Associations between weekly air pollution exposure and congenital heart disease

2021 ◽  
Vol 757 ◽  
pp. 143821
Author(s):  
Qi Zhang ◽  
Shu Sun ◽  
Xinmiao Sui ◽  
Liu Ding ◽  
Mei Yang ◽  
...  
Keyword(s):  
Air Pollution ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Preexisting coronary heart disease and susceptibility to long-term effects of traffic-related air pollution: A matched cohort analysis

2020 ◽  
pp. 204748732092198 ◽  
Author(s):  
Gali Cohen ◽  
David M Steinberg ◽  
Lital Keinan-Boker ◽  
Yuval ◽  
Ilan Levy ◽  
...  
Keyword(s):  
Air Pollution ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Nitrogen Oxides ◽  
Hazard Ratio ◽  
Matched Cohort ◽  
Air Pollution Exposure ◽  
All Cause Mortality ◽  
Pollution Exposure ◽  
Age And Sex

Background Individuals with coronary heart disease are considered susceptible to traffic-related air pollution exposure. Yet, cohort-based evidence on whether preexisting coronary heart disease modifies the association of traffic-related air pollution with health outcomes is lacking. Aim Using data of four Israeli cohorts, we compared associations of traffic-related air pollution with mortality and cancer between coronary heart disease patients and matched controls from the general population. Methods Subjects hospitalized with acute coronary syndrome from two patient cohorts (inception years: 1992–1993 and 2006–2014) were age- and sex-matched to coronary heart disease-free participants of two cycles of the Israeli National Health and Nutrition Surveys (inception years: 1999–2001 and 2005–2006). Ambient concentrations of nitrogen oxides at the residential place served as a proxy for traffic-related air pollution exposure across all cohorts, based on a high-resolution national land use regression model (50 m). Data on all-cause mortality (last update: 2018) and cancer incidence (last update: 2016) were retrieved from national registries. Cox-derived stratum-specific hazard ratios with 95% confidence intervals were calculated, adjusted for harmonized covariates across cohorts, including age, sex, ethnicity, neighborhood socioeconomic status, smoking, diabetes, hypertension, prior stroke and prior malignancy (the latter only in the mortality analysis). Effect-modification was examined by testing nitrogen oxides-by-coronary heart disease interaction term in the entire matched cohort. Results The cohort (mean (standard deviation) age 61.5 (14) years; 44% women) included 2393 matched pairs, among them 2040 were cancer-free at baseline. During a median (25th–75th percentiles) follow-up of 13 (10–19) and 11 (7–17) years, 1458 deaths and 536 new cancer cases were identified, respectively. In multivariable-adjusted models, a 10-parts per billion nitrogen oxides increment was positively associated with all-cause mortality among coronary heart disease patients (hazard ratio = 1.13, 95% confidence interval 1.05–1.22), but not among controls (hazard ratio = 1.00, 0.93–1.08) ( pinteraction = 0.003). A similar pattern was seen for all-cancer incidence (hazard ratioCHD = 1.19 (1.03–1.37), hazard ratioCHD-Free = 0.93 (0.84–1.04) ( pinteraction = 0.01)). Associations were robust to multiple sensitivity analyses. Conclusions Coronary heart disease patients might be at increased risk for traffic-related air pollution-associated mortality and cancer, irrespective of their age and sex. Patients and clinicians should be more aware of the adverse health effects on coronary heart disease patients of chronic exposure to vehicle emissions.

051 Reducing particulate air pollution exposure in patients with coronary heart disease: improved cardiovascular health

Heart ◽  
2010 ◽  
Vol 96 (Suppl 1) ◽  
pp. A30-A31
Author(s):  
J P Langrish ◽  
X Li ◽  
S Wang ◽  
M M Y Lee ◽  
G D Barnes ◽  
...  
Keyword(s):  
Air Pollution ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Health ◽  
Particulate Air Pollution ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Maternal air pollution exposure associated with risk of congenital heart defect in pre-pregnancy overweighted women

2020 ◽  
Vol 712 ◽  
pp. 136470 ◽  
Author(s):  
Yin Yang ◽  
Qingmei Lin ◽  
Yin Liang ◽  
Zengliang Ruan ◽  
Bipin Kumar Acharya ◽  
...  
Keyword(s):  
Air Pollution ◽  
Congenital Heart Defect ◽  
Congenital Heart ◽  
Heart Defect ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Indoor Air Quality Survey. Prepared for educational purposes based on real measurements made in May 25, 2014.

2018 ◽  
Author(s):  
Dmytro Varavin
Keyword(s):  
Air Pollution ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Indoor Air ◽  
Respiratory Infections ◽  
Chronic Obstructive ◽  
Outdoor Air ◽  
Acute Lower Respiratory Infections ◽  
Air Pollution Exposure ◽  
Pollution Exposure

In 2014, WHO reports that in 2012 around 7 million people died - one in eight of total global deaths – as a result of air pollution exposure. This finding more than doubles previous estimates and confirms that air pollution is now the world’s largest single environmental health risk. Reducing air pollution could save millions of lives. In particular, the new data reveal a stronger link between both indoor and outdoor air pollution exposure and cardiovascular diseases, such as strokes and ischaemic heart disease, as well as between air pollution and cancer. This is in addition to air pollution’s role in the development of respiratory diseases, including acute respiratory infections and chronic obstructive pulmonary diseases. Included in the assessment is a breakdown of deaths attributed to specific diseases, underlining that the vast majority of air pollution deaths are due to cardiovascular diseases as follows: Outdoor air pollution-caused deaths – breakdown by disease: 40% – ischaemic heart disease; 40% – stroke; 11% – chronic obstructive pulmonary disease (COPD); 6% - lung cancer; and 3% – acute lower respiratory infections in children. Indoor air pollution-caused deaths – breakdown by disease: 34% - stroke; 26% - ischaemic heart disease; 22% - COPD; 12% - acute lower respiratory infections in children; and 6% - lung cancer. “The risks from air pollution are now far greater than previously thought or understood, particularly for heart disease and strokes,” says Dr Maria Neira, Director of WHO’s Department for Public Health, Environmental and Social Determinants of Health. “Few risks have a greater impact on global health today than air pollution; the evidence signals the need for concerted action to clean up the air we all breathe.”

Maternal air pollution exposure and congenital heart defects in offspring: A systematic review and meta-analysis

Chemosphere ◽  
2020 ◽  
Vol 253 ◽  
pp. 126668 ◽  
Author(s):  
Cheng-Yang Hu ◽  
Kai Huang ◽  
Yuan Fang ◽  
Xiao-Jing Yang ◽  
Kun Ding ◽  
...  
Keyword(s):  
Systematic Review ◽  
Air Pollution ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Meta Analysis ◽  
Air Pollution Exposure ◽  
Pollution Exposure

The burden of ischemic heart disease related to ambient air pollution exposure in a coastal city in South China

2018 ◽  
Vol 164 ◽  
pp. 255-261 ◽  
Author(s):  
Jing Huang ◽  
Guoxing Li ◽  
Xujun Qian ◽  
Guozhang Xu ◽  
Yan Zhao ◽  
...  
Keyword(s):  
Air Pollution ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
South China ◽  
Ambient Air ◽  
Ischemic Heart ◽  
Ambient Air Pollution ◽  
Coastal City ◽  
Air Pollution Exposure ◽  
Pollution Exposure
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