098 THE IMPACT OF VALVE SURGERY ON SHORT-AND LONG-TERM MORTALITY IN LEFT-SIDED INFECTIVE ENDOCARDITIS

2009 ◽  
Vol 33 ◽  
pp. S38 ◽  
Author(s):  
A. Bannay ◽  
B. Hoen ◽  
X. Duval ◽  
J. Obaida ◽  
C. Selton-Suty ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Valve Surgery ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

Abstract 19771: Persistent Thrombocytopenia after Myocardial Infarction is Associated with Increased Short- and Long-Term Mortality

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Anirudh Kumar ◽  
Salim Virani ◽  
Scott Bassett ◽  
Mahboob Alam ◽  
Ravi Hira ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Bleeding Complications ◽  
Group Differences ◽  
Long Term Outcomes ◽  
Post Discharge ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

Background: Thrombocytopenia (TCP) occurs commonly in patients hospitalized with acute myocardial infarction (AMI). It is unclear whether persistent TCP after discharge among AMI survivors is associated with worse outcomes. Methods: We examined the impact of persistent post-discharge TCP on outcomes in a registry of consecutive AMI patients hospitalized between January 2004 and December 2007. In-hospital (IH) TCP was defined by a nadir platelet count < 150 x 109/L. Resolved TCP was defined as IH TCP which resolved within 3 months after discharge while persistent TCP was defined as IH TCP which did not resolve within 3 months. Results: Of 842 patients hospitalized for a first AMI, we examined data on 617 hospital survivors who had follow-up within 3 months of discharge and documented long-term outcomes. Of those, 474 (76.8%) patients did not experience IH TCP while 42 (6.8%) and 101 (16.4%) had persistent and resolved TCP, respectively (Table). Patients with persistent TCP were older, had worse comorbidities, and were more likely to have TCP at baseline and discharge. There were no inter-group differences in infarct size, major bleeding complications, revascularization, or ejection fraction at discharge. Mortality following discharge was higher at all time-points among AMI patients with persistent TCP compared to patients with resolved or without IH TCP (Figure). Patients with resolved TCP had comparable mortality to those without IH TCP. Conclusion: Persistent TCP within 3 months after hospital discharge for AMI is associated with significantly increased short- and long-term mortality compared to patients with recovered TCP or without IH TCP.

scholarly journals The impact of body mass index on morbidity and short- and long-term mortality in cardiac valvular surgery

2011 ◽  
Vol 142 (5) ◽  
pp. 1052-1061 ◽  
Author(s):  
Vinod H. Thourani ◽  
W. Brent Keeling ◽  
Patrick D. Kilgo ◽  
John D. Puskas ◽  
Omar M. Lattouf ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Valvular Surgery ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

The impact of admission neutrophil-to-platelet ratio on in-hospital and long-term mortality in patients with infective endocarditis

2017 ◽  
Vol 55 (6) ◽  
pp. 899-906 ◽  
Author(s):  
Xue-biao Wei ◽  
Yuan-hui Liu ◽  
Peng-cheng He ◽  
Dan-qing Yu ◽  
Ning Tan ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Proportional Hazards ◽  
Hazard Analysis ◽  
Cox Proportional Hazards ◽  
Adverse Outcomes ◽  
Rapid Screening ◽  
Hospital Death ◽  
The Impact ◽  
Long Term Mortality

Abstract Background: Infective endocarditis (IE) is associated with increased neutrophil and reduced platelet counts. We assessed the relationship between the neutrophil-to-platelet ratio (NPR) on admission and adverse outcomes in patients with IE. Methods: Patients diagnosed with IE between January 2009 and July 2015 (n=1293) were enrolled, and 1046 were finally entered into the study. Study subjects were categorized into four groups according to NPR quartiles: Q1<18.9 (n=260); Q2: 18.9–27.7 (n=258); Q3: 27.7–43.3 (n=266); and Q4>43.3 (n=262). Cox proportional hazards regression was performed to identify risk factors for long-term mortality; the optimal cut-off was evaluated by receiver operating characteristic curves. Results: Risk of in-hospital death increased progressively with NPR group number (1.9 vs. 5.0 vs. 9.8 vs. 14.1%, p<0.001). The follow-up period was a median of 28.8 months, during which 144 subjects (14.3%) died. Long-term mortality increased from the lowest to the highest NPR quartiles (7.6, 11.8, 17.4, and 26.2%, respectively, p<0.001). Multivariate Cox proportional hazard analysis revealed that lgNPR (HR=2.22) was an independent predictor of long-term mortality. Kaplan-Meier survival curves showed that subjects in Q4 had an increased long-term mortality compared with the other groups. Conclusions: Increased NPR was associated with in-hospital and long-term mortality in patients with IE. As a simple and inexpensive index, NPR may be a useful and rapid screening tool to identify IE patients at high risk of mortality.

scholarly journals TCT-686 The Impact of Coronary Artery Disease and Pre-Procedural PCI on the Short- and Long-Term Mortality After TAVR

2019 ◽  
Vol 74 (13) ◽  
pp. B673
Author(s):  
Thomas van den Boogert ◽  
Jetske Gunster ◽  
Martijn van Mourik ◽  
Jeroen Vendrik ◽  
Bimmer Claessen ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Short And Long Term ◽  
Artery Disease ◽  
The Impact ◽  
Long Term Mortality

Impact of Pulmonary Artery Catheter Use on Short- and Long-Term Mortality in Patients with Cardiogenic Shock

Cardiology ◽  
2016 ◽  
Vol 136 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Xavier Rossello ◽  
Montserrat Vila ◽  
Mercedes Rivas-Lasarte ◽  
Andreu Ferrero-Gregori ◽  
Jordi Sans-Roselló ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Cardiogenic Shock ◽  
Mortality Rates ◽  
Coronary Syndrome ◽  
Short Term Mortality ◽  
Long Term Follow Up ◽  
Short And Long Term ◽  
The Impact ◽  
Long Term Mortality

Objectives: The impact of pulmonary artery catheterization (PAC) on survival in patients with cardiogenic shock (CS) is not well established. This study aimed to assess whether Swan-Ganz catheter monitoring is related to short- and long-term mortality in patients with CS. Methods: One hundred and twenty-nine consecutive patients with a first admission for CS were prospectively enrolled in a single-center registry between December 2005 and May 2009, and were subsequently followed up over 5.3 years. Results: PAC was used in 64% of all patients with a mean age of 68 years (65% men). After adjustment for age, gender and the presence of CS upon admission, PAC was associated with lower short-term mortality [hazard ratio (HR) = 0.55, 95% confidence interval (CI) 0.35-0.86, p = 0.008] as well as lower mortality rates in the long-term follow-up (HR = 0.63, 95% CI 0.41-0.97, p = 0.035). In a subgroup analysis, the use of PAC was associated with reduced mortality in patients without acute coronary syndrome (ACS), i.e. 49% in the Swan-Ganz group vs. 82% (p = 0.010), but there was no difference within the ACS group. Conclusions: The use of PAC in patients with CS was associated with lower short- and long-term mortality rates after adjustment for age, gender and the presence of shock upon admission. This benefit was only significant in those patients without ACS.

Short- and long-term mortality in patients with left-sided infective endocarditis not undergoing surgery despite indication

2020 ◽  
Vol 73 (9) ◽  
pp. 734-740
Author(s):  
Nuria Vallejo Camazón ◽  
Germán Cediel ◽  
Raquel Núñez Aragón ◽  
Lourdes Mateu ◽  
Cinta Llibre ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Short And Long Term ◽  
Long Term Mortality

Short- and long-term mortality after deep sternal wound infection following cardiac surgery: experiences from SWEDEHEART

2021 ◽  
Author(s):  
Alexander Emil Kaspersen ◽  
Susanne J Nielsen ◽  
Andri Wilberg Orrason ◽  
Astridur Petursdottir ◽  
Martin Ingi Sigurdsson ◽  
...  
Keyword(s):  
Wound Infection ◽  
Valve Surgery ◽  
Absolute Difference ◽  
Deep Sternal Wound Infection ◽  
Adjusted Relative Risk ◽  
Sternal Wound Infection ◽  
All Cause Mortality ◽  
Short And Long Term ◽  
Long Term Mortality

Abstract Graphical Abstract OBJECTIVES Deep sternal wound infection (DSWI) is a serious complication after open-heart surgery. We investigated the association between DSWI and short- and long-term all-cause mortality in a large well-defined nationwide population. METHODS A retrospective, nationwide cohort study, which included 114 676 consecutive patients who underwent coronary artery bypass grafting (CABG) and/or valve surgery from 1997 to 2015 in Sweden. Short- and long-term mortality was compared between DSWI patients and non-DSWI patients using propensity score inverse probability weighting adjustment based on patient characteristics and comorbidities. Median follow-up was 8.0 years (range 0–18.9). RESULTS Altogether, 1516 patients (1.3%) developed DSWI, most commonly in patients undergoing combined CABG and valve surgery (2.1%). DSWI patients were older and had more disease burden than non-DSWI patients. The unadjusted cumulative mortality was higher in the DSWI group compared with the non-DSWI group at 90 days (7.9% vs 3.0%, P &lt; 0.001) and at 1 year (12.8% vs 4.5%, P &lt; 0.001). The adjusted absolute difference in risk of death was 2.3% [95% confidence interval (CI): 0.8–3.9] at 90 days and 4.7% (95% CI: 2.6–6.7) at 1 year. DSWI was independently associated with 90-day [adjusted relative risk (aRR) 1.89 (95% CI: 1.38–2.59)], 1-year [aRR 2.13 (95% CI: 1.68–2.71)] and long-term all-cause mortality [adjusted hazard ratio 1.56 (95% CI: 1.30–1.88)]. CONCLUSIONS Both short- and long-term mortality risks are higher in DSWI patients compared to non-DSWI patients. These results stress the importance of preventing these infections and careful postoperative monitoring of DSWI patients.

scholarly journals Characteristics and Outcomes In Patients With Left-Sided Infective Endocarditis Undergoing Left-Sided Valve Surgery With or Without Concomitant Tricuspid Annuloplasty

2021 ◽  
Author(s):  
Zexuan Wu ◽  
Yuanyuan Zhou ◽  
Yili Chen ◽  
Fangfei Wei ◽  
Zi Ye ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Postoperative Complications ◽  
Clinical Features ◽  
Left Ventricular ◽  
Valve Surgery ◽  
Right Atrial ◽  
Average Hospital ◽  
Tricuspid Annuloplasty ◽  
Long Term Mortality

Abstract Background: In patients with left-sided infective endocarditis (LSIE) undergoing left-sided valve surgery (LVS), the effects of concomitant tricuspid annuloplasty (TA) on clinical features and prognosis remain unknown. Methods: This is a single-center retrospective study conducted in a tertiary hospital in China. A total of 207 consecutive patients ≥18 years with a definite LSIE diagnosis who underwent LVS between 2008 and 2017 were included. Patients were divided into two groups: LVS alone (n=157) and LVS+TA group (n=50), to identify differences between the clinical features, echocardiogdraphic parameters and outcomes.Results: The mean age was 44.6±15.6 years and 150 (72.5%) were male. Of the 207 patients, 71 (34.3%) patients had aortic valve involved alone, 115 (55.6%) had mitral valve involved alone and 21 (10.1%) had both valved involved. The average hospital stays were 38±16 days and the median follow-up duration was 34.4 (IQR 19.8-56.3) months. Demographic and baseline characteristics were comparable between the two groups, except that the renal function in LVS alone group was better than LVS +TA group (eGFR 97.2±28.8 vs. 87.6±30.7, P=0.046). Significant reductions in left and right atrial diameter, left ventricular diameter, mitral and tricuspid regurgitation (TR) degree, and pulmonary arterial systolic pressure were reported in both groups, of which the differences were more prominent in LVS+ TA group than LVS alone group (P<0.05). The rate of postoperative complications was higher in LVS+ TA group than that in LVS group (44.0% vs. 23.6%, P=0.005). However, the in-hospital mortality and long-term mortality was similar in both groups. After multi-factor adjustment, concomitant TA was not significantly associated with in-hospital and long-term mortality.Conclusions: Concomitant TA at the time of LVS significantly improved cardiac diameter but increased postoperative complications. It might not be associated with improved survival in LSIE patients.

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