SUN-PP124: Correlation between Mini Nutritional Assessment and Hand Grip Strength in Geriatric Patients with Gastrointestinal Cancer

2015 ◽  
Vol 34 ◽  
pp. S69
Author(s):  
D. Hopanci Bicakli ◽  
A. Ozveren ◽  
B. Karabulut ◽  
R. Uslu ◽  
R.M. Dalak ◽  
...  
Keyword(s):  
Grip Strength ◽  
Gastrointestinal Cancer ◽  
Geriatric Patients ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
Hand Grip Strength ◽  
Hand Grip

Hand-grip strength does not correlate with treatment-related weight loss in patients with head and neck cancer

2015 ◽  
Vol 129 (7) ◽  
pp. 706-709 ◽  
Author(s):  
B Cosway ◽  
M Easby ◽  
S Covington ◽  
I Bowe ◽  
V Paleri
Keyword(s):  
Head And Neck Cancer ◽  
Nutritional Status ◽  
Head And Neck ◽  
Grip Strength ◽  
Neck Cancer ◽  
Nutritional Assessment ◽  
Hand Grip Strength ◽  
Prospective Audit ◽  
Hand Grip ◽  
Routine Assessment

AbstractBackground:Hand-grip strength has been shown to be a reliable predictor of health outcomes. However, evidence supporting its use as an indicator of nutritional status is inconsistent. This study investigated its use in monitoring nutritional status in patients with head and neck cancer.Methods:A prospective audit of patients treated for head and neck cancer was undertaken at four centres over a three-month period in 2009. Nutritional outcomes were collected at 3, 6 and 12 months, and the data were statistically analysed.Results:Data from 114 patients showed that mean weight, but not hand-grip strength, fell significantly at 3, 6 and 12 months post-treatment (p < 0.003 vs p < 0.126).Conclusion:A fall in weight does not coincide with a drop in hand-grip strength in patients receiving treatment for head and neck cancer. Hand-grip strength may therefore not be of benefit in the nutritional assessment of these patients and should not be part of routine assessment.

IGF-I/IGFBP3/ALS deficiency in sarcopenia: low GHBP suggests GH resistance in a subgroup of geriatric patients

2020 ◽  
Author(s):  
Uta Ferrari ◽  
Ralf Schmidmaier ◽  
Theresa Jung ◽  
Martin Reincke ◽  
Sebastian Martini ◽  
...  
Keyword(s):  
Grip Strength ◽  
Geriatric Patients ◽  
Binding Protein ◽  
Hand Grip Strength ◽  
Statistical Regression ◽  
Cross Sectional ◽  
Skeletal Muscle Index ◽  
Hand Grip ◽  
Igf I ◽  
Gh Resistance

Abstract Context Definition of etiological subgroups of sarcopenia may help to develop targeted treatments. Insulin like growth factor (IGF-I), IGF-binding protein 3 (IGFBP3) and acid labile subunit (ALS) build a ternary complex that mediates growth hormone (GH) effects on peripheral organs, such as muscle. Low GH binding protein (GHBP) as a marker of GH receptor number would hint towards GH resistance. Objective Analysis of the association of IGF-I, IGFBP3, and ALS with sarcopenia Study Participants and setting 131 consecutively recruited patients of a geriatric ward for a mono-center cross-sectional analysis, non-sarcopenic patients served as controls. Methods Sarcopenia status by hand grip strength measurement and Skeletal Muscle Index (SMI); IGF-I, IGFBP3, ALS, GH, GH binding protein (GHBP); body mass index (BMI), Activity of Daily Living (ADL), mini mental state test (MMST), routine laboratory parameters, statistical regression modelling. Results Compared to controls, sarcopenic patients did not differ regarding age, sex, ADL, MMST, C reactive protein, glomerular filtration rate and albumin serum concentrations. However, sarcopenic patients had significantly lower IGF-I, IGFBP3 and ALS. IGF I and ALS associated significantly with sarcopenia and low hand grip strength, even after adjustment for age, sex, BMI and albumin, but not with low SMI. GHBP serum was low in sarcopenic patients, but normal in geriatric patients without sarcopenia. Over 60% of patients with IGF-I/ALS deficiency patients showed GH resistance. Conclusions Our data suggest that in geriatric patients low IGF-I/IGFBP3/ALS could be evaluated for causative connection of the sarcopenia spectrum. Low GHBP points towards potential GH resistance as one possible explanation of this deficiency.

scholarly journals HAND GRIP STRENGTH AS A NUTRITIONAL ASSESSMENT TOOL IN PATIENTS WITH LIVER CIRRHOSIS.

2016 ◽  
Vol 4 (11) ◽  
pp. 1183-1191
Author(s):  
Shaimaa Elkholy ◽  
◽  
Sherif Mogawer ◽  
Mona Mansour ◽  
Reem Elmessiery ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Grip Strength ◽  
Assessment Tool ◽  
Nutritional Assessment ◽  
Hand Grip Strength ◽  
Hand Grip

SAT-084-Validation of hand grip strength as a nutritional assessment tool for patients with advanced liver fibrosis

2019 ◽  
Vol 70 (1) ◽  
pp. e665
Author(s):  
Topan Mirabela-Madalina ◽  
Mirela Danila ◽  
Roxana Sirli ◽  
ana-maria ghiuchici ◽  
calin burciu ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Grip Strength ◽  
Assessment Tool ◽  
Nutritional Assessment ◽  
Hand Grip Strength ◽  
Hand Grip ◽  
Advanced Liver Fibrosis

scholarly journals Hand Grip Strength as a Predictor of Postoperative Complications Following Resection in Patients with Primary Liver Cancer: A Retrospective Cohort study

2020 ◽  
Author(s):  
Chunlei Li ◽  
Hongmei Wu ◽  
Yaqi Zeng ◽  
Jie Dong ◽  
Yajun Chen ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Liver Cancer ◽  
Grip Strength ◽  
Nutritional Assessment ◽  
Primary Liver Cancer ◽  
Incidence Rates ◽  
Hand Grip Strength ◽  
Assessment Tools ◽  
University Hospital ◽  
Hand Grip

Abstract Background: The incidence of complications after hepatectomy for primary liver cancer (PLC) remains high. In this regard, a rapid, simple and inexpensive method is needed to assess the nutritional status of patients before surgery. This study aimed to determine the predictive value of hand grip strength (HGS) for postoperative complications of PLC. Methods: This retrospective study was conducted at a university hospital. A total of 147 patients with PLC who underwent liver resection were enrolled. HGS was measured using an electronic hand dynamometer. According to Clavien–Dindo classification, grade 2 or higher was considered as postoperative complication. The correlations between HGS and age/nutritional assessment tools were analysed using Spearman correlation test. Logistic regression analysis was used to determine the risk factors for complications. Results: About 25.2% of the patients had low HGS. The incidence rates of postoperative complications were 35.14% in the low-HGS group and 21.82% in the high-HGS group. HGS was negatively correlated with age (P < 0.05) in both sexes. Multivariate analysis showed that low HGS [odd ratio (OR) = 2.97, 95% CI: 1.07-8.25, P = 0.04] was related to postoperative complications in the total population. Conclusion: HGS is a risk factor for postoperative complications. Additional long-term studies are needed to confirm HGS as a valuable indicator before surgery.

scholarly journals HAND GRIP STRENGTH AS A NUTRITIONAL ASSESSMENT TOOL IN LONG-TERM CARE HOMES

2016 ◽  
Vol 1 (2) ◽  
pp. 1-11
Author(s):  
Susan J Whiting ◽  
Pui Chi Cheng ◽  
Lilian Thorpe ◽  
Navita Viveky ◽  
Jane Alcorn ◽  
...  
Keyword(s):  
Grip Strength ◽  
Long Term Care ◽  
Assessment Tool ◽  
Nutritional Assessment ◽  
Hand Grip Strength ◽  
Care Homes ◽  
Term Care ◽  
Hand Grip

scholarly journals Combination of the G-8 Screening Tool and Hand-Grip Strength to Predict Long-Term Overall Survival in Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3363
Author(s):  
Kristian Kirkelund Bentsen ◽  
Olfred Hansen ◽  
Jesper Ryg ◽  
Ann-Kristine Weber Giger ◽  
Stefan Starup Jeppesen
Keyword(s):  
Overall Survival ◽  
Grip Strength ◽  
Cancer Patients ◽  
Stereotactic Body Radiotherapy ◽  
Statistical Significance ◽  
Multivariable Analysis ◽  
Hand Grip Strength ◽  
Physical Test ◽  
Hand Grip

The Geriatric 8 (G-8) is a known predictor of overall survival (OS) in older cancer patients, but is mainly based on nutritional aspects. This study aimed to assess if the G-8 combined with a hand-grip strength test (HGST) in patients with NSCLC treated with stereotactic body radiotherapy can predict long-term OS better than the G-8 alone. A total of 46 SBRT-treated patients with NSCLC of stage T1-T2N0M0 were included. Patients were divided into three groups: fit (normal G-8 and HGST), vulnerable (abnormal G-8 or HGST), or frail (abnormal G-8 and HGST). Statistically significant differences were found in 4-year OS between the fit, vulnerable, and frail groups (70% vs. 46% vs. 25%, p = 0.04), as well as between the normal and abnormal G-8 groups (69% vs. 39%, p = 0.02). In a multivariable analysis of OS, being vulnerable with a hazard ratio (HR) of 2.03 or frail with an HR of 3.80 indicated poorer OS, but this did not reach statistical significance. This study suggests that there might be a benefit of adding a physical test to the G-8 for more precisely predicting overall survival in SBRT-treated patients with localized NSCLC. However, this should be confirmed in a larger study population.

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