scholarly journals Salivary Lipid Peroxidation and Total Sialic Acid Levels in Smokers and Smokeless Tobacco Users as Maraş Powder

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Naciye Kurtul ◽  
Engin Gökpınar

Maraş powder (MP), a different type of smokeless tobacco (ST) and prepared from a tobacco of speciesNicotiana rusticaLinn, is widely used in Turkey. We aimed to investigate the effects of MP on salivary total sialic acid (TSA) and malondialdehyde (MDA) levels and to compare these parameters in smokers and MP users (MPUs). The salivary TSA and MDA concentrations were significantly higher in the smokers and MPU than those of control subjects and also in MPU than that of smokers. We have also observed that as the number of cigarettes consumed and MP amount increases, TSA and MDA levels increase too. In smokers, MDA values were significantly correlated with the number of cigarettes smoked and the duration of smoking. In MPU, both MDA and TSA levels were significantly correlated with the duration of MP use and the amount of daily consumed MP. We have concluded increased salivary TSA and MDA levels associated in MPU and smokers. Results can help to evaluate harmful effects of these habits. It is important to point out that bigger change in the measured parameters has been observed for MP use. This observation may be an important indication of harmful effects of ST use as MP.

2005 ◽  
Vol 12 (3) ◽  
pp. 559-563 ◽  
Author(s):  
Naciye Kurtul ◽  
M. Yaşar Çil ◽  
Sefa Doğruluk Paçacı ı

Author(s):  
Isa Kiran ◽  
Suat Ekin ◽  
Özge Vural

Abstract. In this study, children with vitamin B12 deficiency anemia (V-B12DA) and control subjects were evaluated for erythrocyte glutathione peroxidase, catalase and superoxide dismutase enzyme activities, glutathione, malondialdehyde, serum total sialic acid, total antioxidant status, cobalt, chromium, copper, selenium, vanadium, zinc, iron, lead, magnesium, calcium, sodium, potassium, chloride, phosphorus levels, and the associations of these variables were assessed. The study included 50 children with V-B12DA and 50 control subjects. It was found that the V-B12DA group was significantly lower than the control group, with regard to the mean±the standard error of the mean levels of cobalt (0.089±0.009; 0.058±0.0063 μmol/L, p<0.01), selenium (2.19±0.087; 1.88±0.057 μmol/L, p<0.01), vanadium (1.31±0.053; 1.18±0.035 μmol/L, p<0.05), magnesium (3.02±0.15; 2.73±0.068 μmol/L, p<0.05), zinc (50.76±1.96; 42.23± 1.53 μmol/L, p<0.001), and vitamin B12 (427.20±21.45; 157.08±3.96 pg/mL, p<0.001). Moreover, a significant elevation in total sialic acid (1.44±0.050; 1.61±0.043 mmol/L, p<0.01), and mean corpuscular volume (MCV) (75.37±0.95; 79.91±1.14 fL, p<0.01). It was observed that in the V-B12DA, significantly linear correlations were observed between cobalt – vitamin B12 (r=0.334; p=0.025), vanadium – MCV (r=0.315; p=0.017), vitamin B12 – MCV (r=−0.297; p=0.026). The findings of the study indicated that the levels of cobalt, vanadium significantly associated with traditional vitamin B12-deficiency parameters. Vitamin B12 and MCV should be measured together with cobalt, vanadium for monitoring the vitamin B12 deficiency anemia.


2010 ◽  
Vol 43 (4-5) ◽  
pp. 430-434 ◽  
Author(s):  
L. Koç Öztürk ◽  
S. Akyüz ◽  
A. Yarat ◽  
S. Koç ◽  
N. Gül ◽  
...  

2006 ◽  
Vol 49 (2) ◽  
pp. 97-100
Author(s):  
Naciye Kurtul ◽  
Burcu Canter Arikan

Pesticides used to increase agricultural production have hazard effects for human being health. The present study reports the serum levels of total sialic acid (TSA) in the pesticide applicators in the agriculture areas of the Kahramanmaras, Turkiye. This study included a total of 79 volunteer individuals. Pesticide group included 47 men who were working as pesticide applicators. Control group comprised healthy males (n=32), nonsmokers and nondrinkers and also nonexposured to pesticide and other chemicals chronically. Serum TSA level was measured with the Warren method modified by Pönniö et al. The TSA concentrations were significantly higher in the pesticide groups (p<0.001) than those of control subjects. We can conclude from the results obtained that serum TSA was affected by pesticide exposure. This finding may be an indication of harmful effects of pesticides. Increased serum TSA levels in pesticide exposure might be related to various diseases e.g. various cancers, which are also often associated with elevated serum TSA levels. However further studies are necessary to evaluate the concentrations of serum TSA in pesticide exposure.


Author(s):  
Adil Doğan ◽  
Nuray Bayar Muluk ◽  
Yılmaz Inanç

Abstract Objective In the present study, we investigated the efficacy of Maraş powder (smokeless tobacco) use on smell regions in migraine patients. Methods The cranial magnetic resonance imaging images of 58 adult patients were included in this retrospective study. Thirty-eight of them were migraine patients (18 of them using Maraş powder and 20 of them not using Maraş powder) and 20 of them were healthy controls. Bilateral peripheral (olfactory bulb [OB] volume and olfactory sulcus depth) and central smell regions (insular gyrus area and corpus amygdala area) as well as nasal septal deviation were evaluated. Results In migraine patients (using or not using Maraş powder), OB volumes, and in Maraş powder using migraine patients, corpus amygdala areas were lower than those in the control group (p < 0.05). In Maraş powder-using migraine patients, left insular gyrus areas of the females were significantly lower than the males (p < 0.05). Conclusion We concluded that the peripheral smell region of the OB volume decreased in migraine patients (using or not using Maraş powder). However, the central smell region of corpus amygdala area decreased in Maraş powder using migraine patients. Maraş powder usage may increase vascular shrinkage, and the decrease in OB volume and corpus amygdala area becomes prominent. It can be said that Maraş powder usage may cause a size decrease in the peripheral and central smell regions in migraine patients. Therefore, migraine patients and non-migrainous people should be noticed for the harmful effects of Maraş powder on the vascular system and smell system in the aspects of OB volume and corpus amygdala area decrease.


2002 ◽  
Vol 37 (12) ◽  
pp. 1413-1421 ◽  
Author(s):  
Višnja Šverko ◽  
Sandra Sobočanec ◽  
Tihomir Balog ◽  
Tatjana Marotti

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