scholarly journals PIN31 TOTAL TREATMENT COST OF LINEZOLID COMPARED TO VANCOMYCIN IN MRSA INFECTIONS

2008 ◽  
Vol 11 (3) ◽  
pp. A102
Author(s):  
B Borgman ◽  
M Ekman
2017 ◽  
pp. 100-106
Author(s):  
Thuan Huynh ◽  
Minh Tam Nguyen

Introduction: Child injury is a significant burden for community health care in Vietnam. Besides the fatal injuries, millions of children need hospital care for non-fatal injuries. Investigation on treatment cost and economic burden of the most common non-fatal injuries such as falls, burns, and traffic injuries is very necessary. Objectives: (1) Describe the patterns of falls, burns, and traffic injuries among children admitted with injuries to the Quang Nam Pediatric Hospital; (2) Analyze the treatment cost for falls, burns, and traffic injuries of these patients. Methods: A cross-sectional study on 424 pediatric patients under 16 year old admitted with falls, burns, and traffic injuries to the Quang Nam Pediatric Hospital from 01/6/2014 to 31/3/2015. Results: Most of participants admitted to the hospital for falls (66%), traffic injuries (22,4%). Mild injuries was dominated, burns and traffic injuries were more serious in almost cases and the average of PTS index was 9.4 points. Average total treatment cost was 1,259,200 VN dong, direct cost accounted for 68.4% of total treatment cost. Treatment costs of burns and traffic injuries were higher than that of falls. Key words: burden of disease, treatment cost, injury, children


2021 ◽  
Vol 61 (4) ◽  
pp. 205-10
Author(s):  
Rini Sulviatni ◽  
Khonsa Hartsu Syuhada ◽  
Hanny Krissanti ◽  
Denny Purnama

Background High bilirubin levels may lead to complications such as bilirubin encephalopathy or even death. Therefore, neonatal hyperbilirubinemia patients require appropriate treatment in the form of phototherapy or exchange transfusion. With the advancement of technology, various types of phototherapy, such as the cylindrical intensive phototherapy (bilisphere) and double LED, are now available. Objective To compare cylindrical intensive phototherapy to double surface LED phototherapy in neonatal hyperbilirubinemia. Methods This cohort study was conducted in neonates with hyperbilirubinemia at at Syamsudin SH Hospital, Sukabumi, West Java, who were treated with either cylindrical intensive phototherapy or double surface LED phototherapy. The variables observed were subjects’ characteristics, bilirubin levels pre- and post-therapy, duration of phototherapy, length of stay, and total treatment cost. The data were analyzed using univariate and bivariate analyses. Results Of 47 neonates, the mean bilirubin levels were 19.36 mg/dL pre-therapy and 12.26 mg/dL post-therapy. Subjects’ overall mean duration of phototherapy was 24 hours, mean length of stay was 1 day, and mean cost of treatment was IDR 813,175. There was no significant difference in the bilirubin decrease between the cylindrical intensive phototherapy and double LED groups. However, there were significant differences between the cylindrical intensive phototherapy and double LED groups in duration of phototherapy (10.75 vs. 75.17 hours, respectively (P<0.000), mean length of stay (1 vs. 3.13 days, respectively (P<0.000), and total cost of treatment (IDR 598,918 vs. IDR 1,036,747, respectively P<0.000). Conclusion While the decrease in bilirubin was not significantly different in neonatal hyperbilirubinemia patients who underwent cylindrical intensive phototherapy compared to double LED therapy, cylindrical intensive phototherapy relates to significant shorter phototherapy duration, length of stay, and total treatment cost. Hence, cylindrical intensive phototherapy phototherapy is considered to be more time-efficient and cost-efficient than double LED phototherapy.


Pharmacia ◽  
2019 ◽  
Vol 66 (3) ◽  
pp. 157-160
Author(s):  
Iryna Bilyk ◽  
Iryna Fedyak ◽  
Iryna Ivaniulyk Ivaniulyk ◽  
Liubomyr Havryshchuk

A comprehensive study for assessment the appointments rationality for children with meningococcal infectious (MI) in Ukraine in real clinical practice has been conducted. The doctor’s appointment sheets from 184 inpatients medical cards have been processed by the integral ABC / VEN / frequency analysis. In average, children were in the hospital (14±7) bed-days, they were granted 2908 appointments of 191 drugs by the INN. It has been established that medicine for MI etiotropic therapy took the third place in the appointments frequency. At the same time, the ABC / VEN-analysis results revealed a rational approach to pharmacotherapy.The total treatment cost was estimated at USD 25,173.59 (for one child – USD 136.81).Since currently in Ukraine inpatient children treatment is mainly provided by parents, further medical prescriptions improvement is needed in order to increase the efficiency and minimize the childrenMI therapy cost.


2021 ◽  
Author(s):  
LvWen zhang ◽  
Yan Song ◽  
Xiang Fei

Abstract This study investigated the clinical efficacy of a novel vacuum suction ureteroscopic approach in the treatment of upper ureteral calculi. A total of 160 patients with impacted upper ureteral calculi were included in this study. 50 patients underwent rigid ureteroscopic lithotripsy, 54 patients underwent flexible ureteroscopic lithotripsy, and 56 patients underwent vacuum suction ureteroscopic lithotripsy. The operative time, length of hospitalization, stone-free rate, complication rate and total treatment cost were compared among the three groups. Subgroup analysis was performed based on the stone diameter over and below 1.5 cm. Compared with the other two groups, the vacuum suction ureteroscopy group had higher stone-free rate at 3–5 days (90.0% vs. 61.9% vs. 55.6%, P < 0.05) and 1 month (96.4% vs. 77.7% vs. 74.0%, P < 0.05) postoperatively. In subgroup analysis, the stone-free rate of the vacuum suction ureteroscopy group was significantly higher when the stone diameter was > 1.5 cm at 1 month postoperatively ( P < 0.05); however, there were no differences in postoperative complications.( P > 0.05). In conclusion, the novel vacuum suction ureteroscopic lithotripsy has significantly improved the stone-free rate especially in complicated cases; however the complication and cost was not increased.


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17081-17081 ◽  
Author(s):  
P. Saramago ◽  
V. Andreozzi ◽  
J. M. Ferreira ◽  
J. Félix

17081 Background: Neutropenia (N) and febrile neutropenia (FN) are common adverse effects of chemotherapy, resulting in increased risk of infections and hospitalizations. Both conditions account for substantial health resource utilization (HRU). The objective of this study was to evaluate HRU patterns for patients (PTS) experiencing N or FN in “real world” practice and to model the corresponding HRU cost profiles. Methods: Breast and lung cancer PTS receiving granulocyte colony stimulating factor (GCSF) to treat chemotherapy- induced neutropenia (absolute neutrophil count [ANC] =1500 cell/μL) were selected from 8 Portuguese hospitals. In the absence of a comprehensive database PTS having neutropenia were originally identified from hospital pharmacies GCSF prescription lists; afterwards, HRU frequency (hospitalization, clinical visits, complementary examinations, medication, transfusions) in relation to N or FN (ANC =1000 cell/μL and body temperature= 38.5°C over one hour) was reviewed retrospectively from clinical records. Treatment costs attributed to N/FN were calculated by multiplying HRU frequency by unit costs from the Portuguese Ministry of Health costs database. To account for the skewed nature of the data costs were modelled using generalized linear models with gamma distribution and log link. Results: The study included 50 PTS with breast cancer and 48 with lung cancer. Mean (SD) age was 60.0 (12.5) years and 61.2% were women. Mean (SD) ANC at first N was 724 (433) cell/μL. FN (mean (SD) ANC 440 (370) cell/μL) was developed by 16.5% of PTS. Mean (SD) total cost of N treatment was 922 (1162) € (28% hospitalization, 5% clinical visits, 3% complementary examinations, 54% medication, 10% transfusions). Controlling for PTS clinical and sociodemographic characteristics, total treatment cost were 3.2 (95%CI:1.9–5.2) times higher for PTS with FN (p<0.001) when compared to N PTS, 4.4% (95%CI: 0.1–7.7) greater for every 100 cell/μL decrease in ANC (p=0.03) and 2.5% (95%CI: 1.0–4.1) higher per additional year of age at N or FN diagnosis (p=0.002). Conclusions: Chemotherapy-induced neutropenia direct treatment costs were substantially incremented in febrile patients. [Table: see text]


Plant Disease ◽  
1998 ◽  
Vol 82 (4) ◽  
pp. 428-433 ◽  
Author(s):  
M. A. Ellis ◽  
D. C. Ferree ◽  
R. C. Funt ◽  
L. V. Madden

An inorganic (sulfur) and a conventional organic fungicide spray program were evaluated on an apple scab-resistant (Liberty) and a scab-susceptible (McIntosh) cultivar for control of scab and for cost effectiveness. Trees of both cultivars were either nontreated, treated with inorganic fungicides only, or treated with a conventional fungicide program. McIntosh trees received full-season fungicide applications and Liberty trees received only the summer cover sprays (after petal fall) for control of summer diseases. In 1991, the number of fungicide applications ranged from 0 for nontreated Liberty to 12 for the full-schedule inorganic program on McIntosh, with both treatments providing excellent scab control. All nontreated McIntosh fruit were unmarketable due to scab infection. Due to a dry growing season and lack of summer disease development, nontreated Liberty fruit was of high quality. In 1992, the number of fungicide applications ranged from 0 for nontreated Liberty to 14 for the full-schedule inorganic treatment on McIntosh, with both treatments providing good to excellent disease control. Results were very similar in 1993. Scab incidence was low for all treatments except the nonsprayed McIntosh over all years. Over 3 years of testing, the conventional fungicide program resulted in an average of 9 and 5 applications per year for McIntosh and Liberty, respectively, compared to 12.6 and 7 applications, respectively, for the inorganic fungicide program. The large reduction in the number of sprays for both programs was due to the elimination of all pre-petal-fall applications on Liberty; post-petal-fall applications are needed to control summer diseases such as flyspeck and sooty blotch. An economic analysis for total cost of fungicide applications for each spray program and cultivar was conducted for hypothetical 4.0-, 8.1- and 16.2-ha farms. Regardless of farm size, the cost of fungicides per ha varied among treatments and cultivars. The inorganic and conventional spray program for McIntosh had similar total costs. On Liberty, the inorganic and conventional programs had 73 and 57% less total cost, respectively, than on McIntosh. Fungicides for the conventional program on Liberty were 1.45 times more costly per ha than fungicides in the inorganic program, but the inorganic program required more applications, resulting in a small difference in total treatment cost per ha.


Author(s):  
Shahariar Islam

Cholelithiasis is one of the major problems which need cholecystectomy. Laparoscopic cholecystectomy is a newer technique. But there is a need to evaluate the cost-effectiveness of per-abdominal and laparoscopic method from patients perspective. The study was performed to assess the cost-effectiveness of per-abdominal and laparoscopic cholecystectomy.
Materials and Methods:
This cross sectional study in two sample situations was conducted among 90 purposively selected cholecystectomy patients of which 60 patients underwent laparoscopic cholecystectomy (LC) and 30 patients underwent per-abdominal cholecystectomy (PAC) from three tertiary level government hospitals of Dhaka, Bangladesh at the time of their discharge through face to face interview using a semi-structured questionnaire and checklist. The study found average age 45.33(13.63) and 41.75(13.39) years in PAC and LC respectively. Average monthly income was less in the PAC group Tk.23200.00(12374.61) than LC Tk.24925.00(12166.86). Average duration of suffering from cholelithiasis was 9.50(8.68) months in PAC group and 12.43(17.49) months in LC group. Average hospital stay was 13.97(6.88) days in PAC group while it was 12.02(6.66) days in LC group. Average treatment cost was little higher Tk.21927.407795.89 in LC group than Tk.21466.306261.42 in the PAC group. Both direct cost and indirect cost were also higher in LC group (Tk.18668.305965.67 and Tk.3661.324229.85) than in PAC group (Tk.18228.004624.75 and Tk.3350.004124.58). But these differences were not statistically significant. In both groups treatment cost significantly increased with duration of hospitalization (correlation, p<0.01). Cure rate was significantly high in LC group (94.4%) than in PAC group (86.7%) (χ2, p<0.05).
This study revealed LC method is cost-effective than PAC method. Total treatment cost in LC can be reduced by minimizing hospital cost, laboratory cost and securing the income of the patients which enhance the economic load.


2020 ◽  
Vol 38 (10) ◽  
pp. 1087-1092
Author(s):  
Ronei de Almeida ◽  
Daniele Maia Bila ◽  
Bianca Ramalho Quintaes ◽  
Juacyara Carbonelli Campos

The reverse osmosis (RO) process has been increasingly applied to landfill leachate treatment. The published literature reports several studies that investigated the technical feasibility of RO. However, information about process costs is scarce. Also, companies that run leachate treatment plants do not provide actual costs. To fill this gap, this study aimed to evaluate the treatment costs of a full-scale RO for the treatment of landfill leachate located in Rio de Janeiro State, Brazil. A procedure was proposed to estimate the capital expenses (CAPEX), operational expenses (OPEX), and specific total treatment cost, the total cost per m3 of treated leachate, of the leachate treatment by membrane process, and the results obtained are discussed. The CAPEX for this full-scale RO was estimated at MUS$ 1.413, and OPEX ranged from US$ 0.132 to US$ 0.265 m−3 per year. The cost of leachate treatment has been estimated at US$ 8.58 m−3 considering the operation of the RO-unit for 20 years after landfill closure.


Water ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1849 ◽  
Author(s):  
Javier Tejera ◽  
Ruben Miranda ◽  
Daphne Hermosilla ◽  
Iñigo Urra ◽  
Carlos Negro ◽  
...  

This study focuses on the treatment of a mature landfill leachate by coagulation and photo-Fenton at different conditions. Optimal coagulation is carried out with ferric chloride in acid conditions; and with alum in near-neutral conditions, to minimize the use of sulphuric acid for pH adjustment (1 g/L vs. 7.2 g/L), the generation of sludge and the increase of conductivity in the final effluent. In both cases, a similar chemical oxygen demand (COD) removal is obtained, higher than 65%, which is high enough for a subsequent photo-Fenton treatment. However, the removal of absorbance at 254 nm (UV-254) was significantly higher with ferric chloride (83% vs. 55%), due to the important removal of humic acids at acid pH. The best results for coagulation are 2 g/L ferric chloride at initial pH = 5 and 5 g/L alum at initial pH = 7. After coagulation with ferric chloride, the final pH (2.8) is adequate for a homogeneous photo-Fenton using the remaining dissolved iron (250 mg/L). At these conditions, using a ratio H2O2/COD = 2.125 and 30 min contact time, the biodegradability increased from 0.03 to 0.51. On the other hand, the neutral pH after alum coagulation (6.7) allows the use of zero valent iron (ZVI) heterogeneous photo-Fenton. In this case, a final biodegradability of 0.32 was obtained, after 150 min, using the same H2O2/COD ratio. Both treatments achieved similar results, with a final COD, UV-254 and color removal greater than 90%. However, the economic assessment shows that the approach of ferric chloride + homogeneous photo-Fenton is much cheaper (6.4 €/m3 vs. 28.4 €/m3). Although the discharge limits are not achieved with the proposed combination of treatments, the significant increase of the pre-treated leachate biodegradability allows achieving the discharge limits after a conventional biological treatment such as sequencing batch reactor, which would slightly increase the total treatment cost.


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