Flexible Ureterorenoscopy Is Safe and Efficient for the Treatment of Kidney Stones in Patients With Chronic Kidney Disease

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.

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Removal of Kidney Stones by Extracorporeal Shock Wave Lithotripsy Is Associated with Delayed Progression of Chronic Kidney Disease

Yonsei Medical Journal ◽

10.3349/ymj.2012.53.4.708 ◽

2012 ◽

Vol 53 (4) ◽

pp. 708 ◽

Cited By ~ 5

Author(s):

Dong Eun Yoo ◽

Seung Hyeok Han ◽

Hyung Jung Oh ◽

Seung Jun Kim ◽

Dong Ho Shin ◽

...

Keyword(s):

Shock Wave ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Stones ◽

Extracorporeal Shock Wave Lithotripsy ◽

Shock Wave Lithotripsy ◽

Extracorporeal Shock Wave

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History of kidney stones and risk of chronic kidney disease: a meta-analysis

PeerJ ◽

10.7717/peerj.2907 ◽

2017 ◽

Vol 5 ◽

pp. e2907 ◽

Cited By ~ 9

Author(s):

Weifeng Shang ◽

Lixi Li ◽

Yali Ren ◽

Qiangqiang Ge ◽

Ming Ku ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Stones ◽

Meta Analysis ◽

Positive Association ◽

Significant Heterogeneity ◽

Adjusted Risk ◽

Increased Risk ◽

Subgroup Analyses ◽

History Of

Background Although the relationship between a history of kidney stones and chronic kidney disease (CKD) has been explored in many studies, it is still far from being well understood. Thus, we conducted a meta-analysis of studies comparing rates of CKD in patients with a history of kidney stones. Methods PubMed, EMBASE, and the reference lists of relevant articles were searched to identify observational studies related to the topic. A random-effects model was used to combine the study-specific risk estimates. We explored the potential heterogeneity by subgroup analyses and meta-regression analyses. Results Seven studies were included in this meta-analysis. Pooled results suggested that a history of kidney stones was associated with an increased adjusted risk estimate for CKD [risk ratio (RR), 1.47 95% confidence interval (CI) [1.23–1.76])], with significant heterogeneity among these studies (I2 = 93.6%, P < 0.001). The observed positive association was observed in most of the subgroup analyses, whereas the association was not significant among studies from Asian countries, the mean age ≥50 years and male patients. Conclusion A history of kidney stones is associated with increased risk of CKD. Future investigations are encouraged to reveal the underlying mechanisms in the connection between kidney stones and CKD, which may point the way to more effective preventive and therapeutic measures.

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Plant-Based Milk Alternatives and Risk Factors for Kidney Stones and Chronic Kidney Disease

Journal of Renal Nutrition ◽

10.1053/j.jrn.2021.03.011 ◽

2021 ◽

Author(s):

James F. Borin ◽

John Knight ◽

Ross P. Holmes ◽

Shivam Joshi ◽

David S. Goldfarb ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Stones

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Risk Factors for Chronic Kidney Disease

Kidney Protection ◽

10.1093/med/9780190611620.003.0004 ◽

2019 ◽

pp. 29-38

Author(s):

Hania Kassem ◽

Bernard G. Jaar

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Stones ◽

Developed Countries ◽

Modifiable Risk Factors ◽

Public Health Burden ◽

Obstructive Sleep ◽

Significant Public Health ◽

Common Risk Factors

Chronic kidney disease (CKD) represents a significant public health burden worldwide and several risk factors have been identified over the years; these have been well-described in the medical literature. Common risk factors such as diabetes mellitus and hypertension will be described in other chapters. While this chapter will focus mainly on CKD risk factors observed in developed countries, several of these are also observed in developing countries. It is now well-established that some risk factors are modifiable while others are non-modifiable. In this chapter, we will explore several of these non-modifiable risk factors in more detail, such as age, gender, race, family history, and low birth weight. But we will also discuss some of the modifiable risk factors such as kidney stones, obstructive sleep apnea, smoking, drugs (excluding NSAIDs), diet, obesity, metabolic syndrome, and hyperuricemia. We will provide a balanced and up to date review of the evidence linking these risk factors with CKD.

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Risk of chronic kidney disease in patients with kidney stones—A nationwide cohort study

10.21203/rs.3.rs-25969/v1 ◽

2020 ◽

Author(s):

Tzung-Fang Chuang ◽

Hung-Chang Hung ◽

Shu-Fen Li ◽

Mei-Wen Li ◽

Chin-Tun Hung

Keyword(s):

Chronic Kidney Disease ◽

Risk Factor ◽

Cohort Study ◽

Kidney Disease ◽

Kidney Stones ◽

Kidney Stone ◽

Population Based ◽

Control Group ◽

Self Awareness ◽

Stone Formers

Abstract Background Chronic kidney disease (CKD) and kidney stones are common in Taiwan; in particular, CKD has a high prevalence but low self-awareness rate. CKD-related risk factors such as diabetes, hypertension, and nephrotoxic drugs are well-known and uncontested; however, kidney stones are relatively less studied and easily overlooked as a risk factor. The objective of this study was to investigate whether kidney stones are a risk factor for CKD.Methods We conducted a nationwide population-based matched cohort study to assess the risk of incident CKD in people with kidney stones. Data on incident stones formers in the year 2001—excluding those with a history of CKD—were obtained from Taiwan’s National Health Insurance database. Stone formers were matched (1:4) to control subjects according to sex, age, and index date. The total observation period of the study was 10 years, and the primary end-point was the occurrence of CKD. Student’s t-test and Chi-squared test were used to compare continuous and categorical data, respectively. Logistic regression was used to calculate the odds ratio of kidney stone patients with incident CKD relative to the control group. Cox proportional hazard regression model was used to obtain the hazards ratio for development of incident CKD among patients with kidney stones.Results The incidence of CKD in the kidney stone cohort was 11.2%, which was significantly higher than that of the control group (P < .001). Survival analysis showed that the stones cohort was 1.82 times more likely to experience CKD than the controls. Age, sex, hypertension, diabetes mellitus, and hyperlipidemia increased the risk of CKD incidence (1.04, 1.27, 1.55, 3.31, and 1.25 times, respectively).Conclusion Kidney stones are a definite risk factor for CKD; therefore, patients with stones are suggested to undergo regular renal function monitoring and receive appropriate treatment to avoid CKD.

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