High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nationwide survey

Background: Several components of the Metabolic Syndrome (MetS) are risk factor for cardiovascular diseases. So, this study was conducted to evaluate the prevalence of MetS and its components in patients with CAD.Methods: Author included all patients admitted with Acute Coronary Syndrome (ACS), who had CAD confirmed by coronary angiography. They were divided into two groups according to presence or absence of MetS based on International Diabetes Federation criteria. The prevalence of MetS and its individual components was estimated.Results: It was observed that there is a high prevalence of MetS (66%) in patients admitted with ACS. Metabolic syndrome is more prevalent in female patients (82.4%) than in male patients (57.6%) with ACS. Hypertension is the most prevalent (87.9) component of MetS. Diabetes Mellitus (DM) is the 2nd most prevalent (83.3%) component of MetS. About 65.2% patients with MetS had abnormally raised triglyceride levels and 32(48.5%) had abnormally low HDL-cholesterol level. Among the MetS 38(57.6%) had abnormal waist circumference. Among the study group, the most common triad of MetS components was DM + HTN + abnormal TG. There is significant association between MetS and microalbuminuria, with incidence of 22(33.3%) in this study. Similarly, a significant association between DM and microalbuminuria, 23(33.8%) was observed.Conclusions: This study confirms a very high prevalence of MetS in Indian patients with CAD. The prevalence of the risk factors was higher in CAD patients with MetS.

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ERICA: prevalence of dyslipidemia in Brazilian adolescents

Revista de Saúde Pública ◽

10.1590/s01518-8787.2016050006723 ◽

2016 ◽

Vol 50 (suppl 1) ◽

Cited By ~ 13

Author(s):

José Rocha Faria Neto ◽

Vivian Freitas Rezende Bento ◽

Cristina Pellegrino Baena ◽

Marcia Olandoski ◽

Luis Gonzaga de Oliveira Gonçalves ◽

...

Keyword(s):

Total Cholesterol ◽

Ldl Cholesterol ◽

Plasma Lipids ◽

Significant Proportion ◽

Hdl Cholesterol ◽

Cross Sectional Study ◽

Cardiovascular Risks ◽

Cross Sectional ◽

High Prevalence ◽

Low Hdl

ABSTRACT OBJECTIVE To determine the distribution of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides in Brazilian adolescents, as well as the prevalence of altered levels of such parameters. METHODS Data from the Study of Cardiovascular Risks in Adolescents (ERICA) were used. This is a country-wide, school-based cross-sectional study that evaluated 12 to 17-year old adolescents living in cities with over 100,000 inhabitants. The average and distribution of plasma levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides were evaluated. Dyslipidemia was determined by levels of total cholesterol ≥ 170 mg/dl, LDL cholesterol ≥ 130 mg/dl, HDL cholesterol < 45 mg/dL, or triglycerides ≥ 130 mg/dl. The data were analyzed by gender, age, and regions in Brazil. RESULTS We evaluated 38,069 adolescents – 59.9% of females, and 54.2% between 15 and 17 years. The average values found were: total cholesterol = 148.1 mg/dl (95%CI 147.1-149.1), HDL cholesterol = 47.3 mg/dl (95%CI 46.7-47.9), LDL cholesterol = 85.3 mg/dl (95%CI 84.5-86.1), and triglycerides = 77.8 mg/dl (95%CI 76.5-79.2). The female adolescents had higher average levels of total cholesterol, LDL cholesterol, and HDL cholesterol, without differences in the levels of triglycerides. We did not observe any significant differences between the average values among 12 to 14 and 15- to 17-year old adolescents. The most prevalent lipid alterations were low HDL cholesterol (46.8% [95%CI 44.8-48.9]), hypercholesterolemia (20.1% [95%CI 19.0-21.3]), and hypertriglyceridemia (7.8% [95%CI 7.1-8.6]). High LDL cholesterol was found in 3.5% (95%CI 3.2-4.0) of the adolescents. Prevalence of low HDL cholesterol was higher in Brazil’s North and Northeast regions. CONCLUSIONS A significant proportion of Brazilian adolescents has alterations in their plasma lipids. The high prevalence of low HDL cholesterol and hypertriglyceridemia, especially in Brazil’s North and Northeast regions, must be analyzed in future studies, to support the creation of strategies for efficient interventions.

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Is a high prevalence of low HDL-cholesterol the key to high cardiovascular mortality in females of New-foundland?

Atherosclerosis ◽

10.1016/0021-9150(94)93096-1 ◽

1994 ◽

Vol 109 (1-2) ◽

pp. 21

Author(s):

R. Cifkova ◽

J.G. Fodor ◽

A. Chockalingam ◽

T. Riman ◽

G. Gondos ◽

...

Keyword(s):

Cardiovascular Mortality ◽

Hdl Cholesterol ◽

High Prevalence ◽

Low Hdl

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Prominent role of low HDL-cholesterol in explaining the high prevalence of the metabolic syndrome in polycystic ovary syndrome

Nutrition Metabolism and Cardiovascular Diseases ◽

10.1016/j.numecd.2009.01.007 ◽

2009 ◽

Vol 19 (11) ◽

pp. 797-804 ◽

Cited By ~ 28

Author(s):

A. Gambineri ◽

A. Repaci ◽

L. Patton ◽

I. Grassi ◽

P. Pocognoli ◽

...

Keyword(s):

Metabolic Syndrome ◽

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Hdl Cholesterol ◽

Ovary Syndrome ◽

The Metabolic Syndrome ◽

High Prevalence ◽

Low Hdl

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High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in the Netherlands: Identification and characterization of eight novel mutations

Human Mutation ◽

10.1002/humu.21578 ◽

2011 ◽

Vol 32 (11) ◽

pp. 1290-1298 ◽

Cited By ~ 26

Author(s):

Adriaan G. Holleboom ◽

Jan A. Kuivenhoven ◽

Frank Peelman ◽

Alinda W. Schimmel ◽

Jorge Peter ◽

...

Keyword(s):

The Netherlands ◽

Hdl Cholesterol ◽

Novel Mutations ◽

Cholesterol Levels ◽

High Prevalence ◽

Low Hdl ◽

Identification And Characterization

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Tu1497 NATIONWIDE SURVEY OF HELICOBACTER PYLORI ANTIBIOTIC RESISTANCE IN HIGH PREVALENCE OF GASTRIC CANCER COUNTRY (BHUTAN): A LARGE-SCALE COMMUNITY-BASED STUDY

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2020.03.3669 ◽

2020 ◽

Vol 91 (6) ◽

pp. AB591-AB592

Author(s):

Ratha-Korn Vilaichone ◽

Natsuda Aumpan ◽

Tomohisa Uchida ◽

Thawee Ratanachu-ek ◽

Lotay Tshering ◽

...

Keyword(s):

Gastric Cancer ◽

Helicobacter Pylori ◽

Antibiotic Resistance ◽

Large Scale ◽

Nationwide Survey ◽

Community Based ◽

High Prevalence

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Adherence to treatment in paediatric patients – results of the nationwide survey in Poland

BMC Pediatrics ◽

10.1186/s12887-020-02477-z ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Przemyslaw Kardas ◽

Marek Dabrowa ◽

Konrad Witkowski

Keyword(s):

Professional Practice ◽

Patient Adherence ◽

Nationwide Survey ◽

Full Potential ◽

Strongly Correlated ◽

Adherence To Treatment ◽

Cross Sectional ◽

Convenience Sample ◽

Paediatric Patients ◽

High Prevalence

Abstract Background Due to high prevalence, non-adherence to prescribed treatment seriously undermines the effectiveness of evidence-based therapies in paediatric patients. In order to change this negative scenario, physicians need to be aware of adherence problem, as well as of possible solutions. Unfortunately, full potential of adherence-targeting interventions is still underused in Poland. Therefore, the aim of this study was to assess the knowledge, attitudes and behaviours toward non-adherence in Polish paediatricians. Methods An anonymous cross-sectional nationwide survey was conducted in the convenience sample of Polish doctors providing care to paediatric patients. The survey focused on the prevalence of non-adherence, its causes, and interventions employed. Primary studied parameter was perceived prevalence of non-adherence in paediatric patients. Reporting of this study adheres to STROBE guidelines. Results One thousand and thirty-three responses were eligible for analysis. Vast majority of respondents were female (85.9%), most of them worked in primary care (90.6%). The respondents represented all 16 Polish Voivodeships, with the biggest number coming from the Mazowieckie Voivodeship (n = 144, 13.9%). Survey participants believed that on average 28.9% of paediatric patients were non-adherent to medication. More than half of the respondents (n = 548, 53.0%) were convinced that their own patients were more adherent than average. Duration of the professional practice strongly correlated with a lower perceived prevalence of non-adherence. Professionals with more than 40 years of practice believed that the percentage of non-adherent patients was <=20% particularly often (OR = 3.82 (95% CI 2.11–6.93) versus those up to 10 years in practice). Out of all respondents, they were also most often convinced that their own patients were more adherent than the general population (P < 0.01). Consequently, they underestimated the need for training in this area. Conclusions Physicians taking care of Polish paediatric patients underestimated the prevalence of medication non-adherence and believed that this was a problem of other doctors. This optimistic bias was particularly pronounced in older doctors. These results identify important barriers toward improving patient adherence that are worth addressing in the pre- and post-graduate education of Polish physicians. They also put some light over the challenges that educational activities in this area may face.

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