O077 CORRELATION OF BODY MASS INDEX WITH OVARIAN RESERVE IN INFERTILE WOMEN UNDERGOING IVF IN A DEVELOPING COUNTRY

Objective: To evaluate the potential role of vitamin D on ovarian reserve markers in infertile women with different reserve patterns.Study design: This prospective cross-sectional study included the infertile women attending the Hitit University Hospital. The initial examination included the measurements of waist circumference and hip circumference, body mass index, and waist/hip ratio. A total of 171 women were divided into three groups according to ovarian reserve patterns: (i) adequate ovarian reserve pattern (AOR, n=77), (ii) high ovarian reserve pattern (polycystic ovarian syndrome, n=62), and (iii) diminished ovarian reserve pattern (DOR, n=32). The serum estradiol (E2), follicle stimulating hormone, total testosterone, 17-hydroxy-progesterone (17(OH) P), dehydroepiandrosterone sulfate, anti-mullerian hormone, and hydroxycholecalciferol (25(OH) D) levels were analyzed. Results: No significant difference between three different groups was detected in terms of body mass index, waist circumference, hip circumference, waist/hip ratio, E2 and 17OHP levels (p>0.05, for all). One-hundred-sixty-nine (98.2%) women in all groups had vitamin D concentration below 30 ng/mL as a cut-off value. The circulating 25 (OH) D levels did not show a significant difference between all ovarian reserve groups (p=0.804). No correlation between 25(OH) D and anti-mullerian hormone levels was documented in women with AOR, polycystic ovarian syndrome and DOR patterns (r=-0.099 p=0.393, r=0.034 p=0.794 and r=0.157 p=0.390 respectively). 25 (OH) D levels were significantly correlated with body mass index, waist circumference and hip circumference parameters only in AOR group (r=-0.355 p=0.002, r=-0.305 p=0.007 and r=-0.322 p=0.004 respectively).Conclusions: There is no association between 25 (OH) D and ovarian reserve markers. 25 (OH) D levels were significantly correlated with body mass index, waist circumference and hip circumference parameters only in AOR group.

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Correlation of body mass index with outcome of in vitro fertilization in a developing country

Archives of Gynecology and Obstetrics ◽

10.1007/s00404-011-2013-8 ◽

2011 ◽

Vol 285 (1) ◽

pp. 259-263 ◽

Cited By ~ 15

Author(s):

Neeta Singh ◽

Prerna Gupta ◽

Suneeta Mittal ◽

Neena Malhotra

Keyword(s):

Body Mass Index ◽

In Vitro Fertilization ◽

Developing Country ◽

Body Mass ◽

Vitro Fertilization

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Prevalence of dysglycemia and its associations with age and body mass index among community dwelling adults in a developing country

International Journal of Diabetes in Developing Countries ◽

10.1007/s13410-021-00995-9 ◽

2021 ◽

Author(s):

Keddagoda Gamage Piyumi Wasana ◽

Anoja Priyadarshani Attanayake ◽

Thilak Priyantha Weerarathna ◽

Kamani Ayoma Perera Wijewardana Jayatilaka

Keyword(s):

Body Mass Index ◽

Developing Country ◽

Body Mass ◽

Community Dwelling

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Insulin resistance in relation to clinical, endocrine and metabolic profile of infertile women with polycystic ovary syndrome

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v14i1.50989 ◽

2021 ◽

Vol 14 (1) ◽

pp. 1-6

Author(s):

Shakeela Ishrat ◽

Marufa Hossain ◽

Subrata Kumar Biswas

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Body Mass Index ◽

Waist Circumference ◽

Polycystic Ovary Syndrome ◽

Body Mass ◽

Polycystic Ovary ◽

Ovary Syndrome ◽

Infertile Women ◽

Significant Difference

The objective of this study is to explore how hyperinsulinemia and insulin resistance relate to the clinical, endocrine and metabolic factors in the infertile women with polycystic ovary syndrome. This study was conducted on 121 consecutive infertile women with polycystic ovary syndrome attending the Infertility unit from January 2017 to December 2017. They were divided into two groups: insulin resistant and insulin sensitive. There was significant difference in body mass index and waist circumference between the two groups. Serum lipids were not associated with insulin resistance. Hyperinsulinemia was significantly associated with metabolic syndrome. Reducing body mass index and waist circumference may improve insulin resistance in infertile women with polycystic ovary syndrome. Screening the infertile women with polycystic ovary syndrome for hyperinsulinemia and insulin resistance and subsequent counseling is recommended to address the long-term risks of metabolic syndrome.

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Impact of body mass index on the correlation of follicle stimulating hormone and antral follicle count with anti-mullerian hormone to measure ovarian reserve

Fertility and Sterility ◽

10.1016/j.fertnstert.2013.07.1524 ◽

2013 ◽

Vol 100 (3) ◽

pp. S160-S161

Author(s):

D.D. Gunn ◽

M.R. McLean ◽

R.L. Griffin ◽

J.F. McLaren

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Ovarian Reserve ◽

Follicle Stimulating Hormone ◽

Antral Follicle ◽

Antral Follicle Count ◽

Stimulating Hormone

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The Influence of Depression, Body Mass Index, and Smoking on Serum Inhibin B Levels in Late Reproductive-Aged Women

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2005-2515 ◽

2006 ◽

Vol 91 (4) ◽

pp. 1496-1500 ◽

Cited By ~ 20

Author(s):

G. M. Lambert-Messerlian ◽

B. L. Harlow

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Ovarian Reserve ◽

Psychosocial Functioning ◽

Reproductive Function ◽

Inhibin B ◽

Smoking History ◽

Serum Samples ◽

History Of ◽

History Of Depression

Context: Women experiencing depression have difficult psychosocial functioning, and recent data suggest an earlier onset of menopause. Understanding the biological mechanism for the impairment of reproductive function associated with depression is important. Objective: The objective of the study was to determine whether a lifetime history of depression is associated with reduced ovarian reserve as reflected in serum levels of the granulosa cell product, inhibin B. Design: Residual serum samples from a subset of patients in the Harvard Study of Cycles and Moods were collected. Setting: Patients were recruited from seven Boston-area communities. Patients: Women with or without a history of major depression, based on structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were enrolled. A subset of patients who had provided an early follicular phase blood specimen at study enrollment and two or more other samples over the first 18-month period of follow-up were included. Intervention: There were no interventions. Main Outcome Measure: Serum inhibin B levels were measured. Results: Serum FSH levels were higher in women with a history of depression, whereas inhibin B levels did not differ between groups. Body mass index and age were significantly and inversely related to serum inhibin B levels. Smoking history was noted, for the first time, to have a significant negative association with inhibin B levels. Conclusions: Smoking has a direct negative effect on ovarian reserve, as suggested by decreased serum inhibin B levels. In contrast, effects of depression on the reproductive axis may occur at the level of the pituitary and/or hypothalamus rather than at the gonadal level, as suggested by increased serum FSH levels.

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