scholarly journals 0223 Bilateral breast carcinoma - synchronous and metachronous lesion - a retrospective analysis from a tertiary center in South India

The Breast ◽  
2009 ◽  
Vol 18 ◽  
pp. S74
Author(s):  
B. Selvan ◽  
A. Nair ◽  
S. John
Keyword(s):  
Breast Carcinoma ◽  
Retrospective Analysis ◽  
South India ◽  
Tertiary Center ◽  
Metachronous Lesion ◽  
Bilateral Breast Carcinoma

A Case of Extramammary Paget's Disease after Excision of Bilateral Breast Carcinoma

2007 ◽  
Vol 69 (3) ◽  
pp. 273-276
Author(s):  
Satoko KUMAZAWA ◽  
Kou DAN ◽  
Teiichi MASUDA ◽  
Kazunori URABE ◽  
Masutaka FURUE
Keyword(s):  
Breast Carcinoma ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Bilateral Breast Carcinoma ◽  
Extramammary Paget's Disease

scholarly journals Defibrillation success after subcutaneous implantable cardioverter-defibrillator generator replacement is not affected by impedance increase

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
W Van Der Stuijt ◽  
S Pepplinkhuizen ◽  
ABE Quast ◽  
L Smeding ◽  
LRA Olde Nordkamp ◽  
...  
Keyword(s):  
Ventricular Arrhythmia ◽  
Success Rate ◽  
Implantable Cardioverter Defibrillator ◽  
Retrospective Analysis ◽  
Analysis Data ◽  
Cardioverter Defibrillator ◽  
Replacement Procedure ◽  
Shock Impedance ◽  
Tertiary Center ◽  
Generator Replacement

Abstract Funding Acknowledgements Type of funding sources: None. Background Routine defibrillation testing during implant and replacement of the subcutaneous implantable cardioverter-defibrillator (S-ICD) is recommended per current guidelines. Recently, concerns have been raised about an increase in shock impedance and consequent shock failure during defibrillation testing in S-ICD patients undergoing a generator replacement. Purpose We aim to describe the defibrillation success rate in relation to the shock impedance in patients undergoing S-ICD generator replacement in our large tertiary center. Methods In this retrospective analysis, data from replacement procedures were collected from all patients who underwent an S-ICD generator replacement in our center from June 2014 to December 2020. Defibrillation testing was performed with at least one shock of ≤65J, and a successful shock was defined as terminating the ventricular arrhythmia within 5 seconds after the shock. Results A total of 133 patients underwent an S-ICD generator replacement, 5.8 ± 0.9 years after initial implant. Reasons for replacement were: reaching of elective replacement indicator (n = 119), early battery depletion (n = 9), complaints of generator pocket (n = 3) and device malfunction (n = 2). Defibrillation testing was performed in 111 patients (86.5%) undergoing a replacement procedure. Shock impedance data from both the implant and replacement procedure were available in 101 patients. The median shock impedance of these patients during their replacement procedure was significantly higher than during their implant, 79Ω (IQR 66-94) and 66Ω (IQR 57.5-81) respectively (Z = -5.552, p < 0.001). Despite the higher shock impedance, first shock during defibrillation testing was successful in 105/111 patients (94.6%), with a success rate of 97.3% after two attempts. In the remaining three patients, the ventricular arrhythmia could only be terminated with a 80J shock. This was the case during both their initial implant and their replacement procedure. Shock impedance increase between implant and replacement was not significantly higher in patients with a successful first shock compared to patients with an unsuccessful first shock (Δ+11.1 ± 20.0Ω versus Δ+12.7 ± 27.6Ω, p = 0.86). Conclusion In this large retrospective analysis, we have shown a first shock success rate during S-ICD generator replacement of 94.6%, which is similar to the success rate of defibrillation testing after initial implant. After multiple attempts, defibrillation testing success rate was 100%. Even though the median shock impedance during replacement was significantly higher than during the initial implant, there was no difference in impedance increase in patients with a successful shock compared to patients with an unsuccessful shock. Abstract Figure. Defibrillation success

scholarly journals A Case of Metachronous Bilateral Breast Carcinoma Detected by Screening Mammography and Histologically Defined as Apocrine Carcinoma

2011 ◽  
Vol 61 (4) ◽  
pp. 531-535
Author(s):  
Michio Maemura ◽  
Takashi Roppongi ◽  
Kotaro Iwanami ◽  
Yuki Numaga ◽  
Miki Tsuboi ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Screening Mammography ◽  
Apocrine Carcinoma ◽  
Bilateral Breast Carcinoma

scholarly journals PARANASAL SINUS MUCOCELE AND ITS COMPLICATIONS: RETROSPECTIVE ANALYSIS AND LITERATURE REVIEW

2021 ◽  
pp. 1-3
Author(s):  
Sudhagar Eswaran ◽  
Namrataa S ◽  
Prasanna Kumar S
Keyword(s):  
Skull Base ◽  
Retrospective Analysis ◽  
Paranasal Sinus ◽  
Paranasal Sinuses ◽  
Vision Loss ◽  
Delay In Diagnosis ◽  
Diagnosis And Management ◽  
Audit Data ◽  
Tertiary Center ◽  
Skull Base Defect

BACKGROUND: Mucocele is a true cystic expansile mass filled with mucus resulting from obstruction of the sinus ostia. Prompt diagnosis and management are needed to avoid complications due to the intracranial or intra-orbital extension. OBJECTIVES: To audit data of mucocele of the paranasal sinuses in a tertiary center, to review the literature regarding the clinical features and the management of mucocele in the paranasal sinus and to emphasize the iatrogenic causes of mucocele after the development of Endoscopic Skull Base Surgeries. MATERIALS AND METHODS: A retrospective analysis of etiology, clinical presentation, sinuses involved, operative technique, complication, recurrence were interpreted. RESULTS: The mean age of 16 patients managed is 49. Location:37% frontal,19% ethmoidal,19% frontoethmoidal,19% sphenoidal,6% maxillary. The iatrogenic cause was 44%. Symptoms included proptosis, external swelling, nasal block, and discharge, and vision loss. Complications were orbital abscess and skull base defect. 14 patients underwent endoscopic procedures-excision or marsupialization. One patient underwent craniotomy; one patient combined approach was performed. One patient had a recurrence. CONCLUSION: Mucocele of the paranasal sinuses is still a rare clinical scenario and it is imperative to note that any delay in diagnosis and management can lead to expansion and erosion of the bony wall of the sinuses and causing complications.

Infant Dengue a 10-Year Experience from a Tertiary Center in South India

2021 ◽  
Author(s):  
Nabaneeta Dash ◽  
Reshmi Aby ◽  
Madhan Kumar ◽  
Asha Mary Abraham ◽  
Winsley Rose
Keyword(s):  
Serum Albumin ◽  
Respiratory Symptoms ◽  
South India ◽  
Immunoglobulin M ◽  
Severe Dengue ◽  
Severe Thrombocytopenia ◽  
Lower Serum ◽  
Tertiary Center ◽  
Upper Respiratory ◽  
Upper Respiratory Symptoms

Dengue remains a major problem in the tropics. Several Asian countries have reported an increasing trend in the proportion of infants with dengue fever. However, most studies are limited to case reports or small case series from isolated outbreaks. We planned this study to look at clinico-laboratory profile, outcome, and predictors of severity in a large cohort of infants over a decade. Electronic medical records of infants admitted at a tertiary center of South India, with laboratory confirmed dengue infection between 2009 and 2019 were reviewed. Diagnosis was based on detection of NS-1 antigen and/or immunoglobulin M antibody against DENV(dengue virus) or positive DENV RNA polymerase chain reaction in infants presenting with acute febrile illness and clinical features consistent with dengue. Of 395 children with dengue admitted during study period, 99 (25%) were infants. A cyclical incidence pattern was noted, with higher cases in alternate years. Fever (99%) was most common, followed by gastrointestinal symptoms (vomiting, diarrhea—28%) and upper respiratory symptoms (cough, coryza—22%). Fifty-three infants had severe dengue, and 39 had shock. Fourteen children had multiorgan dysfunction syndrome, and 13 died. Infants with severe dengue were older than those with nonsevere disease, had lower serum albumin and greater frequency of severe thrombocytopenia, and had coagulopathy. On multivariable analysis, low serum albumin predicted development of severe dengue [P = 0.003, odds ratio 12.4 (95% confidence interval: 2.42–63.7)]. Dengue in infants may be challenging to recognize because of its undifferentiated presentation, with gastrointestinal and upper respiratory symptoms that are similar to other viral illness. Severe dengue is common in this sample, and lower serum albumin at presentation was predictive of severe disease.

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