Increased gene expression of β-amyloid precursor protein and its homologues APLP1 and APLP2 in human neuroblastoma cells in response to retinoic acid

1997 ◽  
Vol 221 (2-3) ◽  
pp. 73-76 ◽  
Author(s):  
Marie Beckman ◽  
Kerstin Iverfeldt
Keyword(s):  
Gene Expression ◽  
Retinoic Acid ◽  
Amyloid Precursor Protein ◽  
Neuroblastoma Cells ◽  
Precursor Protein ◽  
Human Neuroblastoma Cells ◽  
Human Neuroblastoma ◽  
Β Amyloid

Role of amyloid precursor protein (APP): Study with antisense transfection of human neuroblastoma cells

1992 ◽  
Vol 31 (4) ◽  
pp. 635-645 ◽  
Author(s):  
A. C. LeBlanc ◽  
D. M. Kovacs ◽  
H. Y. Chen ◽  
F. Villaré ◽  
M. Tykocinski ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Neuroblastoma Cells ◽  
Precursor Protein ◽  
Human Neuroblastoma Cells ◽  
Human Neuroblastoma

scholarly journals Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation.

1988 ◽  
Vol 8 (4) ◽  
pp. 1677-1683 ◽  
Author(s):  
C J Thiele ◽  
P S Cohen ◽  
M A Israel
Keyword(s):  
Retinoic Acid ◽  
Fetal Development ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cells ◽  
Human Neuroblastoma Cell ◽  
Human Neuroblastoma Cells ◽  
Human Neuroblastoma ◽  
Hematopoietic Lineage ◽  
Specific Manner ◽  
Neuroblastoma Cell Lines

We detected expression of the c-myb proto-oncogene, which was initially thought to be expressed in a tissue-specific manner in cells of hematopoietic lineage, in human tissues of neuronal origin. Since the level of c-myb expression declined during fetal development, we studied the regulation of its expression in human neuroblastoma cell lines induced to differentiate by retinoic acid. The expression of c-myb declined during the maturation of neuroblastoma cells, and this change was mediated by a decrease in c-myb transcription.

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