Defective control of protein synthesis in colon cancer cells results in constitutive expression of cyclooxygenase-2 protein

1998 ◽  
Vol 114 ◽  
pp. A585
Author(s):  
Dan A. Dixon ◽  
Kelley J. Murphy ◽  
Stephen M. Prescott
Keyword(s):  
Colon Cancer ◽  
Protein Synthesis ◽  
Cancer Cells ◽  
Constitutive Expression ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells

Reduction of intracellular pH inhibits constitutive expression of Cyclooxygenase-2 in human colon cancer cells

2003 ◽  
Vol 198 (2) ◽  
pp. 295-301 ◽  
Author(s):  
Daniela Pirkebner ◽  
Michaela Fuetsch ◽  
Walter Wittmann ◽  
Helmut Weiss ◽  
Thomas Haller ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Intracellular Ph ◽  
Constitutive Expression ◽  
Human Colon ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells

2009 ◽  
Vol 315 (8) ◽  
pp. 1439-1447 ◽  
Author(s):  
Antonio Strillacci ◽  
Cristiana Griffoni ◽  
Pasquale Sansone ◽  
Paola Paterini ◽  
Giulia Piazzi ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Human Colon ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

Somatostatin modulates both cyclooxygenase-2 expression and proliferation in human colon cancer cells

2003 ◽  
Vol 124 (4) ◽  
pp. A100
Author(s):  
Rocchina Colucci ◽  
Corrado Blandizzi ◽  
Marzia Tanini ◽  
Narcisa Ghisu ◽  
Maria Cristina ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Human Colon ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

scholarly journals THE INHIBITION OF POLYISOPRENOIDS FROM NYPA FRUTICANS LEAVES ON CYCLOOXYGENASE 2 EXPRESSION OF WIDR COLON CANCER CELLS

2018 ◽  
Vol 11 (8) ◽  
pp. 154 ◽  
Author(s):  
Dini Permata Sari ◽  
Mohammad Basyuni ◽  
Poppy Anjelisa Zaitun Hasibuan ◽  
Ridha Wati
Keyword(s):  
Colon Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Colon Cancer Cell ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Chemopreventive Agents ◽  
Nypa Fruticans ◽  
Diphenyltetrazolium Bromide ◽  
Cox 2

Objective: The objective of the study was to investigate the inhibitory activity of polyisoprenoids from Nypa fruticans leaves on the expression of cyclooxygenase 2 (COX-2) against colon cancer cells.Methods: Anticancer activity performed was tested by dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method on colon cancer cell WiDr. The expression of COX-2 was observed by the immunocytochemistry method.Result: Polyisoprenoids from N. fruticans leaves exhibit anticancer activity on WiDr cells through inhibition of COX-2 expression with IC50 180.186±7.16 μg/ml.Conclusions: This study showed that polyisoprenoids from N. fruticans leaves promise chemopreventive agents for colon cancer through COX-2 inhibition.

Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells

1999 ◽  
Vol 66 (2) ◽  
pp. 227-233 ◽  
Author(s):  
Kazunori Fukuda ◽  
Yuko Hibiya ◽  
Michihiro Mutoh ◽  
Masatoshi Koshiji ◽  
Seigou Akao ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Transcriptional Activity ◽  
Human Colon ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

An upstream CRE-E-box element is essential for gastrin-dependent activation of the cyclooxygenase-2 gene in human colon cancer cells

2007 ◽  
Vol 144 (1-3) ◽  
pp. 25-33 ◽  
Author(s):  
Nikolaus Ansorge ◽  
Stefan Jüttner ◽  
Thorsten Cramer ◽  
Wolfgang E. Schmidt ◽  
Michael Höcker ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Human Colon ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
E Box ◽  
Human Colon Cancer Cells

DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells

2009 ◽  
Vol 135 (12) ◽  
pp. 1791-1798 ◽  
Author(s):  
Shuang Bing Xu ◽  
Xiao Hong Liu ◽  
Ben Hui Li ◽  
Yan Zhang ◽  
Jia Yuan ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Colon Cancer ◽  
Cancer Cells ◽  
Constitutive Expression ◽  
Regulatory Genes ◽  
Colon Cancer Cells
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