Clinical Presentation and Pathologic Characteristics of Pituitary Metastasis from Breast Carcinoma: Cases and a Systematic Review of the Literature

2019 ◽  
Vol 124 ◽  
pp. 445-451.e2 ◽  
Author(s):  
Heng Cai ◽  
Wenjing Liu ◽  
Tianda Feng ◽  
Zhen Li ◽  
Yunhui Liu
Keyword(s):  
Systematic Review ◽  
Breast Carcinoma ◽  
Clinical Presentation ◽  
Review Of The Literature ◽  
Pituitary Metastasis

Recurring Intracranial Malignant Peripheral Nerve Sheath Tumor: Case Report and Systematic Review of the Literature

Neurosurgery ◽  
2011 ◽  
Vol 68 (4) ◽  
pp. E1152-E1159 ◽  
Author(s):  
Pepijn van den Munckhof ◽  
Menno R. Germans ◽  
Antoinette Y. N. Schouten-van Meeteren ◽  
Foppe Oldenburger ◽  
Dirk Troost ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Presentation ◽  
Cranial Nerves ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Nerve Sheath Tumor ◽  
Review Of The Literature ◽  
En Bloc ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Abstract BACKGROUND AND IMPORTANCE: To report the clinical presentation and management of an intracranial frontoparietal malignant peripheral nerve sheath tumor (MPNST) and its recurrence in a 6-year-old girl, along with a systematic review of the literature. CLINICAL PRESENTATION: A previously healthy 6-year-old girl presented with severe signs of increased intracranial pressure. Magnetic resonance imaging (MRI) revealed a large heterogeneously enhancing mass at the right frontoparietal convexity. The tumor was completely removed, the histological diagnosis was MPNST, and the patient underwent adjuvant radio- and chemotherapy. Fifteen months later, MRI revealed a small local recurrence. After upfront chemotherapy, the recurrence was removed in a radical, ie, true oncological, neuronavigationally guided, en bloc resection, including approximately 1 cm surrounding gray and white matter and overlying dura mater. Neuropathological examination revealed tumor-free margins. The patient again received adjuvant chemotherapy. Four years after diagnosis and 20 months after cessation of adjuvant therapy, there are no signs of tumor recurrence. The literature search resulted in 17 cases of intracranial MPNSTs not associated with cranial nerves. Despite macroscopically complete resection in many cases and adjuvant radio- and chemotherapy, overall survival was poor, with only 5 patients still alive upon publication (including the current patient). CONCLUSION: Intracranial MPNSTs not associated with cranial nerves are extremely rare and highly malignant tumors with poor overall survival, probably because of infiltrating growth into surrounding brain tissue. We therefore advocate consideration of nonconventional true oncological en bloc resection when approaching this rare tumor or its recurrence.

scholarly journals Endometriosis of the Canal of Nuck: A Systematic Review of the Literature

Diagnostics ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 3
Author(s):  
Anastasia Prodromidou ◽  
Anastasios Pandraklakis ◽  
Alexandros Rodolakis ◽  
Nikolaos Thomakos
Keyword(s):  
Systematic Review ◽  
Overall Survival ◽  
Clinical Presentation ◽  
Uterine Cavity ◽  
Reproductive Age ◽  
Thoracic Cavity ◽  
Review Of The Literature ◽  
Diagnostic Features ◽  
The Common ◽  
Groin Swelling

Endometriosis is a common benign gynecological condition defined as the presence of endometrial tissue in tissues outside the uterine cavity. Apart from the common sites of endometriosis, rare sites other have also been reported including the liver, the thoracic cavity, the muscles, nerves, and more rarely in a patent Nuck canal. We aim to evaluate the clinical presentation, diagnostic features, and management of the Nuck endometriosis. A meticulous search of three electronic databases was performed until May 2020 for articles reporting cases of Nuck endometriosis. A total of 36 patients from 20 studies were analyzed. Median age of patients was 36 years with 33 women being of reproductive age. A right-sided lesion was identified in 30 cases (83.3%), while all patients suffer from a groin mass with cyclic pain in a proportion of 22%. All the patients finally underwent surgery for investigation of the lesion and fixation of the defect. Five cases of malignancy were detected at final pathology. All of them were alive with a median reported overall survival of 37 months. Nuck endometriosis should be included in the differential diagnosis of female patients with groin swelling. An evaluation by a gynecologist is important when endometriosis is suspected.

scholarly journals Esophageal Lipoma and Liposarcoma: A Systematic Review

2020 ◽  
Vol 45 (1) ◽  
pp. 225-234
Author(s):  
Davide Ferrari ◽  
Daniele Bernardi ◽  
Stefano Siboni ◽  
Veronica Lazzari ◽  
Emanuele Asti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Open Surgery ◽  
Clinical Presentation ◽  
Tumor Location ◽  
Radiological Imaging ◽  
Electronic Database ◽  
Review Of The Literature ◽  
Submucosal Tumors ◽  
Size And Morphology ◽  
Lipomatous Tumors

Abstract Background Esophageal lipomatous tumors, also reported as fibrovascular polyp, fibrolipoma, angiolipoma, and liposarcoma, account for less than 1% of all benign mesenchymal submucosal tumors of the esophagus. Clinical presentation and therapy may differ based on location, size, and morphology. A comprehensive and updated systematic review of the literature is lacking. Methods A systematic review of the literature was performed according to PRISMA guidelines. Pubmed, Embase, Cochrane, and Medline databases were consulted using MESH keywords. Non-English written articles and abstracts were excluded. Sex, age, symptoms at presentation, diagnosis, tumor location and size, surgical approach and technique of excision, pathology, and morphology were extracted and recorded in an electronic database. Results Sixty-seven studies for a total of 239 patients with esophageal lipoma or liposarcoma were included in the qualitative analysis. Among 176 patients with benign lipoma, the median age was 55. The main symptoms were dysphagia (64.2%), transoral polyp regurgitation (32.4%), and globus sensation (22.7%). The majority of lipomas (85.7%) were intraluminal polyps, with a stalk originating from the upper esophagus. Overall, 165 patients underwent excision of the mass through open surgery (65.5%), endoscopy (27.9%), or laparoscopy/thoracoscopy (3.6%). Only 5 (3%) of patients required esophagectomy. Of the 11 untreated patients with an intraluminal polyp, 7 died from asphyxia. Overall, liposarcoma was diagnosed in 63 patients, and 12 (19%) underwent esophagectomy. Conclusion Esophageal lipomatous tumors are rare but potentially lethal when are intraluminal and originate from the cervical esophagus. Modern radiological imaging has improved diagnostic accuracy. Minimally invasive transoral and laparoscopic/thoracoscopic techniques represent the therapeutic approach of choice.

Metaplastic breast carcinoma: A case report and systematic review of the literature

2011 ◽  
Vol 61 (10) ◽  
pp. 582-588 ◽  
Author(s):  
Zaher Toumi ◽  
Caroline Bullen ◽  
Albert C. S. Tang ◽  
Neha Dalal ◽  
Simon Ellenbogen
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Breast Carcinoma ◽  
Review Of The Literature ◽  
Metaplastic Breast Carcinoma

scholarly journals Insulinoma in pregnancy (a case presentation and systematic review of the literature)

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132098664
Author(s):  
Eva M Dobrindt ◽  
Martina Mogl ◽  
Peter E Goretzki ◽  
Johann Pratschke ◽  
Agata K Dukaczewska
Keyword(s):  
Systematic Review ◽  
Early Pregnancy ◽  
Clinical Presentation ◽  
Post Partum ◽  
Clinical Signs ◽  
Hyperinsulinemic Hypoglycemia ◽  
Second Trimester ◽  
Review Of The Literature ◽  
Case Presentation ◽  
In Pregnancy

Insulinomas are rare, benign and functional tumors that coincidentally may become overt during pregnancy or in the post-partum period. As the general symptoms of a pregnancy might cover the clinical presentation, diagnosing remains challenging. We present one additional case of a post-partum insulinoma, combined with a systematic review of the literature to sum up relevant details in diagnosis and treatment. A systematic request of Pubmed/Medline was conducted using the following terms: “insulinoma AND pregnancy” and “insulinoma” for a second request of ClinicalTrials.gov. All publications concerning pregnant or post-partum women with insulinoma were included. Thirty-six cases could be identified for analysis. Each publication was reviewed for demographic, diagnostic and therapeutic data. The most frequent clinical signs were unconsciousness and neurological symptoms. 64.9% were diagnosed during early pregnancy and 35.1% post-partum. 91.9% underwent surgery with a third resected during pregnancy without severe influence on fetal or maternal outcome. Three patients died of metastatic disease or misdiagnosing, two of them miscarried. Insulinoma in pregnancy is rare but should be considered in case of unclear hyperinsulinemic hypoglycemia. Surgery can be performed during the second trimester or post-partum with promising outcome.

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