scholarly journals Imaging of the membrane surface of MDCK cells by atomic force microscopy

1994 ◽  
Vol 67 (1) ◽  
pp. 36-41 ◽  
Author(s):  
C. Le Grimellec ◽  
E. Lesniewska ◽  
C. Cachia ◽  
J.P. Schreiber ◽  
F. de Fornel ◽  
...  
2000 ◽  
Vol 39 (Part 1, No. 6B) ◽  
pp. 3711-3716 ◽  
Author(s):  
Hatsuki Shiga ◽  
Yukako Yamane ◽  
Etsuro Ito ◽  
Kazuhiro Abe ◽  
Kazushige Kawabata ◽  
...  

1992 ◽  
Vol 46 (1) ◽  
pp. 167-178 ◽  
Author(s):  
A. K. Fritzsche ◽  
A. R. Arevalo ◽  
M. D. Moore ◽  
C. J. Weber ◽  
V. B. Elings ◽  
...  

2002 ◽  
Vol 01 (05n06) ◽  
pp. 683-688 ◽  
Author(s):  
YONG CHEN ◽  
JIYE CAI ◽  
JINGXIAN ZHAO

In recent years, many mammalian cells, especially erythrocytes because of simpleness of their membrane surfaces, were widely studied by atomic force microscopy. In our study, diseased erythrocytes were taken from patients of lung cancer, myelodisplastic syndrome (MDS), and so on. We obtained many clear topographical images of numerous erythrocytes, single erythrocyte, and ultramicrostructure of erythrocyte membrane surfaces from normal persons and patients. By studying the red cells of lung cancer patients, we found that many erythrocytes of lung cancer patient have changed into echinocytes. One erythrocyte has 10–20 short projections, most of which, with a mean width of 589.0 nm and a length of 646.7 nm, are on the edge of cell. The projections in the center of echinocytes are lodged and embedded, but in conventional model of echinocytes, the projections in the center stretch outside cell membrane, so a novel model of erythrocytes was designed in our paper. After observation of microstructure of MDS patient's erythrocyte membrane surface, we found that many apertures with different diameters of tens to hundreds nanometers appeared on the surface of cell membrane. It can be concluded that AFM may be widely applied in clinic pathological inspection.


1996 ◽  
Vol 52 (12) ◽  
pp. 660-663
Author(s):  
Yoshiaki Hayashi ◽  
Tatsuji Murata ◽  
Akihiko Tanioka

FEBS Letters ◽  
2004 ◽  
Vol 565 (1-3) ◽  
pp. 53-58 ◽  
Author(s):  
Kate Poole ◽  
Doris Meder ◽  
Kai Simons ◽  
Daniel Müller

2009 ◽  
Vol 148 (3) ◽  
pp. 455-460 ◽  
Author(s):  
A. M. Chernysh ◽  
E. K. Kozlova ◽  
V. V. Moroz ◽  
P. Yu. Borshagovskaya ◽  
U. A. Bliznuk ◽  
...  

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