7054 POSTER Concurrent Histone Deacetylase and Mammalian Target of Rapamycin Inhibition Attenuate Androgen Receptor and Hypoxia Signaling Associated With Alterations in MicroRNA Expression

European Journal of Cancer ◽

10.1016/s0959-8049(11)72005-6 ◽

2011 ◽

Vol 47 ◽

pp. S501

Author(s):

L. Ellis ◽

K. Lehet ◽

S. Ramakrishnan ◽

K.M. Miles ◽

D. Wang ◽

...

Keyword(s):

Androgen Receptor ◽

Histone Deacetylase ◽

Mammalian Target Of Rapamycin ◽

Microrna Expression ◽

Target Of Rapamycin ◽

Hypoxia Signaling

Download Full-text

Post-Transcriptional Regulation of the Androgen Receptor by Mammalian Target of Rapamycin

Cancer Research ◽

10.1158/0008-5472.can-04-3411 ◽

2005 ◽

Vol 65 (7) ◽

pp. 2547-2553 ◽

Cited By ~ 46

Author(s):

Bekir Cinar ◽

Arrigo De Benedetti ◽

Michael R. Freeman

Keyword(s):

Transcriptional Regulation ◽

Androgen Receptor ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Post Transcriptional Regulation

Download Full-text

Combination Strategy Targeting the Hypoxia Inducible Factor-1α with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-4306 ◽

2008 ◽

Vol 14 (11) ◽

pp. 3589-3597 ◽

Cited By ~ 81

Author(s):

Henk M.W. Verheul ◽

Brenda Salumbides ◽

Karen Van Erp ◽

Hans Hammers ◽

David Z. Qian ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Mammalian Target Of Rapamycin ◽

Hypoxia Inducible Factor ◽

Target Of Rapamycin ◽

Combination Strategy ◽

Hypoxia Inducible Factor 1Α

Download Full-text

Effects of tetrandrine and caffeine on cell viability and expression of mammalian target of rapamycin, phosphatase and tensin homolog, histone deacetylase 1, and histone acetyltransferase in glioma cells

Tzu Chi Medical Journal ◽

10.1016/j.tcmj.2015.03.002 ◽

2015 ◽

Vol 27 (2) ◽

pp. 74-78 ◽

Cited By ~ 1

Author(s):

Jin-Cherng Chen ◽

Yin-Ching Chan ◽

Juen-Haur Hwang

Keyword(s):

Cell Viability ◽

Histone Deacetylase ◽

Histone Acetyltransferase ◽

Mammalian Target Of Rapamycin ◽

Glioma Cells ◽

Target Of Rapamycin ◽

Phosphatase And Tensin Homolog ◽

Histone Deacetylase 1 ◽

Tensin Homolog

Download Full-text

236 PREVENTION OF RESISTANCE DEVELOPMENT IN RENAL CELL CARCINOMA BY COMBINED INHIBITION OF HISTONE DEACETYLASE AND MAMMALIAN TARGET OF RAPAMYCIN

The Journal of Urology ◽

10.1016/j.juro.2011.02.305 ◽

2011 ◽

Vol 185 (4S) ◽

Author(s):

Eva Juengel ◽

Anna Vogt ◽

Lukasz Hudak ◽

Jasmina Makarevic ◽

Axel Haferkamp ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Histone Deacetylase ◽

Renal Cell ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Resistance Development

Download Full-text

Discovery of Novel Dual Histone Deacetylase and Mammalian Target of Rapamycin Target Inhibitors as a Promising Strategy for Cancer Therapy

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b01825 ◽

2019 ◽

Vol 62 (3) ◽

pp. 1577-1592 ◽

Cited By ~ 12

Author(s):

Yong Chen ◽

Xue Yuan ◽

Wanhua Zhang ◽

Minghai Tang ◽

Li Zheng ◽

...

Keyword(s):

Cancer Therapy ◽

Histone Deacetylase ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Promising Strategy

Download Full-text

Concurrent HDAC and mTORC1 Inhibition Attenuate Androgen Receptor and Hypoxia Signaling Associated with Alterations in MicroRNA Expression

PLoS ONE ◽

10.1371/journal.pone.0027178 ◽

2011 ◽

Vol 6 (11) ◽

pp. e27178 ◽

Cited By ~ 11

Author(s):

Leigh Ellis ◽

Kristin Lehet ◽

Swathi Ramakrishnan ◽

Remi Adelaiye ◽

Kiersten M. Miles ◽

...

Keyword(s):

Androgen Receptor ◽

Microrna Expression ◽

Hypoxia Signaling

Download Full-text

Faculty Opinions recommendation of Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002644.29305 ◽

2001 ◽

Author(s):

Ron Schwartz

Keyword(s):

Cell Cycle ◽

Cell Cycle Progression ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Cycle Progression ◽

Recall Antigen ◽

Clonal Anergy

Download Full-text

Faculty Opinions recommendation of Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13420972.15108061 ◽

2012 ◽

Author(s):

Rony Seger ◽

Zhong Yao

Keyword(s):

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Multiple Site

Download Full-text

Faculty Opinions recommendation of The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14253971.15768075 ◽

2012 ◽

Author(s):

Joseph Avruch ◽

Angela Papageorgiou

Keyword(s):

Gene Expression ◽

Mammalian Target Of Rapamycin ◽

Transcriptional Profile ◽

Target Of Rapamycin ◽

Biosynthetic Gene ◽

Biosynthetic Gene Expression

Download Full-text

Faculty Opinions recommendation of Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717976173.793470470 ◽

2013 ◽

Author(s):

Phyllis Leppert

Keyword(s):

G Protein ◽

Mammalian Target Of Rapamycin ◽

Uterine Fibroids ◽

Target Of Rapamycin ◽

G Protein Coupled Receptor ◽

G Protein Coupled

Download Full-text