervention Services ◽

Awareness Campaigns ◽

Poor Outcomes ◽

Practitioner Education

BackgroundLong duration of untreated psychosis (DUP) is common and associated with poor outcomes. Strategies to enhance early detection of first-episode psychosis have been advocated.AimsTo evaluate initiatives for early detection of psychosis.MethodSystematic review of available evidence on the effectiveness of early detection initiatives to reduce the DUP.ResultsThe review included 11 studies which evaluated 8 early detection initiatives. Evidence suggests that general practitioner education campaigns and dedicated early intervention services do not by themselves reduce DUP or generate more treated cases. Evidence for multifocus initiatives is mixed: intensive campaigns targeting the general public as well as relevant professionals may be needed. No studies evaluated initiatives targeting young people or professionals from non-health organisations.ConclusionsHow early detection can be achieved is not clear. Evidence is most promising for intensive public awareness campaigns: these require organisation and resourcing at a regional or national level. More good-quality studies are needed to address gaps in knowledge.

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