International meeting on the nucleic acid vaccines for the prevention of infectious disease and regulating nucleic acid (DNA) vaccines

Vaccine ◽  
1996 ◽  
Vol 14 (13) ◽  
pp. 1285-1288 ◽  
Author(s):  
R.E. Spier
Keyword(s):  
Infectious Disease ◽  
Nucleic Acid ◽  
Dna Vaccines ◽  
International Meeting ◽  
Nucleic Acid Vaccines

scholarly journals Path to Success and Future Impact of Nucleic Acid Vaccines: DNA and mRNA

2021 ◽  
pp. 1-20
Author(s):  
Jeffrey B. Ulmer ◽  
Margaret A. Liu
Keyword(s):  
Nucleic Acid ◽  
Dna Vaccines ◽  
Rapid Development ◽  
Emerging Diseases ◽  
Human Pathogens ◽  
Vaccine Research ◽  
Safety Issues ◽  
Advantages And Disadvantages ◽  
Nucleic Acid Vaccines ◽  
Global Impacts

The rapid development of mRNA vaccines for COVID-19 has both astonished the world and raised concerns about their safety, perhaps because many people do not realize the decades’ long efforts for nucleic acid vaccines, both mRNA and DNA vaccines, including the licensure of several veterinary DNA vaccines. This manuscript traces the milestones for nucleic acid vaccine research and development (R&D), with a focus on the immune and safety issues they both raised and answered. The characteristics of the two entities are compared, demonstrating the similarities and differences between them, the advantages and disadvantages, which might lead toward using one or the other technology for different indications. In addition, as the SARS-CoV-2 pandemic has once again highlighted the importance of One Health, that is, the interactions between animal and human pathogens, focus will also be given to how DNA vaccine utilization and studies both in large domestic animals and in wildlife pave the way for more integrated approaches for vaccines to respond quickly to, and prevent, the global impacts of emerging diseases.

Prophylactic and Therapeutic DNA Vaccines Against Infectious Disease

2001 ◽  
pp. 275-294
Author(s):  
J. E. Kallman ◽  
H. C. Maguire ◽  
J. S. Yang ◽  
J. J. Kim ◽  
D. B. Weiner
Keyword(s):  
Infectious Disease ◽  
Dna Vaccines

scholarly journals Magnetic Particles for Advanced Molecular Diagnosis

Materials ◽  
2019 ◽  
Vol 12 (13) ◽  
pp. 2158 ◽  
Author(s):  
Cristina Chircov ◽  
Alexandru Mihai Grumezescu ◽  
Alina Maria Holban
Keyword(s):  
Gene Expression ◽  
Infectious Disease ◽  
Nucleic Acid ◽  
Sample Preparation ◽  
Molecular Diagnosis ◽  
Magnetic Particles ◽  
Early Stage ◽  
Disease Diagnosis ◽  
Laboratory Medicine ◽  
Clinical Reality

Molecular diagnosis is the field that aims to develop nucleic-acid-based analytical methods for biological markers and gene expression assessments by combining laboratory medicine and molecular genetics. As it gradually becomes a clinical reality, molecular diagnosis could benefit from improvements resulting from thorough studies that could enhance the accuracy of these methods. The application of magnetic particles in molecular diagnosis tools has led to tremendous breakthroughs in terms of specificity, sensitivity, and discrimination in bioassays. Therefore, the aim of this review is to highlight the principles involved in the implementation of magnetic particles for sample preparation and targeted analyte isolation, purification, and extraction. Furthermore, the most recent advancements in the area of cancer and infectious disease diagnosis are presented, with an emphasis on screening and early stage detection.

scholarly journals Portable sequencer in the fight against infectious disease

2019 ◽  
Vol 65 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Arthur Elia Mongan ◽  
Josef Sem Berth Tuda ◽  
Lucky Ronald Runtuwene
Keyword(s):  
Infectious Disease ◽  
Polymerase Chain Reaction ◽  
Nucleic Acid ◽  
Disease Management ◽  
Acid Composition ◽  
Molecular Techniques ◽  
Chain Reaction ◽  
Major Threat ◽  
The World ◽  
Polymerase Chain

Abstract Infectious disease is still a major threat in the world today. Five decades ago, it was considered soon to be eradicated, but the adaptation of pathogens to environmental pressure, such as antimicrobials, encouraged the emergence and reemergence of infectious disease. The fight with infectious disease starts with prevention, diagnosis, and treatment. Diagnosis can be upheld by observing the cause of disease under the microscope or detecting the presence of nucleic acid and proteins of the pathogens. The molecular techniques span from classical polymerase chain reaction (PCR) to sequencing the nucleic acid composition. Here, we are reviewing the works have been undertaken to utilize a portable sequencer, MinION, in various aspects of infectious disease management.

scholarly journals Planning an innovation marathon at an infectious disease conference with results from the International Meeting on Emerging Diseases and Surveillance 2016 Hackathon

2017 ◽  
Vol 65 ◽  
pp. 93-97 ◽  
Author(s):  
John W. Ramatowski ◽  
Christopher Xiang Lee ◽  
Aikaterini Mantzavino ◽  
João Ribas ◽  
Winter Guerra ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Emerging Diseases ◽  
International Meeting
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