Relationships between fasting plasma insulin, anthropometrics, and metabolic parameters in a very old healthy population

Metabolism ◽  
1998 ◽  
Vol 47 (5) ◽  
pp. 535-540 ◽  
Author(s):  
M. Carantoni ◽  
G. Zuliani ◽  
S. Volpato ◽  
E. Palmieri ◽  
A. Mezzetti ◽  
...  
Keyword(s):  
Plasma Insulin ◽  
Metabolic Parameters ◽  
Healthy Population ◽  
Very Old ◽  
Fasting Plasma ◽  
Fasting Plasma Insulin

Increased Fasting Plasma Insulin Concentrations are Associated with the Severity of Angiographic Coronary Artery Disease

Angiology ◽  
2005 ◽  
Vol 56 (3) ◽  
pp. 249-251 ◽  
Author(s):  
Rishi Sukhija ◽  
Wilbert S. Aronow ◽  
Devraj Nayak ◽  
Chul Ahn ◽  
Melvin B. Weiss
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Plasma Insulin ◽  
Fasting Plasma ◽  
Fasting Plasma Insulin ◽  
Artery Disease

Effect of insulin on uric acid excretion in humans

1995 ◽  
Vol 268 (1) ◽  
pp. E1-E5 ◽  
Author(s):  
A. Quinones Galvan ◽  
A. Natali ◽  
S. Baldi ◽  
S. Frascerra ◽  
G. Sanna ◽  
...  
Keyword(s):  
Uric Acid ◽  
Plasma Insulin ◽  
Excretion Rate ◽  
Fractional Excretion ◽  
Urine Flow ◽  
Insulin Resistant ◽  
Fasting Plasma ◽  
Frequent Finding ◽  
Fasting Plasma Insulin ◽  
Induced Changes

Although hyperuricemia is a frequent finding in insulin-resistant states, insulin's effect on renal uric acid (UA) handling is not known. In 20 healthy volunteers, diastolic blood pressure, body weight, and fasting plasma insulin were positively (and age was negatively) related to fasting plasma UA concentrations, together accounting for 53% of their variability. During an insulin clamp, urine flow was lower than during fasting conditions (1.01 +/- 0.12 vs. 1.56 +/- 0.32 ml/min, P = 0.04), whereas creatinine clearance was unchanged (129 +/- 7 and 131 +/- 9 ml/min, P = not significant). Hyperinsulinemia did not alter serum UA concentrations (303 +/- 13 vs. 304 +/- 12 microM) but caused a significant decrease in urinary UA excretion [whether expressed as absolute excretion rate (1.66 +/- 0.21 vs. 2.12 +/- 0.23 mumol/min, P = 0.03), clearance rate (5.6 +/- 0.8 vs. 7.3 +/- 0.8 ml/min, P = 0.03), or fractional excretion (4.48 +/- 0.80 ml/min vs. 6.06 +/- 0.64%, P < 0.03)]. Hyperinsulinemia was also associated with a 30% (P < 0.001) fall in urine Na excretion. Fractional UA excretion was related to Na fractional excretion under basal conditions (r = 0.59, P < 0.01) and during the insulin period (r = 0.53, P < 0.02). Furthermore, the insulin-induced changes in fractional UA and Na excretion correlated with one another (r = 0.66, P < 0.001). Physiological hyperinsulinemia acutely reduces urinary UA and Na excretion in a coupled fashion.

scholarly journals Fasting Plasma Insulin at 5 Years of Age Predicted Subsequent Weight Increase in Early Childhood over a 5-Year Period—The Da Qing Children Cohort Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0127389 ◽  
Author(s):  
Yan Yan Chen ◽  
Jin Ping Wang ◽  
Ya Yun Jiang ◽  
Hui Li ◽  
Ying Hua Hu ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cohort Study ◽  
Plasma Insulin ◽  
Weight Increase ◽  
Fasting Plasma ◽  
Fasting Plasma Insulin
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