scholarly journals Consumption of a fermented dairy product containing the probioticLactobacillus caseiDN-114 001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial

2009 ◽  
Vol 103 (1) ◽  
pp. 58-68 ◽  
Author(s):  
E. Guillemard ◽  
F. Tondu ◽  
F. Lacoin ◽  
J. Schrezenmeir
Keyword(s):  
Controlled Trial ◽  
Dairy Product ◽  
Probiotic Strain ◽  
Control Group ◽  
Cumulative Number ◽  
Upper Respiratory Tract ◽  
Fermented Dairy Product ◽  
Fermented Product ◽  
Tract Infections ◽  
Fermented Dairy

Common infectious diseases (CID) of the airways and the gastrointestinal tract are still a considerable cause of morbidity and mortality in elderly. The present study examined the beneficial effect of a dairy product containing the probiotic strainLactobacillus caseiDN-114 001 (fermented product) on the resistance of free-living elderly to CID. The study was multicentric, double blind and controlled, involving 1072 volunteers (median age = 76·0 years) randomised for consumption of either 200 g/d of fermented (n537) or control (non-fermented) dairy product (n535) for 3 months, followed by an additional 1 month's follow-up. The results showed that, when considering all CID, the fermented product significantly reduced the average duration per episode of CID (6·5v. 8 d in control group;P = 0·008) and the cumulative duration of CID (7v. 8 d in control group;P = 0·009). Reduction in both episode and cumulative durations was also significant for all upper respiratory tract infections (URTI;P < 0·001) and for rhinopharyngitis (P < 0·001). This was accompanied with an increase ofL. caseispecies in stools throughout the fermented product consumption (2–3·8 × 107equivalents of colony-forming unit/g of stools,P < 0·001). The cumulative number of CID (primary outcome) was not different between groups nor was the CID severity, fever, pathogens' occurrence, medication, immune blood parameters and quality of life. The fermented product was safe and well tolerated. In conclusion, consumption of a fermented dairy product containing the probiotic strainL. caseiDN-114 001 in elderly was associated with a decreased duration of CID in comparison with the control group, especially for URTI such as rhinopharyngitis.

scholarly journals The influence of a dietary advice on recurrent upper respiratory tract infections in children: a randomized controlled trial.

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Ellen van der Gaag ◽  
Ruben Brandsema ◽  
Job van der Palen ◽  
Thalia Hummel
Keyword(s):  
Supportive Care ◽  
Respiratory Tract Infections ◽  
Controlled Trial ◽  
Intervention Group ◽  
Dietary Advice ◽  
Control Group ◽  
Upper Respiratory Tract ◽  
Randomized Controlled ◽  
Upper Respiratory ◽  
Tract Infections

AbstractIntroductionSince there is no treatment for children suffering from upper respiratory tract infections (URTI) without immunological disorders, we searched for a possible tool to improve the health of these children.We evaluated whether a dietary advice including standard supportive care, can decrease the number and duration of URTI compared to standard supportive care in children aged 1–4 years with recurrent URTI.Material and MethodsDesign: A multicenter randomized controlled trial, with an intervention group receiving the dietary advice plus standard supportive care and a control group receiving standard supportive care alone.Setting: 3 Outpatient clinics in The Netherlands (urban and rural).Patients: 118 Children aged 1–4 years with recurrent URTIs.Intervention: A dietary advice consisting of five times per week green vegetables, 3 times per week beef, 300 mL whole milk per day, whole dairy butter on bread every day. Portion sizes are age appropriate. The intervention lasted for 6 months.ResultsChildren in the intervention group had 4.8 (1.6–9.5) days per month with symptoms of an URTI in the last three months of the study, compared to 7.7 (4.0–12.3) in the control group (p = 0.03). The total number of URTIs during the study period of 6 months was 5,7 (± 0,55) versus 6.8 (± 0,49) respectively (p = 0.068). Total use of antibiotics was markedly reduced in the intervention group (p = 0.034), as well as the visits to the general practitioner (p = 0.031), therefore possibly reducing healthcare costs.No adverse effects were observed in the lipid profiles, nor in growth parameters (weight, height, BMI).Discussion and conclusionsThis study shows a reduced number of days with symptoms of an URTI following a dietary advice consisting of green vegetables, beef and whole diary products. It did not significantly lower the number of infections. No adverse effects were observed.RegistrationThis trial is registered in the Dutch Trial Register, NTR4898, www.trialregister.nl.

scholarly journals Influence of Dietary Advice Including Green Vegetables, Beef, and Whole Dairy Products on Recurrent Upper Respiratory Tract Infections in Children: A Randomized Controlled Trial

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 272 ◽  
Author(s):  
Ellen van der Gaag ◽  
Ruben Brandsema ◽  
Rosan Nobbenhuis ◽  
Job van der Palen ◽  
Thalia Hummel
Keyword(s):  
Supportive Care ◽  
Respiratory Tract Infections ◽  
Controlled Trial ◽  
Dietary Advice ◽  
Control Group ◽  
Upper Respiratory Tract ◽  
Randomized Controlled ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Advice Group

Background: Since no treatment exists for children suffering from upper respiratory tract infections (URTIs) without immunological disorders, we searched for a possible tool to improve the health of these children. Aim: We evaluated whether dietary advice (based on food matrix and food synergy), including standard supportive care, can decrease the number and duration of URTIs in children with recurrent URTIs. Design and Setting: This study was a multicenter randomized controlled trial in two pediatric outpatient clinics in the Netherlands, with 118 children aged one to four years with recurrent URTIs. The dietary advice group received dietary advice plus standard supportive care, while the control group received standard supportive care alone for six months. The dietary advice consisted of green vegetables five times per week, beef three times per week, 300 mL whole milk per day, and whole dairy butter on bread every day. Portion sizes were age-appropriate. Results and Conclusion: Children in the dietary advice group had 4.8 (1.6–9.5) days per month with symptoms of an URTI in the last three months of the study, compared to 7.7 (4.0–12.3) in the control group (p = 0.028). The total number of URTIs during the six-month study period was 5.7 (±0.55) versus 6.8 (±0.49), respectively (p = 0.068). The use of antibiotics was significantly reduced in the dietary advice group, as well as visits to a general practitioner, thereby possibly reducing healthcare costs. The results show a reduced number of days with symptoms of a URTI following dietary advice. The number of infections was not significantly reduced.

scholarly journals A probiotic fermented dairy product improves immune response to influenza vaccination in the elderly

2008 ◽  
Vol 67 (OCE5) ◽  
Author(s):  
J. Aubin ◽  
M. Remigy ◽  
L. Verseil ◽  
R. Bourdet-Sicard ◽  
S. Vaudaine ◽  
...  
Keyword(s):  
Immune Response ◽  
Influenza Vaccination ◽  
Dairy Product ◽  
The Elderly ◽  
Fermented Dairy Product ◽  
Fermented Dairy
Sign in / Sign up

Export Citation Format

Share Document