Met-enkephalin modulates lipid peroxidation and total sialic acid level in CBA mice in age- and sex-dependent manners

Maraş powder (MP), a different type of smokeless tobacco (ST) and prepared from a tobacco of speciesNicotiana rusticaLinn, is widely used in Turkey. We aimed to investigate the effects of MP on salivary total sialic acid (TSA) and malondialdehyde (MDA) levels and to compare these parameters in smokers and MP users (MPUs). The salivary TSA and MDA concentrations were significantly higher in the smokers and MPU than those of control subjects and also in MPU than that of smokers. We have also observed that as the number of cigarettes consumed and MP amount increases, TSA and MDA levels increase too. In smokers, MDA values were significantly correlated with the number of cigarettes smoked and the duration of smoking. In MPU, both MDA and TSA levels were significantly correlated with the duration of MP use and the amount of daily consumed MP. We have concluded increased salivary TSA and MDA levels associated in MPU and smokers. Results can help to evaluate harmful effects of these habits. It is important to point out that bigger change in the measured parameters has been observed for MP use. This observation may be an important indication of harmful effects of ST use as MP.

Download Full-text

The relationship between the levels of total sialic acid, lipid peroxidation and superoxide dismutase, catalase, glutathione peroxidase, ascorbate antioxidant in urea supplemented medium by Fusarium species

Enzyme and Microbial Technology ◽

10.1016/j.enzmictec.2005.12.005 ◽

2006 ◽

Vol 39 (4) ◽

pp. 697-702 ◽

Cited By ~ 3

Author(s):

Hulya Ayar Kayali ◽

Leman Tarhan

Keyword(s):

Lipid Peroxidation ◽

Superoxide Dismutase ◽

Sialic Acid ◽

Glutathione Peroxidase ◽

Fusarium Species ◽

Total Sialic Acid ◽

The Relationship

Download Full-text

Salivary Total Sialic Acid Levels Increase in Breast Cancer Patients: A Preliminary Study

Medicinal Chemistry ◽

10.2174/157340611796799230 ◽

2011 ◽

Vol 7 (5) ◽

pp. 443-447 ◽

Cited By ~ 16

Author(s):

Leyla Koc Ozturk ◽

Ebru Emekli-Alturfan ◽

Emel Kasikci ◽

Gokhan Demir ◽

Aysen Yarat

Keyword(s):

Breast Cancer ◽

Sialic Acid ◽

Cancer Patients ◽

Breast Cancer Patients ◽

Total Sialic Acid ◽

Preliminary Study

Download Full-text

Age- and sex-related differences in lipid peroxidation of mouse cardiac and skeletal muscles

Comparative Biochemistry and Physiology Part B Comparative Biochemistry ◽

10.1016/0305-0491(88)90310-0 ◽

1988 ◽

Vol 89 (4) ◽

pp. 695-699 ◽

Cited By ~ 5

Author(s):

A. Salminen ◽

P. Saari ◽

M. Kihlström

Keyword(s):

Lipid Peroxidation ◽

Skeletal Muscles ◽

Age And Sex

Download Full-text

Usefulness of sialic acid for diagnosis of sepsis in critically ill patients: a retrospective study

BMC Anesthesiology ◽

10.1186/s12871-020-01197-2 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Bo Yao ◽

Wen-juan Liu ◽

Di Liu ◽

Jin-yan Xing ◽

Li-juan Zhang

Keyword(s):

Sialic Acid ◽

Critically Ill ◽

Critically Ill Patients ◽

Incomplete Data ◽

Acid Level ◽

Operating Characteristic ◽

Area Under The Curve ◽

Diagnostic Efficacy ◽

Receiver Operating Characteristic Curves ◽

Sensitivity Specificity

Abstract Background Early diagnosis of sepsis is very important. It is necessary to find effective and adequate biomarkers in order to diagnose sepsis. In this study, we compared the value of sialic acid and procalcitonin for diagnosing sepsis. Methods Newly admitted intensive care unit patients were enrolled from January 2019 to June 2019. We retrospectively collected patient data, including presence of sepsis or not, procalcitonin level and sialic acid level. Receiver operating characteristic curves for the ability of sialic acid, procalcitonin and combination of sialic acid and procalcitonin to diagnose sepsis were carried out. Results A total of 644 patients were admitted to our department from January 2019 to June 2019. The incomplete data were found in 147 patients. Finally, 497 patients data were analyzed. The sensitivity, specificity and area under the curve for the diagnosis of sepsis with sialic acid, procalcitonin and combination of sialic acid and procalcitonin were 64.2, 78.3%, 0.763; 67.9, 84.0%, 0.816 and 75.2, 84.6%, 0.854. Moreover, sialic acid had good values for diagnosing septic patients with viral infection, with 87.5% sensitivity, 82.2% specificity, and 0.882 the area under the curve. Conclusions Compared to procalcitonin, sialic acid had a lower diagnostic efficacy for diagnosing sepsis in critically ill patients. However, the combination of sialic acid and procalcitonin had a higher diagnostic efficacy for sepsis. Moreover, sialic acid had good value for diagnosing virus-induced sepsis.

Download Full-text