ERK-mediated upregulation of matrix metalloproteinase-2 promotes the invasiveness in human oral squamous cell carcinoma (OSCC)

2021 ◽  
pp. 112984
Author(s):  
Kamdeo Kumar Pramanik ◽  
Rajakishore Mishra
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Matrix Metalloproteinase ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Matrix Metalloproteinase 2

scholarly journals Molecular docking of alkaloid compounds with the matrix metalloproteinase 2

2021 ◽  
Vol 17 (1) ◽  
pp. 206-211
Author(s):  
JH Shazia Fathima ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Molecular Docking ◽  
Oral Squamous Cell Carcinoma ◽  
Matrix Metalloproteinase ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aristolochic Acid ◽  
Matrix Metalloproteinase 2 ◽  
The Matrix

Matrix metalloproteinase protein-2 (MMP-2) is linked to the human oral squamous cell carcinoma. Therefore, it is of interest to design new inhibitors for MMP-2 to combat the disease. Thus, we document the molecular docking features of Aristolochic acid, Cryptopleurine, Epipodophyllotoxin, and Fagaronine with MMP-2 for further consideration.

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