[29] In vitro modeling of biofouling of dental composite materials

This in vitro study analyses the biochemical interaction between saliva and three types of dental composite resins (a direct resin, an indirect resin and a dual-cure resin used for cementation of indirect dental restorations). The resin samples were obtained following a specific protocol and in line with the producers� recommendations; the resin samples were incubated with saliva samples collected from 19 healthy volunteers. The obtained results showed that the tested composite resins did not produce significant changes in oxidative stress parameters that were analysed (albumin, uric acid, GGT / gamma glutamyl transferase, OXSR-1 / oxidative stress responsive kinase 1) and do not influence the inflammatory salivary status reflected by the levels of IL-6 - an inflammatory marker.

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The Photoinitiators Used in Resin Based Dental Composite—A Review and Future Perspectives

Polymers ◽

10.3390/polym13030470 ◽

2021 ◽

Vol 13 (3) ◽

pp. 470

Author(s):

Andrea Kowalska ◽

Jerzy Sokolowski ◽

Kinga Bociong

Keyword(s):

Current Knowledge ◽

Biomechanical Properties ◽

Degree Of Conversion ◽

Dental Composite ◽

Polymerization Process ◽

Dental Composites ◽

Dental Resin ◽

Dental Resins ◽

Light Curing

The presented paper concerns current knowledge of commercial and alternative photoinitiator systems used in dentistry. It discusses alternative and commercial photoinitiators and focuses on mechanisms of polymerization process, in vitro measurement methods and factors influencing the degree of conversion and hardness of dental resins. PubMed, Academia.edu, Google Scholar, Elsevier, ResearchGate and Mendeley, analysis from 1985 to 2020 were searched electronically with appropriate keywords. Over 60 articles were chosen based on relevance to this review. Dental light-cured composites are the most common filling used in dentistry, but every photoinitiator system requires proper light-curing system with suitable spectrum of light. Alternation of photoinitiator might cause changing the values of biomechanical properties such as: degree of conversion, hardness, biocompatibility. This review contains comparison of biomechanical properties of dental composites including different photosensitizers among other: camphorquinone, phenanthrenequinone, benzophenone and 1-phenyl-1,2 propanedione, trimethylbenzoyl-diphenylphosphine oxide, benzoyl peroxide. The major aim of this article was to point out alternative photoinitiators which would compensate the disadvantages of camphorquinone such as: yellow staining or poor biocompatibility and also would have mechanical properties as satisfactory as camphorquinone. Research showed there is not an adequate photoinitiator which can be as sufficient as camphorquinone (CQ), but alternative photosensitizers like: benzoyl germanium or novel acylphosphine oxide photoinitiators used synergistically with CQ are able to improve aesthetic properties and degree of conversion of dental resin.

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In vitro modeling of the interaction between human epithelial cells and lymphocytes upon influenza infection

Influenza and Other Respiratory Viruses ◽

10.1111/irv.12394 ◽

2016 ◽

Vol 10 (5) ◽

pp. 438-442 ◽

Cited By ~ 1

Author(s):

Natalia A. Ilyushina ◽

Peter F. Wright

Keyword(s):

Epithelial Cells ◽

Influenza Infection ◽

In Vitro Modeling ◽

Human Epithelial Cells

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In vitro modeling of the structure–activity determinants of anthracycline cardiotoxicity

Cell Biology and Toxicology ◽

10.1007/s10565-006-0143-8 ◽

2006 ◽

Vol 23 (1) ◽

pp. 49-62 ◽

Cited By ~ 32

Author(s):

P. Menna ◽

G. Minotti ◽

E. Salvatorelli

Keyword(s):

Anthracycline Cardiotoxicity ◽

In Vitro Modeling ◽

Structure Activity

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Lessons from patient-derived xenografts for better in vitro modeling of human cancer

Advanced Drug Delivery Reviews ◽

10.1016/j.addr.2014.09.009 ◽

2014 ◽

Vol 79-80 ◽

pp. 222-237 ◽

Cited By ~ 98

Author(s):

Stephen Yiu Chuen Choi ◽

Dong Lin ◽

Peter W. Gout ◽

Colin C. Collins ◽

Yong Xu ◽

...

Keyword(s):

Human Cancer ◽

In Vitro Modeling

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Materiais Promissores para Melhorar as Propriedades Mecânicas e Físico-Químicas do Cimento de Ionômero de Vidro

Journal of Health Sciences ◽

10.17921/2447-8938.2017v19n5p104 ◽

2018 ◽

Vol 19 (5) ◽

pp. 104 ◽

Cited By ~ 1

Author(s):

M R R Silva ◽

N J C Sena ◽

D A Cunha ◽

L C Souza ◽

N S Rodrigues ◽

...

Keyword(s):

Dental Materials ◽

Dental Composite ◽

Glass Ionomer Cements ◽

Glass Ionomer

O objetivo deste trabalho é realizar uma revisão de literatura sobre os materiais que estão sendo associados ao cimento de ionômero de vidro (CIV), visando melhorar suas propriedades mecânicas e físico-químicas. Foi realizada uma seleção de artigos científicos nas bases de dados PubMed, Europe PMC e ScienceDirect, usando os descritores Glass Ionomer Cements, Dental Materials e Dental Composite. O critério de inclusão foi estudo in vitro acerca do tema proposto e os de exclusão foram revisões de literatura e estudos clínicos. Foram encontrados 130 artigos, publicados entre os anos de 2012 a 2017, dos quais foram selecionados 10. De acordo com esta revisão, o uso de substâncias naturais, tais como os nanocristais de celulose, melhorou a resistência à compressão e diametral, módulo de elasticidade e resistência ao desgaste do CIV. Já a associação com o propólis resultou na diminuição significativa da resistência à compressão e o aumento da solubilidade do CIV. O uso das nanopartículas de AlO, ZrO e TiO2 foi avaliado, mostrando redução da porosidade dos cimentos ionoméricos e aumento da resistência à compressão. Quando o Nanoclay (montmorillonita de grau polimérico) foi adicionado à porção líquida do CIV, suas propriedades mecânicas melhoraram, entretanto a resistência à tensão diametral não apresentou melhora estatística significante. Portanto, o uso de substâncias associadas ao CIV mostrou melhora de suas propriedades, principalmente quando os nanocristais de celulose foram utilizados, podendo representar um novo e promissor material de restauração dentária.Palavras-chave: Cimentos de Ionômeros de Vidro. Materiais Dentários. Propriedades Físicas e Químicas.

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The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model BisGMA/TEGDMA dental composite initially and after aging

Metallurgical and Materials Engineering ◽

10.30544/403 ◽

2018 ◽

Vol 24 (4) ◽

Cited By ~ 2

Author(s):

Tamara Matic ◽

Maja Ležaja Zebić ◽

Ivana Cvijović-Alagić ◽

Vesna Miletić ◽

Rada Petrović ◽

...

Keyword(s):

Mechanical Properties ◽

Body Fluid ◽

Control Sample ◽

Dental Composite ◽

In Vitro Bioactivity ◽

Significant Difference ◽

Nanosized Hydroxyapatite ◽

Glass Fillers ◽

Mg Doped

The aim of this study was to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p>0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected. Keywords: hydroxyapatite; magnesium; dental composite; mechanical properties;

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