Rapid IC–ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water

ICP-MS method was optimized for the simultaneous analysis of 16 metals (Pb, Cd, As, Hg, Sn, Sb, Co, Ni, Cr, Mn, Mo, Se, Cu, Fe, Zn , Al) in types of medicinal herbs commonly used to produce functional foods. The conditions of samples digestion in a closed system using a microwave and an opened system in Kjeldahl method have been studied in order to flexibly apply different methods of sample preparation in practice. The method was validated with parameters such as calibration curve, limit of detection, limit of quantitation, repeatability RSDr % (0.98 - 19.7%), reproducibility RSDR% (2.72 - 23.5%) and recovery R% (80.3 -109%) meeting the AOAC performance requirements. The method was applied to determine heavy metals in 40 samples of medicinal herbs of apart from the risk of pollution with some toxic heavy metals such as lead and cadmium in medicinal herbs.

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U–Th–Pb geochronology and simultaneous analysis of multiple isotope systems in geological samples by LA-MC-ICP-MS

Journal of Analytical Atomic Spectrometry ◽

10.1039/c8ja00157j ◽

2018 ◽

Vol 33 (10) ◽

pp. 1600-1615 ◽

Cited By ~ 3

Author(s):

Lie-Wen Xie ◽

Noreen J. Evans ◽

Yue-Heng Yang ◽

Chao Huang ◽

Jin-Hui Yang

Keyword(s):

Spatial Resolution ◽

Critical Review ◽

High Spatial Resolution ◽

Simultaneous Analysis ◽

Geological Samples ◽

Icp Ms

This is a critical review that: (i) provides an overview of LA-MC-ICP-MS dating techniques; (ii) highlights the benefits of using ICs and summarizes recent improvements in ultra-high spatial resolution dating; (iii) summarizes the range of minerals utilized for LA-MC-ICP-MS geochronology and LASS.

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Simultaneous analysis of 21 elements in foodstuffs by ICP-MS after closed-vessel microwave digestion: Method validation

Journal of Food Composition and Analysis ◽

10.1016/j.jfca.2010.04.002 ◽

2011 ◽

Vol 24 (1) ◽

pp. 111-120 ◽

Cited By ~ 66

Author(s):

Sandrine Millour ◽

Laurent Noël ◽

Ali Kadar ◽

Rachida Chekri ◽

Christelle Vastel ◽

...

Keyword(s):

Method Validation ◽

Microwave Digestion ◽

Simultaneous Analysis ◽

Closed Vessel ◽

Digestion Method ◽

Icp Ms

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Simultaneous Analysis of Iodine and Bromine Species in Infant Formula using HPLC-ICP-MS

Journal of AOAC International ◽

10.5740/jaoacint.18-0352 ◽

2019 ◽

Vol 102 (4) ◽

pp. 1199-1204 ◽

Cited By ~ 1

Author(s):

Jenny Nelson ◽

Lawrence Pacquette ◽

Shuofei Dong ◽

Michiko Yamanaka

Keyword(s):

Infant Formula ◽

Inductively Coupled Plasma ◽

Accurate Determination ◽

Simultaneous Analysis ◽

Triple Quadrupole ◽

Inductively Coupled ◽

Low Concentrations ◽

Icp Ms ◽

Halogen Species

Abstract Background: A fast and sensitive method for the simultaneous analysis of iodine and bromine species in infant formula was developed using HPLC–inductively coupled plasma–MS (HPLC-ICP-MS). Method: To determine the four halogen species [iodide (I−), iodate <inline-formula><mml:math display="inline"><mml:mrow><mml:mo>(</mml:mo><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">IO</mml:mi></mml:mrow><mml:mn>3</mml:mn><mml:mo>−</mml:mo></mml:msubsup></mml:mrow><mml:mo>)</mml:mo></mml:mrow></mml:math></inline-formula>, bromide (Br−), and bromate <inline-formula><mml:math display="inline"><mml:mrow><mml:mo>(</mml:mo><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">BrO</mml:mi></mml:mrow><mml:mn>3</mml:mn><mml:mo>−</mml:mo></mml:msubsup></mml:mrow><mml:mo>)</mml:mo></mml:mrow></mml:math></inline-formula>] in a milk-based Standard Reference Material and four commercially available infant formula products. Results: The four halogen species were baseline separated in less than 6.5 min using an anion exchange resin column and 5.0 mM NaH2PO4 / 15.0 mM Na2SO4 / 5.0 mM EDTA (pH 7.0) mobile phase. Following separation, the halogen species were detected by measuring m/z 79 for Br and m/z 127 for I using a triple quadrupole–ICP-MS. The instrument was operated in single quadrupole mode with helium cell gas. Excellent linearity (R = 0.9999 or better) was obtained for all four species with calibration standards ranging from 0 to 100 ppb. The LOD for I−, <inline-formula><mml:math display="inline"><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">IO</mml:mi></mml:mrow><mml:mn>3</mml:mn><mml:mo>−</mml:mo></mml:msubsup></mml:math></inline-formula>, Br−, and <inline-formula><mml:math display="inline"><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">BrO</mml:mi></mml:mrow><mml:mn>3</mml:mn><mml:mo>−</mml:mo></mml:msubsup></mml:math></inline-formula> were all less than 0.67 μg/kg. To test the suitability of the method for the accurate determination of low concentrations of the four species in infant formula samples, a spike recovery test was carried out at 20 and 40 μg/kg into the diluted infant formula samples. Conclusions: Total elemental determinations of iodine and bromine were also performed using the triple quadrupole–ICP-MS without HPLC.

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