Su1836 - Life Events within the first Year of Life, but not the Neonatal Period Predict the Later Development of IBD: A Population Based Analysis

2018 ◽  
Vol 154 (6) ◽  
pp. S-601
Author(s):  
Charles N. Bernstein ◽  
Charles Burchill ◽  
Laura E. Targownik ◽  
Harminder Singh ◽  
Leslie L. Roos
Epilepsia ◽  
2016 ◽  
Vol 57 (10) ◽  
pp. 1594-1601 ◽  
Author(s):  
Eija Gaily ◽  
Markus Lommi ◽  
Risto Lapatto ◽  
Anna-Elina Lehesjoki

2021 ◽  
pp. 110-113
Author(s):  
Strogiy V.V. ◽  
◽  
Zasim E.V. ◽  
Drozdovsky K.V. ◽  
Kadochkin V.O. ◽  
...  

The goal is to establish the frequency of supraventricular tachycardias in children of the Republic of Belarus, to determine the structure and characteristics of these rhythm disturbances. An in-depth study of the properties of the conduction system of the heart was carried out by performing in the course of the esophageal electrophysiological study 108 children. A more rare detection of SVT in children in the neonatal period, in the first year of life and maximum detection at the age of 17 years, a comparatively rare finding (11.8 %) of concomitant pathology in children with SVT.


Author(s):  
Kate Miller

IntroductionThere is increasing evidence that environmental exposures may be important in the pathogenesis of type 1 diabetes (T1D). Ultraviolet radiation (UVR) is of interest in relation to the development of T1D because of its immunoregulatory actions. Ecological studies testing the correlation between levels of UVR and T1D have shown a significant inverse relationship for both incidence and prevalence. Objectives and Approach We used large linked datasets to test ambient UVR during early life against T1D risk at the individual level. We conducted a nested case-control study using linked data from state-wide administrative datasets and NASA satellites. Cases (n=1819) were all children born in Western Australia from 1980-2014 with a diagnosis of T1D on the population-based Western Australian Children’s Diabetes Database between 0-16 years of age. Controls (n=27 259) were randomly selected from all live births in Western Australia and matched to cases on sex and date of birth. Daily UVR data from NASA satellites, that were date-and location-specific for each individual, were used to estimate total UVR dose for each trimester of pregnancy and the first year of life. ResultsConditional logistic regression showed that T1D risk was 44% lower in boys of mothers with UVR levels in the highest quartile (compared to the lowest quartile) during their third trimester of pregnancy (p=0.04). Higher UVR in the first year of life was also associated with a significantly lower risk of T1D in later childhood among boys. Among girls, there was no evidence of an association between total UVR dose and T1D risk. ConclusionHigher UVR in the third trimester and first year of life appears to interact with sex-specific factors to lower T1D risk among boys (but not girls) in Western Australia.


1982 ◽  
Vol 63 (4) ◽  
pp. 5-7
Author(s):  
E. A. Efimova ◽  
S. L. Nesterov ◽  
N. L. Yashina ◽  
T. K. Shakurova ◽  
V. A. Novikova ◽  
...  

Clinical, cytochemical, and rheological features of the neonatal period were studied in 460 children from mothers suffering from rheumatism or having suffered late toxicosis of pregnant women. On the basis of impaired adaptive reactions, changes in the enzymatic spectrum of blood cells and disorders of microcirculatory mechanisms, children at risk were identified. 50 of them underwent preventive therapy in the neonatal period. The follow-up indicates a lower infectious index during the first year of life in children who received preventive therapy.


2020 ◽  
Vol 56 (5) ◽  
pp. 2000197 ◽  
Author(s):  
Claudio Barbiellini Amidei ◽  
Rosanna Comoretto ◽  
Loris Zanier ◽  
Daniele Donà ◽  
Anna Cantarutti ◽  
...  

Epilepsia ◽  
2007 ◽  
Vol 48 (9) ◽  
pp. 1724-1730 ◽  
Author(s):  
Evald Saemundsen ◽  
Petur Ludvigsson ◽  
Ingibjorg Hilmarsdottir ◽  
Vilhjalmur Rafnsson

2013 ◽  
Vol 45 (01) ◽  
pp. 022-029 ◽  
Author(s):  
Natalie LeCouffe ◽  
Elisabeth Westerbeek ◽  
Petra van Schie ◽  
Veronique Schaaf ◽  
Harrie Lafeber ◽  
...  

1992 ◽  
Vol 29 (5) ◽  
pp. 451-455 ◽  
Author(s):  
Philippe P. Hujoel ◽  
Anne-Marie Bollen ◽  
Beth A. Mueller

Children born with a facial cleft are not thought to be at a greater risk for infant mortality than are those without congenital anomalies. The purpose of this study was to investigate whether the presence of a facial cleft alone or its coexistence with other anomalies increases a child's risk for dying. Birth and death certificate data from Washington State for the years 1984 to 1988 were linked for infants who died before 1 year of age. Mortality rates for different types of facial clefts and for births without noted abnormalities were compared. Relative to infants with no diagnosed abnormalities noted in the birth certificate, infants with facial clefts without other abnormalities have a 3.7 fold increased odds for dying during their first year of life. This elevated risk for dying was fairly consistent during the first year of life. When facial clefts are associated with other abnormalities there is an 82.3 fold increase in odds for mortality during the first year of life. This elevated risk is highest during the neonatal period; 77% of all deaths occurred during the first 27 days. It is concluded that infants with facial clefts with or without associated anomalies have a significantly increased mortality risk when compared to infants without any diagnosed abnormalities at birth.


1963 ◽  
Vol 12 (3) ◽  
pp. 298-307
Author(s):  
Antonino Fiumara

SUMMARYA survey has been made of the birth records of 846 twins (415 pairs and 6 sets of triplets) born in Catania between January 1st, 1959 and May 31st, 1962, with the purpose of establishing the degree of mortality in twins in the first year of life. The results indicate a low degree of still-birth (5%). Identifying the neonatal period with the first week of life, the neonatal mortality is of 8.9%. This percentage undergoes a little reduction (1.9%) when we consider as neonatal period just the first day of life, the twin mortality being lower in the subsequent days of the first week. Except that of the 1st day, the higher frequency of mortality (19%) occurs between the 12th and the 16th day, which is considered a critical period in the first month of life in twins. In the remaining 11 months of the year the mortality degre is low (51 deaths in 680 twins survived to the first month). At the end of the year in 63.1% of the considered pairs both twins were still alive. In six of the 43 pairs with both components dead, both twins died between the 13th and the 25th day, with an interval of 24 hours. The spontaneous death of twin pairs, occurring sometimes simultaneously or with a brief interval in the first month of life, may give rise to judiciary mistakes.


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