Epidemiology of Erectile Dysfunction: the Role of Medical Comorbidities and Lifestyle Factors

2005 ◽  
Vol 32 (4) ◽  
pp. 403-417 ◽  
Author(s):  
Raymond C. Rosen ◽  
Rena Wing ◽  
Stephen Schneider ◽  
Noel Gendrano
Keyword(s):  
Erectile Dysfunction ◽  
Lifestyle Factors ◽  
Medical Comorbidities

scholarly journals Does the Interaction between Local and Systemic Inflammation Provide a Link from Psychology and Lifestyle to Tissue Health in Musculoskeletal Conditions?

2021 ◽  
Vol 22 (14) ◽  
pp. 7299
Author(s):  
David M. Klyne ◽  
Mary F. Barbe ◽  
Greg James ◽  
Paul W. Hodges
Keyword(s):  
Connective Tissue ◽  
Systemic Inflammation ◽  
Molecular Basis ◽  
Tissue Level ◽  
Lifestyle Factors ◽  
Local Inflammation ◽  
Musculoskeletal Conditions ◽  
Tissue Biology ◽  
Mind And Body

Musculoskeletal conditions are known to involve biological, psychological, social and, often, lifestyle elements. However, these domains are generally considered in isolation from each other. This siloed approach is unlikely to be adequate to understand the complexity of these conditions and likely explains a major component of the disappointing effects of treatment. This paper presents a hypothesis that aims to provide a foundation to understand the interaction and integration between these domains. We propose a hypothesis that provides a plausible link between psychology and lifestyle factors with tissue level effects (such as connective tissue dysregulation/accumulation) in musculoskeletal conditions that is founded on understanding the molecular basis for interaction between systemic and local inflammation. The hypothesis provides plausible and testable links between mind and body, for which empirical evidence can be found for many aspects. We present this hypothesis from the perspective of connective tissue biology and pathology (fibrosis), the role of inflammation locally (tissue level), and how this inflammation is shaped by systemic inflammation through bidirectional pathways, and various psychological and lifestyle factors via their influence on systemic inflammation. This hypothesis provides a foundation for new consideration of the development and refinement of personalized multidimensional treatments for individuals with musculoskeletal conditions.

scholarly journals Role of Glucose-Lowering Medications in Erectile Dysfunction

2021 ◽  
Vol 10 (11) ◽  
pp. 2501
Author(s):  
Angelo Cignarelli ◽  
Valentina Annamaria Genchi ◽  
Rossella D’Oria ◽  
Fiorella Giordano ◽  
Irene Caruso ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Current Knowledge ◽  
Smooth Muscle Contractility ◽  
Glucose Lowering ◽  
Glycation End Products ◽  
Altered Metabolism

Erectile dysfunction (ED) is a long-term complication of type 2 diabetes (T2D) widely known to affect the quality of life. Several aspects of altered metabolism in individuals with T2D may help to compromise the penile vasculature structure and functions, thus exacerbating the imbalance between smooth muscle contractility and relaxation. Among these, advanced glycation end-products and reactive oxygen species derived from a hyperglycaemic state are known to accelerate endothelial dysfunction by lowering nitric oxide bioavailability, the essential stimulus of relaxation. Although several studies have explained the pathogenetic mechanisms involved in the generation of erectile failure, few studies to date have described the efficacy of glucose-lowering medications in the restoration of normal sexual activity. Herein, we will present current knowledge about the main starters of the pathophysiology of diabetic ED and explore the role of different anti-diabetes therapies in the potential remission of ED, highlighting specific pathways whose activation or inhibition could be fundamental for sexual care in a diabetes setting.

scholarly journals Consumer acceptance of high pressure processed beef-based chilled ready meals: The mediating role of food-related lifestyle factors

Meat Science ◽  
2011 ◽  
Vol 87 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Douglas Sorenson ◽  
Maeve Henchion ◽  
Begonya Marcos ◽  
Paddy Ward ◽  
Anne Maria Mullen ◽  
...  
Keyword(s):  
High Pressure ◽  
Lifestyle Factors ◽  
Consumer Acceptance ◽  
Mediating Role

scholarly journals Erectile dysfunction – overview from a cardiovascular perspective

VASA ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 347-353 ◽  
Author(s):  
Frederic Baumann ◽  
Deborah Hehli ◽  
Vladimir Makaloski ◽  
Martin Schumacher ◽  
Heinz Schönhofen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Erectile Dysfunction ◽  
Cardiovascular Risk ◽  
Endovascular Therapy ◽  
Minimal Invasive ◽  
Male Population ◽  
Ageing Male ◽  
The Common ◽  
Diagnostics And Therapy

Abstract. Erectile dysfunction (ED) is an evolving health problem with growing incidence in the ageing male population with potentially predictive value for cardiovascular and other chronic diseases. ED shares the common cardiovascular risk factors. The aetiology of ED is numerous including neurogenic, psychogenic, arteriogenic, and venogenic reasons. The origin of arteriogenic ED is frequently atherosclerosis. Patients not adequately responding to conservative measures including oral medication are often referred to further vascular diagnostics and therapy. At present, the refinements in endovascular therapy allow for minimal-invasive revascularization of erection-related arteries. The role of endovascular therapy in the complex framework of the multifactorial causes of ED requires further scientific scrutiny.

Aetiology and progression of cancer

2016 ◽  
pp. 155-159
Author(s):  
Fränzel J.B. van Duijnhoven ◽  
Ellen Kampman
Keyword(s):  
Physical Activity ◽  
Cancer Progression ◽  
Lifestyle Factors ◽  
Evidence Based ◽  
Unhealthy Lifestyle ◽  
Body Fatness ◽  
Treatment Research ◽  
After Cancer ◽  
Risk Of Cancer

Worldwide, there is a large difference in cancer rates. These rates may change over generations when people move from one part of the world to another. This occurs because these generations adapt their lifestyle to that of the host country, indicating that lifestyle factors are important in the aetiology of cancer. In this chapter an overview of established associations between body fatness, physical activity, diet, and other lifestyle factors and the development of cancer is given. About one-third of all cancers worldwide are caused by an unhealthy lifestyle. Evidence-based recommendations for the general population to decrease their risk of cancer have been set. Guidelines for individuals who are diagnosed with cancer, however, are lacking, due to limited evidence on the role of lifestyle during and after cancer treatment. Research should now be directed towards the role of body fatness, physical activity, diet, and other lifestyle factors in cancer progression.

Sign in / Sign up

Export Citation Format

Share Document