Hypercoaulability state in central nervous system tumor patients

1997 ◽  
Vol 99 ◽  
pp. S251
Author(s):  
M.E. Kusak ◽  
J.M. Alonso ◽  
D. Santamarta ◽  
I. Recio ◽  
J.M. Borrás ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tumor ◽  
Tumor Patients ◽  
System Tumor

scholarly journals Central liponeurocytoma: Case report and review of literature

2012 ◽  
Vol 01 (01) ◽  
pp. 083-085 ◽  
Author(s):  
Pankaj Ailawadhi ◽  
M.C. Sharma ◽  
A.K. Mahapatra ◽  
P. Sarat Chandra
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tumor Classification ◽  
Central Nervous System Tumor ◽  
The Central Nervous System ◽  
Cerebellar Liponeurocytoma ◽  
Classification Of Tumors ◽  
System Tumor ◽  
Well Differentiated ◽  
Glioneuronal Tumors

Abstract Cerebellar liponeurocytoma consists of well-differentiated neurons with the cytology of neurocytes in addition to a population of lipidized cells. Hence it is biphasic in appearance and has been included in the category of glioneuronal tumors of the central nervous system by the WHO working group on the Classification of Tumors of the Nervous System. However, liponeurocytoma is not exclusive to the cerebellar or fourth ventricular location. Since its inclusion in the central nervous system tumor classification, nine cases with similar histological and immunohistochemical features have also been described in the lateral ventricles. We describe here such a lateral ventricular tumour in a 30-year-old woman, characteristically showing divergent glio-neuronal differentiation and lipidized neoplastic cells. Therefore, we suggest that future WHO tumor classification should consider that liponeurocytomas are not entirely restricted to the cerebellum and henceforth change of nomenclature might be considered, as also pointed out by other authors.

Expression of the RAG-2 gene in murine central nervous system tumor cell lines

1991 ◽  
Vol 181 (1) ◽  
pp. 151-158 ◽  
Author(s):  
Kei Tashiro ◽  
Toru Nakano ◽  
Tasuku Honjo ◽  
Tomokazu Aoki ◽  
Shin-ichi Miyatake ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tumor Cell ◽  
Cell Lines ◽  
Central Nervous System Tumor ◽  
Tumor Cell Lines ◽  
System Tumor

NCOG-42. SYMPTOM ONSET TO TIME OF DIAGNOSIS IN PRIMARY CENTRAL NERVOUS SYSTEM TUMOR PATIENTS: A REVIEW OF FINDINGS FROM THE NOB-NHS

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi161-vi161
Author(s):  
Matthew Lindsley ◽  
Elizabeth Vera ◽  
Alvina Acquaye ◽  
Nicole Briceno ◽  
Anna Choi ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Healthcare Providers ◽  
Healthcare Setting ◽  
Tumor Location ◽  
Low Grade ◽  
Central Nervous System Tumor ◽  
Tumor Patients ◽  
Patient Reported ◽  
Reported Data

Abstract Prior reports suggest the low prevalence of primary central nervous system (PCNS) tumors and the healthcare setting where patients seek care can contribute to diagnostic delays, potentially affecting prognosis. This descriptive report highlights findings from patient-reported data at presentation collected from a sample of 623 PCNS tumor patients. Participants were White (88%), males (56%), median age at diagnosis 41 (2-79) with high grade (HG) (66%) brain tumors (BT) (89%). Among BT patients, 30% reported ≥ 3 concurrent symptoms at presentation including headaches (40%), seizures (30%), and memory problems or difficulty with balance/walking (20% each). Over half (57%) had symptoms for < 6 months before diagnosis and 60% presented to the Emergency Room. Sixty-five percent of HG BT patients had symptoms for < 6 months prior to diagnosis compared to low grade (LG) tumors (40%) and had surgery in < 1 month from presentation (68% vs 51%, p < 0.01). More HG BT patients presented with weakness in the arms/legs than LG BT (14% vs 8%). Among spine tumor (ST) patients, 45% reported ≥ 3 concurrent symptoms at presentation including back pain (65%), sensory changes (45%), and weakness (40%). Almost half (46%) were symptomatic for > 1 year before diagnosis, presented in an outpatient clinic (64%) with 41% having surgery < 1 month from presentation. Younger (40% vs 16%) and HG ST patients (56% vs 21%) more often reported symptoms for < 6 months before diagnosis. HG ST patients more often presented to Emergency Rooms (67% vs 25%) and had surgery < 1 month from presentation (60% vs 36%). Further analysis of symptom presentation and clinical course is ongoing. Tumor location, grade, patient age and healthcare setting were associated with the time from clinical presentation to diagnosis. Development of aids providing guidance on diagnostic evaluation/treatment to front-line healthcare providers is warranted.

scholarly journals Diagnostic accuracy of squash cytology in central nervous system tumors

2017 ◽  
Vol 20 (1) ◽  
pp. 3-9
Author(s):  
Ram Kumar Shrestha ◽  
Bibek KC ◽  
Gopal Sedain ◽  
Gita Sayami ◽  
Sushil Shilpakar ◽  
...  
Keyword(s):  
Decision Making ◽  
Central Nervous System ◽  
Nervous System ◽  
Diagnostic Accuracy ◽  
Histopathological Examination ◽  
Biological Behavior ◽  
Central Nervous System Tumor ◽  
Quick Method ◽  
System Tumor ◽  
Method Of Evaluation

Introduction: CNS tumor requires intraoperative decision making regarding the extent of tumor removal. Clinical examination and imaging studies are not sufficient enough to predict the biological behavior of the tumors. Squash cytology is a quick method of evaluation of cytomorphologic features prepared from smear technique and provide the preliminary diagnosis and aid in intraoperative decision making by differentiating neoplastic from non neoplastic and benign from malignant lesions. The aim of this study is compare the diagnostic accuracy of squash cytology to that of histopathological examination. Methods: This study consists of 36 specimens from both brain and spine subjected to both squash cytology and histopathological evaluation. The squash preparation and histopathological finding were later compared and diagnostic accuracy calculated. Results: Gliomas are the most common tumor encountered and the accuracy of Squash cytology obtained was 71%. In meningioma, 100% diagnostic accuracy was obtained however, there was limitation in accurately predict the subgroup of tumor by squash cytology alone. Other neoplastic lesions included in this study were Schwannoma, Oligodendroglioma, Ependymoma, mixed tumors and others. Overall, the accuracy predicted by squash cytology is found to be 77.8 % in this study. Conclusion: Squash cytology is rapid and reliable method of tissue diagnosis that aid in intraoperative decision making regarding the extent of Central Nervous System tumor excision

scholarly journals QOL-52. USE OF CANNABINOIDS IN THE PEDIATRIC CENTRAL NERVOUS SYSTEM TUMOR POPULATION

2018 ◽  
Vol 20 (suppl_2) ◽  
pp. i168-i168
Author(s):  
Kathleen Dorris ◽  
Jessica Channell ◽  
Molly Hemenway ◽  
Angelina Baroffio ◽  
Michael Ellison ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tumor ◽  
System Tumor

Action observation therapy in pediatric patients with neuromotor deficits of the upper limbs secondary to central nervous system tumors

2019 ◽  
Vol 105 (6) ◽  
pp. NP75-NP78
Author(s):  
Marco Chisari ◽  
Raffaella Sensi ◽  
Carlo Alfredo Clerici ◽  
Fulvia Angela Gariboldi ◽  
Filippo Spreafico ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mirror Neurons ◽  
Action Observation ◽  
Case Series ◽  
Central Nervous System Tumor ◽  
Assessment Tests ◽  
System Tumor ◽  
Positive Results

This study reports a case series of patients with upper limb neuromotor deficits following pediatric central nervous system tumor and treated with rehabilitative therapy according to action observation therapy (AOT). AOT is based on the “mirror neurons” system and had positive results in various non-oncologic neurologic pathologies. This study is the first experience in the oncology field, and included 6 patients, 4 of whom were fully evaluated at 6-month follow-up. In all patients, therapy showed improvement in all assessment tests. These promising results lead to further studies to confirm their effectiveness.

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