scholarly journals 553: Predicting event rate and failure to recover baseline lung function after acute respiratory events in school-age children with cystic fibrosis

2021 ◽  
Vol 20 ◽  
pp. S261
Author(s):  
L. Perrem ◽  
S. Stanojevic ◽  
S. Davis ◽  
M. Solomon ◽  
N. Sweezey ◽  
...  
Thorax ◽  
2021 ◽  
pp. thoraxjnl-2020-215515
Author(s):  
Hélène Amazouz ◽  
Nicolas Bougas ◽  
Michel Thibaudon ◽  
Guillaume Lezmi ◽  
Nicole Beydon ◽  
...  

BackgroundDaily levels of ambient air pollution and pollen may affect lung function but have rarely been studied together. We investigated short-term exposure to pollen and air pollution in relation to lung function in school-age children from a French population-based birth cohort.MethodsThis study included 1063 children from the PARIS (Pollution and Asthma Risk: an Infant Study) cohort whose lung function and FeNO measurements were performed at age 8 years old. Exposure data were collected up to 4 days before testing. We estimated daily total pollen concentration, daily allergenic risk indices for nine pollen taxa, as well as daily concentrations of three air pollutants (particulate matter less than 10 µm (PM10), nitrogen dioxide (NO2), ozone (O3)). Children with similar pollen and air pollution exposure were grouped using multidimensional longitudinal cluster analysis. Associations between clusters of pollen and air pollution exposure and respiratory indices (FEV1, FVC, FeNO) were studied using multivariable linear and logistic regression models adjusted for potential confounders.ResultsFour clusters of exposure were identified: no pollen and low air pollution (Cluster 1), grass pollen (Cluster 2), PM10 (Cluster 3) and birch/plane-tree pollen with high total pollen count (Cluster 4). Compared with children in Cluster 1, children in Cluster 2 had significantly lower FEV1 and FVC levels, and children from Cluster 3 had higher FeNO levels. For FEV1 and FVC, the associations appeared stronger in children with current asthma. Additional analysis suggested a joint effect of grass pollen and air pollution on lung function.ConclusionDaily ambient chemical and biological air quality could adversely influence lung function in children.


2010 ◽  
Vol 181 (9) ◽  
pp. 969-974 ◽  
Author(s):  
Sarah J. Kotecha ◽  
W. John Watkins ◽  
Jonathan Heron ◽  
John Henderson ◽  
Frank D. Dunstan ◽  
...  

Author(s):  
Shannon Simpson ◽  
Karla Logie ◽  
Maureen Verheggen ◽  
Christopher O'Dea ◽  
Andrew Wilson ◽  
...  

1991 ◽  
Vol 144 (3_pt_1) ◽  
pp. 655-662 ◽  
Author(s):  
Gerald L. Strope ◽  
Paul W. Stewart ◽  
Frederick W. Henderson ◽  
Sally S. Ivins ◽  
Helen C. Stedman ◽  
...  

Author(s):  
Liene Martinsone-Bērzkalne ◽  
Silvija Umbraško ◽  
Ilva Duļevska ◽  
Liāna Pļaviņa ◽  
Viktorija Cīrule ◽  
...  

AbstractThe number of people with excess weight increases every year. Overweight and obesity in childhood can cause several chronic diseases in adulthood. Children with excess body mass develop more morphological and functional changes, including pulmonary functions. One of the common methods to assess lung function is spirometry. This method is a challenge in assessing lung function for pre-school age children. The aim of this study was to evaluate the correlation between lung vital capacity and body mass index for the pre-school children aged 3–7 years in Rīga. In total 995 pre-school children were included in the study. An informative consent and questionnaire about the development of each individual child was filled in by parents. Several measurements were performed, including height, body mass, and lung vital capacity. This is the first study in Latvia where several morphologic and somatometric measurements were determined in children of pre-school age. There was a positive and statistically significant correlation between lung vital capacity and body height, mass, and chest circumference. The correlation between lung vital capacity and body mass index was not statistically significant. The main results do not differ from the results of similar studies in other countries. The obtained results will help to create a standard of morphological and somatometric parameters in pre-school aged children in Rīga region.


PEDIATRICS ◽  
1997 ◽  
Vol 99 (5) ◽  
pp. 665-671
Author(s):  
Lori J. Stark ◽  
Mary M. Mulvihill ◽  
Elissa Jelalian ◽  
Anne M. Bowen ◽  
Scott W. Powers ◽  
...  

Study Objective. To investigate calorie intake, behavioral eating styles, and parent perception of eating behavior of school-age children with cystic fibrosis (CF) compared with healthy peers. Design. A two-group comparison study. Setting. A clinical sample of 28 school-age children with CF and a community sample of 28 healthy peers matched for age (6 to 12 years) and socioeconomic status. Measurements and Main Results. The children with CF consumed more calories per day (2175 cal/d) than the control children (1875 cal/d) and achieved a significantly higher recommended daily allowance (RDA) of energy (128% of the RDA) than the control children (91.61% of the RDA). Fifty-four percent of the CF sample were achieving the CF dietary recommendations of 120% of the RDA. Despite this energy intake, the CF sample was significantly below the control sample on weight (24.56 vs 31.23 kg), height (125.48 vs 133.06 cm), andz score for weight (−0.811 vs 0.528) and height (−0.797 vs 0.371). On measures of behavioral eating style, the CF sample had significantly longer meals (23.90 min) than the control sample (17.34 min) and had a significantly slower pace of eating (43.27% 10-second intervals with bites) than the control sample (51.29% 10-second intervals with bites) but did not differ significantly on the number of calories consumed during dinner. On a measure of parent report of mealtime behaviors, parents of the children with CF rated mealtime behavior problems of “dawdles” and “refuses food” as more intense (mean, 3.46) than did the parents of control children (mean, 2.67). For the CF sample, a significant correlation was found between the parent intensity ratings of problem behavior in general and meal duration (r = .48), and a significant negative correlation was found between the parent intensity ratings of problem mealtime behaviors and the percentage of intervals with bites (pace of meal) (r = −.533). Conclusions. Although the school-age children with CF were consuming more calories per day than their healthy peers, and more than 50% of the children in the CF sample were at or above the CF dietary recommendations, the children in the CF sample were significantly below the control children on measures of weight and height. The behavioral data suggest that increased caloric intake is not without cost, because the CF sample spent an additional 7 minutes per day at dinner and ate their meals at a slower pace than their healthy peers. These data were associated with higher intensity ratings of mealtime behaviors by parents of children with CF. These findings point to the need for individualized assessment of energy needs for school-age children with CF and comprehensive programs that teach parents behavioral strategies to motivate their children to meet these higher energy requirements in an adaptive manner.


Author(s):  
Ephraim Bar-Yishay ◽  
Elena Matyashchuk ◽  
Dario Prais ◽  
Hannah Blau ◽  
Eytan Kaplan

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