0100: Association between social class and metabolic syndrome in a Tunisian population

Abstract Objective To describe the prevalence of Spanish workers with Metabolic Syndrome (MetS) and those at risk of developing MetS in 2015. Methods Cross-sectional study of workers (n = 15 614). We used a modified definition of the NCEP:ATPIII criteria for MetS (we used body mass index (BMI) above 28.8 kg/m2 instead of the waist circumference criterion). We calculated the prevalence of MetS (having at least three components) and of being at risk of MetS (having one or two components). We calculated adjusted odds ratios (aOR) of MetS according to socio-economic and workplace characteristics. Results The proportions of workers with and at risk of MetS were 7.1 and 31.9%, respectively. The most prevalent criterion was having a BMI > 28.8 kg/m2 (24.1%) in men and cHDL < 40 mg/dl in women (12.9%). There were significant associations between MetS and men (aOR compared to women = 3.73, CI 95%: 3.19; 4.36); age (higher among oldest, aOR = 5.75, CI 95%: 4.37;7.56); and social class (higher among lower social class, aOR = 2.03, CI 95%: 1.65;2.48). Conclusion Reducing any of the five MetS components, while taking into account the differences found by socio-economic and workplace characteristics, should be one priority for reducing MetS prevalence.

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Social class and metabolic syndrome in populations from Tunisia and Spain

Diabetology & Metabolic Syndrome ◽

10.1186/s13098-015-0084-6 ◽

2015 ◽

Vol 7 (1) ◽

Cited By ~ 12

Author(s):

Fadoua Gannar ◽

Antonio Cabrera de León ◽

Buenaventura Brito Díaz ◽

María Del Cristo Rodríguez Pérez ◽

Itahisa Marcelino Rodríguez ◽

...

Keyword(s):

Metabolic Syndrome ◽

Social Class

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Relationship of C-reactive protein with components of the metabolic syndrome in a Tunisian population

European Journal of Internal Medicine ◽

10.1016/j.ejim.2011.10.011 ◽

2012 ◽

Vol 23 (1) ◽

pp. e5-e9 ◽

Cited By ~ 10

Author(s):

Hanen Belfki ◽

Samir Ben Ali ◽

Souha Bougatef ◽

Decy Ben Ahmed ◽

Najet Haddad ◽

...

Keyword(s):

Metabolic Syndrome ◽

Tunisian Population ◽

C Reactive Protein ◽

Reactive Protein ◽

The Metabolic Syndrome ◽

Relationship Of

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Combined Effects of the C161T and Pro12Ala PPARγ2 Gene Variants with Insulin Resistance on Metabolic Syndrome: A Case–Control Study of a Central Tunisian Population

Journal of Molecular Neuroscience ◽

10.1007/s12031-013-0161-y ◽

2013 ◽

Vol 52 (4) ◽

pp. 487-492 ◽

Cited By ~ 4

Author(s):

Sarraj Mohamed Youssef ◽

Najah Mohamed ◽

Slimani Afef ◽

Ben Hamda Khaldoun ◽

Neffati Fadoua ◽

...

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Case Control Study ◽

Case Control ◽

Tunisian Population ◽

Gene Variants ◽

Combined Effects ◽

Control Study

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Metabolic syndrome determinants in an urban population from Brazil: Social class and gender-specific interaction

International Journal of Cardiology ◽

10.1016/j.ijcard.2007.07.097 ◽

2008 ◽

Vol 129 (2) ◽

pp. 259-265 ◽

Cited By ~ 49

Author(s):

Guilherme Figueiredo Marquezine ◽

Camila Maciel Oliveira ◽

Alexandre C. Pereira ◽

José E. Krieger ◽

José G. Mill

Keyword(s):

Metabolic Syndrome ◽

Social Class ◽

Urban Population ◽

Specific Interaction ◽

And Gender ◽

Gender Specific

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Adiponectin and Metabolic Syndrome in a Tunisian Population

Inflammation ◽

10.1007/s10753-011-9383-8 ◽

2011 ◽

Vol 35 (3) ◽

pp. 828-833

Author(s):

Samir Ben Ali ◽

Riadh Jemaa ◽

Bouchra Ftouhi ◽

Amani Kallel ◽

Moncef Feki ◽

...

Keyword(s):

Metabolic Syndrome ◽

Tunisian Population

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Association of rs662799 variant and APOA5 gene haplotypes with metabolic syndrome and its components: a meta-analysis in North Africa

Bioscience Reports ◽

10.1042/bsr20200706 ◽

2020 ◽

Vol 40 (8) ◽

Author(s):

Meriem Hechmi ◽

Hamza Dallali ◽

Meriem Gharbi ◽

Haifa Jmel ◽

Meriem Fassatoui ◽

...

Keyword(s):

Metabolic Syndrome ◽

North Africa ◽

Meta Analysis ◽

Geographic Origin ◽

Northern Region ◽

Additive Models ◽

Tunisian Population ◽

Genotype Distribution ◽

Apolipoprotein A5 ◽

Apoa5 Gene

Abstract Apolipoprotein A5 (APOA5) has been linked to metabolic syndrome (MetS) in several populations. In North Africa, only the Tunisian and Moroccan populations were investigated. Our aim is to assess the association between APOA5 gene variant (rs662799) and haplotypes with MetS in Tunisian population and to perform a meta-analysis in North Africa. A total of 594 Tunisian participants were genotyped for polymorphism rs662799 using KASPar technology. Two polymorphisms rs3135506 and rs651821 in APOA5 gene genotyped in our previous study, were used in addition to rs662799 to assess the haplotype association with MetS. The genotype of 875 participants was used for the meta-analysis. Statistical analyses were performed with R software. The rs662799 increases the risk of MetS under the dominant (P=0.018) and the additive models (P=0.028) in the Tunisian population. After stratification of the cohort following the sex and the geographic origin, a positive association of rs662799 with MetS was found for participant from the Northern region and for the women group. Only the haplotype AGT showed a significant association with MetS by decreasing the risk of the disease. The meta-analysis reported a significant association of rs662799 and rs3135506 with MetS. Our results showed a significant association between the APOA5 gene variants rs662799 and haplotypes with MetS and its traits in Tunisia. An impact of the sex and the geographic origin on the genotype distribution was highlighted. Our funding emphasizes the role of APOA5 in the development of MetS in North Africa.

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