scholarly journals Short-Term Antihypertensive Medication Does Not Exacerbate Sleep-Disordered Breathing in Newly Diagnosed Hypertensive Patients

1997 ◽  
Vol 10 (6) ◽  
pp. 640-645 ◽  
Author(s):  
P Bartel
2012 ◽  
Vol 28 (6) ◽  
pp. 728-734 ◽  
Author(s):  
Akiomi Yoshihisa ◽  
Satoshi Suzuki ◽  
Takashi Owada ◽  
Shoji Iwaya ◽  
Hiroyuki Yamauchi ◽  
...  

2009 ◽  
Vol 53 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Taiji Furukawa ◽  
Masaaki Suzuki ◽  
Ikuko Funatogawa ◽  
Takaaki Isshiki ◽  
Yukihisa Miyazawa ◽  
...  

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Michael Dreher ◽  
Stefan Krüger ◽  
Susanne Schulze-Olden ◽  
András Keszei ◽  
Jan Hendrik Storre ◽  
...  

2015 ◽  
Vol 46 (5) ◽  
pp. 1361-1369 ◽  
Author(s):  
Gerhard Weinreich ◽  
Thomas E. Wessendorf ◽  
Noreen Pundt ◽  
Gudrun Weinmayr ◽  
Frauke Hennig ◽  
...  

Scarce evidence suggests that ambient air pollution and temperature might play a role in incidence and severity of sleep disordered breathing (SDB). We investigated the association of short-term exposure to fine particulate matter (particles with a 50% cut-off aerodynamic diameter of 10 μm (PM10)), ozone and temperature with SDB in the general population.Between 2006 and 2008, 1773 participants (aged 50–80 years) of the Heinz Nixdorf Recall study underwent screening for SDB, as defined by the apnoea–hypopnoea index (AHI). We assessed daily exposure to PM10, ozone, temperature and humidity. We used multiple linear regression to estimate associations of daily PM10, ozone levels and temperature on the day of screening, adjusting for relative humidity, season, age, sex, body mass index, education, smoking habits, alcohol consumption and physical activity.In the study population, the mean±sdAHI was 11.2±11.4 events·h−1. Over all seasons, an interquartile range increase in temperature (8.6°C) and ozone (39.5 µg·m−3) was associated with a 10.2% (95% CI 1.2–20.0%) and 10.1% (95% CI 2.0–18.9%) increase in AHI, respectively. Associations for temperature were stronger in summer, yielding a 32.4% (95% CI 0.0–75.3%) increase in AHI per 8.6°C (p-value for season–temperature interaction 0.08). We observed that AHI was not associated with PM10.This study suggests that short-term variations in ozone concentration and temperature are associated with SDB.


2020 ◽  
Vol 15 (1) ◽  
pp. 42-44
Author(s):  
Mst Nasrin Nahar ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Tamanna Habib

Introduction: Essential hypertension is associated with altered pulmonary function. Antihypertensive medication and lung function are also associated. Losartan (angiotensin II receptor blocker) and amlodipine (calcium channel blocker) are commonly used antihypertensive drugs. Objectives: To evaluate the effects of antihypertensive drugs on lung function status in patients with essential hypertension. Materials and Methods: This prospective observational study was carried out in the Department of Physiology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, from July 2012 to June 2013 on 100 newly diagnosed hypertensive patients without any antihypertensive medication (group B, age 30-55 years). They were selected from the Out Patient Department (OPD) of Cardiology, BSMMU, Dhaka. Age, sex and BMI matched 50 apparently healthy normotensive subjects were also studied as control (group A). Based on treatment, these study subjects were divided into two groups (B1 and B2). Group B1 included 50 patients received losartan 50 mg daily and B2 included 50 patients received amlodipine 5 mg daily. They were observed once before the treatment (B1a and B2a), after 3 months of medication (B1b and B2b) and after 6 months of medication (B1c and B2c). For assessing lung function status, Forced Vital Capacity (FVC), Forced Expiratory Volume in 1st second (FEV1) and Peak Expiratory Flow Rate (PEFR) were measured with a RMS computer based Spirometer. Results: Mean FVC, FEV1 and PEFR were significantly lower in newly diagnosed hypertensive patients in comparison with that of healthy normotensive. Mean FVC, FEV1 and PEFR were found significantly higher in the group taking losartan and amlodipine for 6 months when compared to newly diagnosed but lower than those of controls. Conclusion: Reduced lung function occurs in newly diagnosed hypertensive patients which was improved by treatment with losartan and amlodipine. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 42-44


2005 ◽  
Vol 54 (4) ◽  
pp. 325-333
Author(s):  
KAZUNORI OHKAWARA ◽  
KIYOJI TANAKA ◽  
FUMIO NAKADOMO ◽  
YOSHIO NAKATA ◽  
YASUTOMI KATAYAMA ◽  
...  

Respirology ◽  
2010 ◽  
Vol 15 (2) ◽  
pp. 272-276 ◽  
Author(s):  
Khoa TRAN ◽  
Craig HUKINS ◽  
Timothy GERAGHTY ◽  
Brenton ECKERT ◽  
Lynne FRASER

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