A Study of the Immunological Relationship of Anaplasma Marginale and Anaplasma Centrale

1967 ◽  
Vol 8 (4) ◽  
pp. 467-471 ◽  
Author(s):  
K.L. Kuttler
Keyword(s):  
Anaplasma Marginale ◽  
Immunological Relationship ◽  
Relationship Of ◽  
Anaplasma Centrale

scholarly journals Immunological Relationship of Different Preparations of Coliform Enterotoxins

1978 ◽  
Vol 21 (3) ◽  
pp. 771-778 ◽  
Author(s):  
Frederick A. Klipstein ◽  
Richard F. Engert
Keyword(s):  
Immunological Relationship ◽  
Relationship Of

The Dexamethasone-Induced Inhibitor of Plasminogen Activator in Hepatoma Cells Is Antigenically-Related to an Inhibitor Produced by Bovine Aortic Endothelial Cells

1986 ◽  
Vol 55 (01) ◽  
pp. 008-011 ◽  
Author(s):  
David J Loskutoff ◽  
Karen Roegner ◽  
Larry A Erickson ◽  
Raymond R Schleef ◽  
Anna Huttenlocher ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Plasminogen Activator ◽  
Specific Inhibitor ◽  
Hepatoma Cells ◽  
Biochemical Properties ◽  
Aortic Endothelial Cells ◽  
Bovine Aortic Endothelial Cells ◽  
Immunological Relationship ◽  
Relationship Of ◽  
Aortic Endothelial

SummaryGlucocorticoids decrease plasminogen activator (PA) activity in HTC rat hepatoma cells by inducing a specific inhibitor of PA activity (PAI). This inhibitor is similar in several biochemical properties to the PAI purified from bovine aortic endothelial cells (BAEs). We have used reverse fibrin autography and antiserum against BAE PAI to establish more fully the biochemical and immunological relationship of these inhibitors. Both inhibitors migrated with an apparent Mr of approximately 50,000, and the activity of both PAIs was stimulated by treatment with SDS suggesting that each of these molecules exists in both an active and a latent form. Antiserum to the BAE PAI immunoprecipi-tated all of the HTC PAI demonstrable by reverse fibrin autography. Finally, using this antiserum in a functional immunoassay, we have demonstrated that dexamethasone increases both active and latent PAI made by HTC cells. These results, indicate that HTC PAI and BAE PAI are antigenically as well as biochemically related molecules.

Immunological studies of the uncoupling protein of brown adipose tissue

1985 ◽  
Vol 63 (2) ◽  
pp. 96-101 ◽  
Author(s):  
Michael Afong ◽  
Kimberley A. Olynyk ◽  
Hasmukh V. Patel ◽  
John Arnold ◽  
Shuen-Kuei Liao ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Uncoupling Protein ◽  
Mammalian Species ◽  
Cross Reactivity ◽  
Rabbit Antibody ◽  
Antibody Preparation ◽  
Brown Adipose ◽  
Immunological Relationship ◽  
Relationship Of

The immunological relationship of the uncoupling protein from brown adipose tissue of several mammalian species was examined by using a rabbit antibody preparation against the rat protein. Complete cross-reactivity of the antibody to the protein from hamster, mouse, and rat was found, whereas the protein from rabbit cross-reacted only 25%. Cross-reactivity was also found with the human uncoupling protein, although the human protein was found to be about 1 kdalton smaller than the rat protein. No protein of the size of the uncoupling protein was detected in several tumor cell lines examined.

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