Sa1395 - Factors Influencing Length of Hospital Stay in Mild Acute Pancreatitis

Introduction: Severe acute pancreatitis, according to Atlanta classification, is a heterogeneous group of patients with different outcomes. The patients with local complications and without organ failure have better outcome. This study has been conducted to determine the proportion of moderately severe acute pancreatitis and validate this subgroup in our population of patients.Methods: A total of 172 patients with the diagnosis of acute pancreatitis were categorized into three groups according to presence or absence of local complications and organ failure as mild acute pancreatitis, moderately severe acute pancreatitis and severe acute pancreatitis and were compared in terms of need for intensive care unit care, length of ICU stay, need for intervention, length of hospital stay and mortality.Results: Fifty seven (33%) were categorized as moderately severe acute pancreatitis. Need for ICU care (19.3% vs 100%, p < 0.001), length of ICU stay (1 vs 9.8 days, p < 0.001), length of hospital stay (8.3±3.7 vs 16.6±8.1 days, p < 0.001) and mortality (0% vs 33.3%, p < 0.001) between moderately severe acute pancreatitis and severe acute pancreatitis was significantly different. Moreover, mild acute pancreatitis and moderately severe acute pancreatitis had no mortality.Conclusions: This study showed that moderately severe acute pancreatitis exists as a separate group different from mild acute pancreatitis and severe acute pancreatitis with no mortality as in mild acute pancreatitis. Keywords: moderately severe acute pancreatitis; Atlanta classification; outcome.

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SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study

Gut ◽

10.1136/gutjnl-2020-323364 ◽

2021 ◽

pp. gutjnl-2020-323364

Author(s):

Sanjay Pandanaboyana ◽

John Moir ◽

John S Leeds ◽

Kofi Oppong ◽

Aditya Kanwar ◽

...

Keyword(s):

Acute Pancreatitis ◽

Hospital Stay ◽

Organ Failure ◽

Collaborative Study ◽

Length Of Hospital Stay ◽

Secondary Outcome ◽

Icu Admission ◽

Local Complications ◽

Persistent Organ Failure ◽

Increased Risk

ObjectiveThere is emerging evidence that the pancreas may be a target organ of SARS-CoV-2 infection. This aim of this study was to investigate the outcome of patients with acute pancreatitis (AP) and coexistent SARS-CoV-2 infection.DesignA prospective international multicentre cohort study including consecutive patients admitted with AP during the current pandemic was undertaken. Primary outcome measure was severity of AP. Secondary outcome measures were aetiology of AP, intensive care unit (ICU) admission, length of hospital stay, local complications, acute respiratory distress syndrome (ARDS), persistent organ failure and 30-day mortality. Multilevel logistic regression was used to compare the two groups.Results1777 patients with AP were included during the study period from 1 March to 23 July 2020. 149 patients (8.3%) had concomitant SARS-CoV-2 infection. Overall, SARS-CoV-2-positive patients were older male patients and more likely to develop severe AP and ARDS (p<0.001). Unadjusted analysis showed that SARS-CoV-2-positive patients with AP were more likely to require ICU admission (OR 5.21, p<0.001), local complications (OR 2.91, p<0.001), persistent organ failure (OR 7.32, p<0.001), prolonged hospital stay (OR 1.89, p<0.001) and a higher 30-day mortality (OR 6.56, p<0.001). Adjusted analysis showed length of stay (OR 1.32, p<0.001), persistent organ failure (OR 2.77, p<0.003) and 30-day mortality (OR 2.41, p<0.04) were significantly higher in SARS-CoV-2 co-infection.ConclusionPatients with AP and coexistent SARS-CoV-2 infection are at increased risk of severe AP, worse clinical outcomes, prolonged length of hospital stay and high 30-day mortality.

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P0032 VARIABLES AFFECTING LENGTH OF HOSPITAL STAY AND MORTALITY IN PATIENTS WITH ACUTE PANCREATITIS

European Journal of Internal Medicine ◽

10.1016/s0953-6205(09)60052-2 ◽

2009 ◽

Vol 20 ◽

pp. S19-S20

Author(s):

José Antonio Díaz-Peromingo ◽

Paula María Pesqueira-Fontán ◽

Marina Iglesias-Gallego ◽

Sonia Molinos-Castro ◽

Juan Saborido-Froján ◽

...

Keyword(s):

Acute Pancreatitis ◽

Hospital Stay ◽

Length Of Hospital Stay

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Tu1144 Comparison of Length of Hospital Stay of Children Admitted With Acute Pancreatitis Among Hospital Services At a Single Pediatric Tertiary Care Center

Gastroenterology ◽

10.1016/s0016-5085(14)62765-7 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-765 ◽

Cited By ~ 1

Author(s):

Flora K. Szabo ◽

Joseph J. Palermo ◽

Tom K. Lin ◽

Maisam Abu-El-Haija

Keyword(s):

Acute Pancreatitis ◽

Hospital Stay ◽

Care Center ◽

Tertiary Care ◽

Length Of Hospital Stay ◽

Tertiary Care Center ◽

Hospital Services

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Role of early enteral feeding in mild and moderate acute pancreatitis

International Surgery Journal ◽

10.18203/2349-2902.isj20214376 ◽

2021 ◽

Vol 8 (11) ◽

pp. 3387

Author(s):

Aswin George Roy ◽

Haridas T. V.

Keyword(s):

Acute Pancreatitis ◽

Hospital Stay ◽

Enteral Feeding ◽

Significant Risk ◽

Length Of Hospital Stay ◽

Advantages And Disadvantages ◽

Early Enteral Feeding ◽

Systemic Complication ◽

Infective Complications

Background: Timing of enteral feeding in acute pancreatitis was always a matter of controversy. Increasing evidence suggests that early enteral feeding reduces systemic and local complications of pancreatitis and thereby hospital stay. Hence the study has been undertaken to determine the feasibility, advantages and disadvantages of early enteral feeding in mild and moderate acute pancreatitis. Methods: Patients admitted with symptoms and signs suggestive of mild and moderate acute pancreatitis who were started on early enteral feeding (within 48 hours of admission) were included in study. Blood investigation results are used to classify patients accordingly to mild and moderate acute pancreatitis based on Ransons’s score. Patients were followed up and categorized based on development of complications, length of hospital stay.Results: Majority of the patients who were started on early enteral feeding showed significant decrease in complications and hospital stay. Study also suggested that age is a significant risk in development of complications. Gender is not significant in the development of complications.Conclusions: There is significant decrease in rate of systemic complication, local infective and non-infective complications, length of hospital stay among acute pancreatitis patients who were started on early enteral feeding (within 48 hours).

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Factors influencing the length of hospital stay of patients with substance use disorders

Journal of Substance Use ◽

10.1080/14659891.2020.1766130 ◽

2020 ◽

pp. 1-5

Author(s):

Louise Penzenstadler ◽

Anne Chatton ◽

Gabriel Thorens ◽

Daniele Zullino ◽

Yasser Khazaal

Keyword(s):

Substance Use ◽

Hospital Stay ◽

Substance Use Disorders ◽

Length Of Hospital Stay ◽

Factors Influencing

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B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis

Gastroenterology Research and Practice ◽

10.1155/2019/7568410 ◽

2019 ◽

Vol 2019 ◽

pp. 1-13 ◽

Cited By ~ 1

Author(s):

Xin Wei ◽

Weifeng Yao ◽

Huiping Li ◽

Jingjing Qian ◽

Yaosheng Xie ◽

...

Keyword(s):

Acute Pancreatitis ◽

B Cells ◽

Hospital Stay ◽

B Cell ◽

Nk Cells ◽

Length Of Hospital Stay ◽

Absolute Number ◽

Frequency Change ◽

Short Term Treatment ◽

Cell Frequency

Purpose. Pancreatitis can lead to systemic inflammatory response, but the relationship between lymphocyte changes and patients with pancreatitis remains unclear. In this study, we evaluated the feedback function of changes in peripheral lymphocyte subsets on the condition of patients with pancreatitis. Materials and Methods. 131 acute pancreatitis (AP) patients and 11 chronic pancreatitis (CP) patients constituted the patients’ group; 20 healthy individuals were enrolled as healthy controls (HC). Serum concentration of C-reactive protein (CRP), amylase, and lipase and the frequency and absolute number of many types of peripheral lymphocytes (including T, B, NK, CD16+/CD56+ T, CD4+ T, CD8+ T, CD4+CD8+ T, and CD4−CD8− T cells) were detected on admission and the seventh day of standard treatment. Besides, the length of hospital stay was recorded. Results. The absolute number of all lymphocytes we studied decreased in patients with CP and in patients with almost all types of AP. The frequency change of lymphocytes varies among the different types of AP. During disease onset, B cell frequency correlated positively with CRP concentration and NK cell frequency correlated positively with amylase and lipase concentration. B cell frequency and CD4+ T cell absolute number were recovering towards normal after short-term treatment. The frequency of B cells and NK cells correlated positively with the length of hospital stay. Conclusions. B cells and NK cells closely correlate with patients’ condition and may help to diagnose AP more accurately and reflect treatment effect of AP in time, affecting the recovery speed of patients with M-AP, which may help physicians to better understand the pathophysiology of pancreatitis.

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1323 Assessment of The Appropriate Use of Imaging and Reporting in Acute Pancreatitis in A Secondary Care Setting

British Journal of Surgery ◽

10.1093/bjs/znab259.775 ◽

2021 ◽

Vol 108 (Supplement_6) ◽

Author(s):

C Kirchhoff ◽

T J Omokehinde ◽

P Achunine ◽

C Marshall ◽

C Ikechi ◽

...

Keyword(s):

Acute Pancreatitis ◽

Hospital Stay ◽

Ct Scan ◽

Care Setting ◽

Gastrointestinal Disease ◽

Average Length ◽

Length Of Hospital Stay ◽

Abdominal Ultrasound ◽

Computerised Tomography ◽

Secondary Care Setting

Abstract Aim Acute pancreatitis is the world's most common gastrointestinal disease requiring hospital admission. Our audit aim was to assess the timeframe within which Abdominal Ultrasound Scans (USS) and Computerised Tomography (CT) were performed, reported indications for CT and the prognostic factors noted in imaging reports. Method A retrospective search included admissions with acute pancreatitis between 01/09/19 to 30/11/19, collecting demographics, admission time & date, time and date of both radiological investigations and imaging reports. Patients under the age of 18 were excluded. Results This search identified 75 patients (M:F, 40:35) with a median age of 53 (18-95) years. USS were performed within 24 hours of admission in 40.0% (n = 30) of cases. Out of the patients (n = 44) who received a CT scan, 15.9% (n = 7) were scanned after more than 72 hours of onset of symptoms and 84.1% (n = 37) were scanned within less than 72 hours. Furthermore, 88.6%(n = 39) of CT request indications were in keeping with our standards. The average length of hospital stay was 6.1 days when scanned within 72 hours and 11.8 days when scanned after more than 72 hours. Conclusions Only 17.3% (n = 13) of the patients audited met all our standards and were managed according to the guidelines. The average length of hospital stay was half in those who had a CT scan after more than 72 hours of admission and this was also used to monitor disease progression/regression.

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Early Risk Stratification in Acute Pancreatitis: The Role of Biochemical and Hematological Parameters

Internal Medicine ◽

10.2478/inmed-2020-0113 ◽

2020 ◽

Vol 17 (3) ◽

pp. 11-18

Author(s):

Georgiana Cătălina Crișu ◽

Vasile Daniel Balaban ◽

Laura Elena Gaman ◽

Mariana Jinga ◽

Flavius Stefan Marin ◽

...

Keyword(s):

Alkaline Phosphatase ◽

Acute Pancreatitis ◽

Risk Stratification ◽

Hospital Stay ◽

Hematological Parameters ◽

Length Of Hospital Stay ◽

Systemic Complications ◽

Early Risk ◽

Length Of Hospitalization

AbstractAcute pancreatitis (AP) represents an inflammatory condition,-with a wide spectrum of local and systemic complications. Early stratification of severity of pancreatitis is an important step in guiding the management of the disease and improving outcomes. Throughout the years many researchers have looked at various risk stratification parameters which could be used from the admission of patients, however current available scores are cumbersome.Our aim was to evaluate the role of biochemical and hematological parameters in the early stratification of severity of AP, regarding the length of hospitalization.We conducted an observational study which included 100 patients with AP admitted to the Gastroenterology Department over a period 18 months. AP diagnosis was set according to 2013 ACG criteria. Demographic, clinical and imaging data related to the pancreatitis flare were collected from their charts. Length of hospital stay was used as surrogate marker for severity of AP. We evaluated different biochemical and hematological parameters which influenced the length of hospitalization.Several hematological parameters and ratio did not correlate with length of hospital stay in our study cohort, however there was a significant relation of hyperglycemia and alkaline phosphatase levels with hospitalization duration.Early risk stratification in AP remains difficult with routine blood work done at admission. Glycemic control and serum level of alkaline phosphatase seems to be correlated with length of hospital stay.

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