To obtain high-entropy alloys (HEAS) coating with excellent properties on Q235 steel, a kind of HEAS powders was designed. The HEAS coating was prepared uniformly on Q235 steel by laser cladding. By means of OM, XRD and microhardness tester, the microstructure and properties of the high-entropy alloy layer were investigated. The experimental results indicate that the phases in the high-entropy alloy coating is mainly MoFeCrTiW with simple BCC, whose lattice parameter is a-3.1256Å. The microstructure in the coating is mainly cellular crystal, on which dispersion precipitates exist. And in the near bottom of the coating, there is few precipitates, in the middle part of coating, the precipitates are larger than that of bottom coating, while in near top of coating, dispersion precipitates become largest. The maximum microhardness value of coating reaches 800HV0.98.