scholarly journals Hepatitis E virus: Animal reservoirs and zoonotic risk

2010 ◽  
Vol 140 (3-4) ◽  
pp. 256-265 ◽  
Author(s):  
X.J. Meng
2021 ◽  
Author(s):  
Andrea Palombieri ◽  
Ilia Tsachev ◽  
Vittorio Sarchese ◽  
Paola Fruci ◽  
Federica Di Profio ◽  
...  

Abstract Information on hepatitis E virus (HEV) epidemiology in animal reservoirs in Bulgaria is still lacking. Herein, by screening HEV seropositive sera obtained from Bulgarian swine and wild boars, viral RNA was detected at high prevalence rate (28.2%) in industrial pigs. Sequence analysis of the partial polymerase (RdRp) region revealed the highest genetic correlation with HEVs of genotype (Gt) 3 identified in French and Dutch patients. For three such strains a 700-bp fragment of the ORF 2 gene was generated. On phylogenetic analysis, the Bulgarian strains clustered tightly (93.8-98.3% nt) with human and animal HEVs classified within the Gt3 subtype c.


2009 ◽  
Vol 39 (12) ◽  
pp. 1153-1158 ◽  
Author(s):  
Yibin Chang ◽  
Ling Wang ◽  
Jiabao Geng ◽  
Yonghong Zhu ◽  
Hongwei Fu ◽  
...  

Viruses ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 270 ◽  
Author(s):  
Virginie Doceul ◽  
Eugénie Bagdassarian ◽  
Antonin Demange ◽  
Nicole Pavio

Viruses ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1429
Author(s):  
Radka Dziedzinska ◽  
Miroslava Krzyzankova ◽  
Marcel Bena ◽  
Petra Vasickova

Hepatitis E virus (HEV) is the etiological agent behind hepatitis E infection. Domestic pigs and wild boars are the main animal reservoirs of HEV. Very few papers describe HEV infection in goats and sheep. As the data pertaining to the presence of HEV virus in the milk of small ruminants in Europe are lacking, the aim of this paper was to examine a representative number of milk samples from these animals. The detection of HEV genome (HEV RNA) was performed using reverse transcriptase real-time polymerase chain reaction (RT-qPCR). HEV RNA was found in 2.8% of the examined samples. Positivity ranged from 101 to 103 genome equivalents/mL (GE/mL) with a median of 9.99 × 102 GE/mL. On the basis of these results, the milk of small ruminants could represent a source of HEV infection to consumers.


Pathogens ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 154 ◽  
Author(s):  
Bo Wang ◽  
Dominik Harms ◽  
Xing-Lou Yang ◽  
C.-Thomas Bock

Hepatitis E virus (HEV) is an emerging zoonotic pathogen that has received an increasing amount of attention from virologists, clinicians, veterinarians, and epidemiologists over the past decade. The host range and animal reservoirs of HEV are rapidly expanding and a plethora of emerging HEV variants have been recently identified, some of which have the potential for interspecies infection. In this review, the detection of genetically diverse HEV variants, classified into and presumably associated with the species Orthohepevirus C, currently comprising HEV genotypes C1 and C2, by either serological or molecular approach is summarized. The distribution, genomic variability, and evolution of Orthohepevirus C are analyzed. Moreover, the potential risk of cross-species infection and zoonotic transmission of Orthohepevirus C are discussed.


2021 ◽  
Vol 8 (11) ◽  
pp. 267
Author(s):  
Andrea Palombieri ◽  
Ilia Tsachev ◽  
Vittorio Sarchese ◽  
Paola Fruci ◽  
Federica Di Profio ◽  
...  

Information on hepatitis E virus (HEV) strains circulating in animal reservoirs in Bulgaria is currently lacking. Herein, by screening HEV seropositive sera obtained from Bulgarian swine and wild boars, viral RNA was detected at high prevalence rate (28.2%) in industrial pigs. Sequence analysis of the partial polymerase (RdRp) region revealed the highest genetic correlation with HEVs of genotype (Gt) 3 identified in French and Dutch patients. For three such strains, a 700-bp fragment of the open reading frame 2 gene was generated. On phylogenetic analysis, the Bulgarian strains clustered tightly (93.8–98.3% nt) with human and animal HEVs classified within the Gt3 subtype c.


2019 ◽  
Vol 11 (2) ◽  
pp. 87-94
Author(s):  
Arief Mulyono ◽  
Tika Fiona Sari ◽  
Ristiyanto Ristiyanto ◽  
Bernadus Yuliadi ◽  
Edi Royandi ◽  
...  

Rats are animal reservoirs and harbours of several zoonotic pathogens diseases in humans. At least, there are 68 viruses of zoonotic agents that can be transmitted by rats. Two common types of viruses attackinghumans are Hepatitis E virus (HEV) and Hantavirus. Early detection of those viruses is fundamentally required in order to prevent disease transmissions to humans. The aim of the study was to detect and count the percentage of rats infected by HEV and Hantavirus in Kendal and Klaten Districts, Central Java Province. The research design used in this study was descriptive design with cross-sectional approach. The target population was rats distributed in Klaten and Kendal Districts. In addition, the research subject was trapped rats. Detection of Hantavirus was carried out using ELISA method and detection of HEV was conducted using nested reverse transcription PCR (nested RT-PCR). A total of 73 rats was successfully captured consisting of 2 genus and 4 species e.g. Rattus novergicus, R. tanezumi, R. tiomanicus and Bandicota indica. The trapped rats infected by HEV were 3.7% and 41.3% for Klaten and Kendal, respectively. However, the seropositive of Hantavirus was only found in Kendal District (20.5%). Rat control is necessary to prevent transmission of HEV and Hantavirus.


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