Hydrogels based on poly(ethylene oxide) and poly(tetramethylene oxide) or poly(dimethyl siloxane): synthesis, characterization, in vitro protein adsorption and platelet adhesion

Biomaterials ◽  
2002 ◽  
Vol 23 (8) ◽  
pp. 1797-1808 ◽  
Author(s):  
Jae Hyung Park ◽  
You Han Bae
Keyword(s):  
Ethylene Oxide ◽  
Protein Adsorption ◽  
Platelet Adhesion ◽  
Dimethyl Siloxane ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Vitro Protein ◽  
Tetramethylene Oxide

Poly(ethylene oxide) Grafted to Silicon Surfaces: Grafting Density and Protein Adsorption

1998 ◽  
Vol 31 (15) ◽  
pp. 5059-5070 ◽  
Author(s):  
Susan J. Sofia ◽  
V. Premnath ◽  
Edward W. Merrill
Keyword(s):  
Ethylene Oxide ◽  
Protein Adsorption ◽  
Silicon Surfaces ◽  
Grafting Density ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Surface Modification of Copolyether-Urethane Catheters with Poly(Ethylene Oxide)

1989 ◽  
Vol 12 (6) ◽  
pp. 390-394 ◽  
Author(s):  
E. Brinkman ◽  
A. Poot ◽  
T. Beugeling ◽  
L. Van Der Does ◽  
A. Bantjes
Keyword(s):  
Surface Modification ◽  
Ethylene Oxide ◽  
Blood Compatibility ◽  
Angle Measurements ◽  
Fold Reduction ◽  
Contact Angle Measurements ◽  
Platelet Deposition ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Pellethane 2363 80A catheters were modified with poly(ethylene oxide) in order to improve their blood compatibility. Contact angle measurements showed that Pellethane 2363 80A surfaces had increased wettability after this modification. The results of in vitro blood compatibility tests showed that surface modification with poly(ethylene oxide) resulted in a five-fold reduction of platelet deposition. Activation of coagulation was not affected.

Fabrication of electrospun poly(ethylene oxide)–poly(capro lactone) composite nanofibers for co-delivery of niclosamide and silver nanoparticles exhibits enhanced anti-cancer effects in vitro

2016 ◽  
Vol 4 (4) ◽  
pp. 726-742 ◽  
Author(s):  
Poornima Dubey ◽  
P. Gopinath
Keyword(s):  
Silver Nanoparticles ◽  
Ethylene Oxide ◽  
Anticancer Drugs ◽  
Composite Nanofibers ◽  
Water Solubility ◽  
Intrinsic Property ◽  
Anti Cancer ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

An intrinsic property of many anticancer drugs including niclosamide is poor water solubility, which hindered their translation from laboratory to clinics.

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